Patents by Inventor James P. Light

James P. Light has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9211112
    Abstract: Provided herein is technology relating to collecting and preparing samples. For example, the technology relates particularly, but not exclusively, to devices, systems, and kits that allow a subject to collect and prepare a sample for analysis.
    Type: Grant
    Filed: August 16, 2012
    Date of Patent: December 15, 2015
    Assignee: EXACT SCIENCES CORPORATION
    Inventors: Graham P. Lidgard, Michael J. Domanico, Keith Fourrier, James P. Light, II, Scott Castanon, Keith Kopitzke
  • Patent number: 9169511
    Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.
    Type: Grant
    Filed: December 31, 2013
    Date of Patent: October 27, 2015
    Assignee: EXACT SCIENCES CORPORATION
    Inventors: Janelle J. Bruinsma, Michael J. Domanico, Graham P. Lidgard, Hongzhi Zou, William G. Weisburg, Hemanth D. Shenoi, James P. Light, II, Keith Kopitzke, John Zeis
  • Patent number: 9163278
    Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.
    Type: Grant
    Filed: December 31, 2013
    Date of Patent: October 20, 2015
    Assignee: EXACT SCIENCES CORPORATION
    Inventors: Janelle J. Bruinsma, Michael J. Domanico, Graham P. Lidgard, Hongzhi Zou, William G. Weisburg, Hemanth D. Shenoi, James P. Light, II, Keith Kopitzke, John Zeis
  • Publication number: 20150284770
    Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.
    Type: Application
    Filed: May 15, 2015
    Publication date: October 8, 2015
    Inventors: Janelle J. Bruinsma, Michael J. Domanico, Graham P. Lidgard, Hongzhi Zou, William G. Weisburg, Hemanth D. Shenoi, James P. Light, II, Keith Kopitzke, John Zeis
  • Publication number: 20150176063
    Abstract: Provided herein is technology relating to processing and preparing samples and particularly, but not exclusively, to methods, systems, and kits for removing assay inhibitors, e.g., compounds that inhibit polymerase chain reaction, from samples comprising nucleic acids. In particular, the technology is directed toward treating crude sample preparations, such as supernatants from homogenized stool samples, with insoluble polyvinylpyrrolidone (PVP) to form PVP-assay inhibitor complexes, and filtration to separate the PVP-assay inhibitor complexes from the crude sample preparations to produce clarified samples that exhibit reduced assay inhibition.
    Type: Application
    Filed: March 3, 2015
    Publication date: June 25, 2015
    Inventors: Janelle J. Bruinsma, Hemanth D. Shenoi, Michael J. Domanico, James P. Light, II
  • Patent number: 9057098
    Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.
    Type: Grant
    Filed: December 31, 2013
    Date of Patent: June 16, 2015
    Assignee: Exact Sciences Corporation
    Inventors: Janelle J. Bruinsma, Hemanth D. Shenoi, Michael J. Domanico, James P. Light, II, Keith Kopitzke, John Zeis
  • Patent number: 9000146
    Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting multiple DNA targets from a human stool sample with, for example, methods employing spin filtration techniques.
    Type: Grant
    Filed: May 11, 2012
    Date of Patent: April 7, 2015
    Assignee: Exact Sciences Corporation
    Inventors: Janelle J. Bruinsma, Michael J. Domanico, Graham P. Lidgard, Hongzhi Zou, William G. Weisburg, Hemanth D. Shenoi, James P. Light, II
  • Patent number: 8999176
    Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.
    Type: Grant
    Filed: December 31, 2013
    Date of Patent: April 7, 2015
    Assignee: Exact Sciences Corporation
    Inventors: Michael J. Domanico, James P. Light, II, Keith Kopitzke, John Zeis
  • Patent number: 8993341
    Abstract: Provided herein is technology relating to processing and preparing samples and particularly, but not exclusively, to methods, systems, and kits for removing assay inhibitors, e.g, compounds that inhibit polymerase chain reaction, from samples comprising nucleic acids. In particular, the technology is directed toward treating crude sample preparations, such as supernatants from homogenized stool samples, with insoluble polyvinylpyrrolidone (PVP) to form PVP-assay inhibitor complexes, and spin filtration to separate the PVP-assay inhibitor complexes from the crude sample preparations to produce clarified samples that exhibit reduced assay inhibition.
    Type: Grant
    Filed: May 11, 2012
    Date of Patent: March 31, 2015
    Assignee: Exact Sciences Corporation
    Inventors: Janelle J. Bruinsma, Hemanth D. Shenoi, Michael J. Domanico, James P. Light, II
  • Patent number: 8980107
    Abstract: Provided herein is technology relating to filtration and particularly, but not exclusively, to filters and methods for filtering by means of centrifugation.
