Patents by Inventor James P. Light
James P. Light has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 9211112Abstract: Provided herein is technology relating to collecting and preparing samples. For example, the technology relates particularly, but not exclusively, to devices, systems, and kits that allow a subject to collect and prepare a sample for analysis.Type: GrantFiled: August 16, 2012Date of Patent: December 15, 2015Assignee: EXACT SCIENCES CORPORATIONInventors: Graham P. Lidgard, Michael J. Domanico, Keith Fourrier, James P. Light, II, Scott Castanon, Keith Kopitzke
-
Patent number: 9169511Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.Type: GrantFiled: December 31, 2013Date of Patent: October 27, 2015Assignee: EXACT SCIENCES CORPORATIONInventors: Janelle J. Bruinsma, Michael J. Domanico, Graham P. Lidgard, Hongzhi Zou, William G. Weisburg, Hemanth D. Shenoi, James P. Light, II, Keith Kopitzke, John Zeis
-
Patent number: 9163278Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.Type: GrantFiled: December 31, 2013Date of Patent: October 20, 2015Assignee: EXACT SCIENCES CORPORATIONInventors: Janelle J. Bruinsma, Michael J. Domanico, Graham P. Lidgard, Hongzhi Zou, William G. Weisburg, Hemanth D. Shenoi, James P. Light, II, Keith Kopitzke, John Zeis
-
Publication number: 20150284770Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.Type: ApplicationFiled: May 15, 2015Publication date: October 8, 2015Inventors: Janelle J. Bruinsma, Michael J. Domanico, Graham P. Lidgard, Hongzhi Zou, William G. Weisburg, Hemanth D. Shenoi, James P. Light, II, Keith Kopitzke, John Zeis
-
Publication number: 20150176063Abstract: Provided herein is technology relating to processing and preparing samples and particularly, but not exclusively, to methods, systems, and kits for removing assay inhibitors, e.g., compounds that inhibit polymerase chain reaction, from samples comprising nucleic acids. In particular, the technology is directed toward treating crude sample preparations, such as supernatants from homogenized stool samples, with insoluble polyvinylpyrrolidone (PVP) to form PVP-assay inhibitor complexes, and filtration to separate the PVP-assay inhibitor complexes from the crude sample preparations to produce clarified samples that exhibit reduced assay inhibition.Type: ApplicationFiled: March 3, 2015Publication date: June 25, 2015Inventors: Janelle J. Bruinsma, Hemanth D. Shenoi, Michael J. Domanico, James P. Light, II
-
Patent number: 9057098Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.Type: GrantFiled: December 31, 2013Date of Patent: June 16, 2015Assignee: Exact Sciences CorporationInventors: Janelle J. Bruinsma, Hemanth D. Shenoi, Michael J. Domanico, James P. Light, II, Keith Kopitzke, John Zeis
-
Patent number: 9000146Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting multiple DNA targets from a human stool sample with, for example, methods employing spin filtration techniques.Type: GrantFiled: May 11, 2012Date of Patent: April 7, 2015Assignee: Exact Sciences CorporationInventors: Janelle J. Bruinsma, Michael J. Domanico, Graham P. Lidgard, Hongzhi Zou, William G. Weisburg, Hemanth D. Shenoi, James P. Light, II
-
Patent number: 8999176Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.Type: GrantFiled: December 31, 2013Date of Patent: April 7, 2015Assignee: Exact Sciences CorporationInventors: Michael J. Domanico, James P. Light, II, Keith Kopitzke, John Zeis
-
Patent number: 8993341Abstract: Provided herein is technology relating to processing and preparing samples and particularly, but not exclusively, to methods, systems, and kits for removing assay inhibitors, e.g, compounds that inhibit polymerase chain reaction, from samples comprising nucleic acids. In particular, the technology is directed toward treating crude sample preparations, such as supernatants from homogenized stool samples, with insoluble polyvinylpyrrolidone (PVP) to form PVP-assay inhibitor complexes, and spin filtration to separate the PVP-assay inhibitor complexes from the crude sample preparations to produce clarified samples that exhibit reduced assay inhibition.Type: GrantFiled: May 11, 2012Date of Patent: March 31, 2015Assignee: Exact Sciences CorporationInventors: Janelle J. Bruinsma, Hemanth D. Shenoi, Michael J. Domanico, James P. Light, II
-
