Patents by Inventor James P. Nataro

James P. Nataro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vaccine
    Patent number: 10166279
    Abstract: A mutant of an E coli heat-stable toxin (ST) having the following wild-type sequence: NSSNYCCELCCNPACTGCY wherein the mutant comprises a mutation selected from the group consisting of: A14H, A14T and N12T.
    Type: Grant
    Filed: February 20, 2014
    Date of Patent: January 1, 2019
    Assignees: Bergen Teknologioverføring, The Administrators of the Tulane Educational Fund
    Inventors: Pål Puntervoll, Halvor Sommerfelt, John Clements, James P. Nataro, Weiping Zhang, Arne M. Taxt
  • Vaccine
    Publication number: 20160220654
    Abstract: A mutant of an E coli heat-stable toxin (ST) having the following wild-type sequence: NSSNYCCELCCNPACTGCY wherein the mutant comprises a mutation selected from the group consisting of: A14H, A14T and N12T.
    Type: Application
    Filed: February 20, 2014
    Publication date: August 4, 2016
    Inventors: Pål Puntervoll, Halvor Sommerfelt, John Clements, James P. Nataro, Weiping Zhang, Arne M. Taxt
  • Antibodies having binding specificity to ShET2, an enterotoxin of Shigella flexneri 2A
    Patent number: 5686580
    Abstract: Substantially pure enterotoxins of Shigella flexneri 2a are described, along with a method for obtaining the same, antibodies having binding specificity to the enterotoxins and a method for use of the enterotoxins to develop a non-reactogenic Shigella flexneri 2a vaccine candidate.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: November 11, 1997
    Assignee: University of Maryland at Baltimore
    Inventors: Alessio Fasano, Myron M. Levine, James P. Nataro, Fernando Noriega
  • Isolated DNA molecule encoding SHET1 of Shigella flexneri 2a and mutant Shigella flexneri 2a
    Patent number: 5589380
    Abstract: Substantially pure enterotoxins of Shigella flexneri 2a are described, along with a method for obtaining the same, antibodies having binding specificity to the enterotoxins and a method for use of the enterotoxins to develop a non-reactogenic Shigella flexneri 2a vaccine candidate.
    Type: Grant
    Filed: November 30, 1994
    Date of Patent: December 31, 1996
    Assignee: University of Maryland at Baltimore
    Inventors: Alessio Fasano, Myron M. Levine, James P. Nataro, Fernando Noriega
  • Isolated DNA molecule encoding ShET2 of Shigella flexneri 2a
    Patent number: 5468639
    Abstract: Substantially pure enterotoxins of Shigella flexneri 2a are described, along with a method for obtaining the same, antibodies having binding specificity to the enterotoxins and a method for use of the enterotoxins to develop a non-reactogenic Shigella flexneri 2a vaccine candidate.
    Type: Grant
    Filed: December 2, 1993
    Date of Patent: November 21, 1995
    Assignee: University of Maryland at Baltimore
    Inventors: Alessio Fasano, Myron M. Levine, James P. Nataro, Fernando Noriega