    Type: Grant
    Filed: May 11, 2012
    Date of Patent: March 17, 2015
    Assignee: Exact Sciences Corporation
    Inventors: Micheal J. Domanico, James P. Light, II, Keith Koptizke, John Zeis
  • Publication number: 20140194609
    Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.
    Type: Application
    Filed: December 31, 2013
    Publication date: July 10, 2014
    Applicant: EXACT SCIENCES CORPORATION
    Inventors: Michael J. Domanico, James P. Light, II, Keith Kopitzke, John Zeis
  • Publication number: 20140194608
    Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.
    Type: Application
    Filed: December 31, 2013
    Publication date: July 10, 2014
    Applicant: EXACT SCIENCES CORPORATION
    Inventors: Janelle J. Bruinsma, Michael J. Domanico, Graham P. Lidgard, Hongzhi Zou, William G. Weisburg, Hemanth D. Shenoi, James P. Light, II, Keith Kopitzke, John Zeis
  • Publication number: 20140193813
    Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.
    Type: Application
    Filed: December 31, 2013
    Publication date: July 10, 2014
    Applicant: EXACT SCIENCES CORPORATION
    Inventors: Janelle J. Bruinsma, Hemanth D. Shenoi, Michael J. Domanico, James P. Light, II, Keith Kopitzke, John Zeis
  • Publication number: 20140194607
    Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.
    Type: Application
    Filed: December 31, 2013
    Publication date: July 10, 2014
    Applicant: EXACT SCIENCES CORPORATION
    Inventors: Janelle J. Bruinsma, Michael J. Domanico, Graham P. Lidgard, Hongzhi Zou, William G. Weisburg, Hemanth D. Shenoi, James P. Light, II, Keith Kopitzke, John Zeis
  • Patent number: 8615368
    Abstract: An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations in which discrete aspects of the assay are performed on fluid samples contained in sample vessels. The analyzer includes stations for automatically preparing a sample, incubating the sample, preforming an analyte isolation procedure, ascertaining the presence of a target analyte, and analyzing the amount of a target analyte. An automated receptacle transporting system moves the sample vessels from one station to the next. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte, and, in one embodiment, a method for real-time monitoring of the amplification process.
    Type: Grant
    Filed: March 10, 2006
    Date of Patent: December 24, 2013
    Assignee: Gen-Probe Incorporated
    Inventors: James P. Light, II, James M. Carrick
  • Publication number: 20130211286
    Abstract: Provided herein is technology relating to collecting and preparing samples. For example, the technology relates particularly, but not exclusively, to devices, systems, and kits that allow a subject to collect and prepare a sample for analysis.
    Type: Application
    Filed: August 16, 2012
    Publication date: August 15, 2013
    Applicant: EXACT SCIENCES CORPORATION
    Inventors: Graham P. Lidgard, Michael J. Domanico, Keith Fourrier, James P. Light, II, Scott Castanon, Keith Kopitzke
  • Publication number: 20120285900
    Abstract: Provided herein is technology relating to filtration and particularly, but not exclusively, to filters and methods for filtering by means of centrifugation.
    Type: Application
    Filed: May 11, 2012
    Publication date: November 15, 2012
    Applicant: EXACT SCIENCES CORPORATION
    Inventors: Michael J. Domanico, James P. Light, II, Keith Koptizke, John Zeis
  • Publication number: 20120288957
    Abstract: Provided herein is technology relating to processing and preparing samples and particularly, but not exclusively, to methods, systems, and kits for removing assay inhibitors from samples comprising nucleic acids.
    Type: Application
    Filed: May 11, 2012
    Publication date: November 15, 2012
    Applicant: Exact Sciences Corporation
    Inventors: Janelle J. Bruinsma, Hemanth D. Shenoi, Michael J. Domanico, James P. Light, II
  • Publication number: 20120288868
    Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.
    Type: Application
    Filed: May 11, 2012
    Publication date: November 15, 2012
    Applicant: EXACT SCIENCES CORPORATION
    Inventors: Janelle J. Bruinsma, Michael J. Domanico, Graham P. Lidgard, Hongzhi Zou, William G. Weisburg, Hemanth D. Shenoi, James P. Light, II
  • Publication number: 20120262260
    Abstract: Provided herein is technology relating to processing samples. In particular, the technology provides articles of manufacture, apparatuses, and methods related to purifying an analyte from a sample matrix using magnetic particles.
    Type: Application
    Filed: April 18, 2011
    Publication date: October 18, 2012
    Applicant: EXACT SCIENCES CORPORATION
    Inventors: James P. Light, II, Daniel C. Miller