Patent number: 8980107Abstract: Provided herein is technology relating to filtration and particularly, but not exclusively, to filters and methods for filtering by means of centrifugation.Type: GrantFiled: May 11, 2012Date of Patent: March 17, 2015Assignee: Exact Sciences CorporationInventors: Micheal J. Domanico, James P. Light, II, Keith Koptizke, John Zeis
-
Publication number: 20140194609Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.Type: ApplicationFiled: December 31, 2013Publication date: July 10, 2014Applicant: EXACT SCIENCES CORPORATIONInventors: Michael J. Domanico, James P. Light, II, Keith Kopitzke, John Zeis
-
Publication number: 20140194608Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.Type: ApplicationFiled: December 31, 2013Publication date: July 10, 2014Applicant: EXACT SCIENCES CORPORATIONInventors: Janelle J. Bruinsma, Michael J. Domanico, Graham P. Lidgard, Hongzhi Zou, William G. Weisburg, Hemanth D. Shenoi, James P. Light, II, Keith Kopitzke, John Zeis
-
Publication number: 20140193813Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.Type: ApplicationFiled: December 31, 2013Publication date: July 10, 2014Applicant: EXACT SCIENCES CORPORATIONInventors: Janelle J. Bruinsma, Hemanth D. Shenoi, Michael J. Domanico, James P. Light, II, Keith Kopitzke, John Zeis
-
Publication number: 20140194607Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.Type: ApplicationFiled: December 31, 2013Publication date: July 10, 2014Applicant: EXACT SCIENCES CORPORATIONInventors: Janelle J. Bruinsma, Michael J. Domanico, Graham P. Lidgard, Hongzhi Zou, William G. Weisburg, Hemanth D. Shenoi, James P. Light, II, Keith Kopitzke, John Zeis
-
Patent number: 8615368Abstract: An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations in which discrete aspects of the assay are performed on fluid samples contained in sample vessels. The analyzer includes stations for automatically preparing a sample, incubating the sample, preforming an analyte isolation procedure, ascertaining the presence of a target analyte, and analyzing the amount of a target analyte. An automated receptacle transporting system moves the sample vessels from one station to the next. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte, and, in one embodiment, a method for real-time monitoring of the amplification process.Type: GrantFiled: March 10, 2006Date of Patent: December 24, 2013Assignee: Gen-Probe IncorporatedInventors: James P. Light, II, James M. Carrick
-
Publication number: 20130211286Abstract: Provided herein is technology relating to collecting and preparing samples. For example, the technology relates particularly, but not exclusively, to devices, systems, and kits that allow a subject to collect and prepare a sample for analysis.Type: ApplicationFiled: August 16, 2012Publication date: August 15, 2013Applicant: EXACT SCIENCES CORPORATIONInventors: Graham P. Lidgard, Michael J. Domanico, Keith Fourrier, James P. Light, II, Scott Castanon, Keith Kopitzke
-
Publication number: 20120285900Abstract: Provided herein is technology relating to filtration and particularly, but not exclusively, to filters and methods for filtering by means of centrifugation.Type: ApplicationFiled: May 11, 2012Publication date: November 15, 2012Applicant: EXACT SCIENCES CORPORATIONInventors: Michael J. Domanico, James P. Light, II, Keith Koptizke, John Zeis
-
Publication number: 20120288957Abstract: Provided herein is technology relating to processing and preparing samples and particularly, but not exclusively, to methods, systems, and kits for removing assay inhibitors from samples comprising nucleic acids.Type: ApplicationFiled: May 11, 2012Publication date: November 15, 2012Applicant: Exact Sciences CorporationInventors: Janelle J. Bruinsma, Hemanth D. Shenoi, Michael J. Domanico, James P. Light, II
-
Publication number: 20120288868Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.Type: ApplicationFiled: May 11, 2012Publication date: November 15, 2012Applicant: EXACT SCIENCES CORPORATIONInventors: Janelle J. Bruinsma, Michael J. Domanico, Graham P. Lidgard, Hongzhi Zou, William G. Weisburg, Hemanth D. Shenoi, James P. Light, II
-
Publication number: 20120262260Abstract: Provided herein is technology relating to processing samples. In particular, the technology provides articles of manufacture, apparatuses, and methods related to purifying an analyte from a sample matrix using magnetic particles.Type: ApplicationFiled: April 18, 2011Publication date: October 18, 2012Applicant: EXACT SCIENCES CORPORATIONInventors: James P. Light, II, Daniel C. Miller