Patents by Inventor James P. Wepsiec

James P. Wepsiec has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Separation of 5-nitroquinoline and 8-nitroquinoline
    Patent number: 6268500
    Abstract: The present invention relates to a process for preparing 5-nitroquinoline hydrohalide comprising: (A) heating a slurry comprising a mixture of nitroquinoline position isomer hydrohalide salts in wet dimethylformamide to form a solution; (B) cooling the solution of Step (A) until a precipitate comprising 5-nitroquinoline hydrohalide is formed; and (C) collecting the precipitate.
    Type: Grant
    Filed: January 9, 1998
    Date of Patent: July 31, 2001
    Assignee: Eli Lilly and Company
    Inventors: Thomas J. Kress, James P. Wepsiec
  • 5.alpha.-reductase inhibitors
    Patent number: 6150375
    Abstract: A series of benzoquinolin-3-ones are pharmaceuticals effective in treating conditions consequent on both Type I and Type II 5.alpha.-reductase.
    Type: Grant
    Filed: December 11, 1998
    Date of Patent: November 21, 2000
    Assignee: Eli Lilly and Company
    Inventors: James E. Audia, Loretta A. McQuaid, Blake L. Neubauer, Vincent P. Rocco, Kevin L. Haehl, Thomas J. Kress, James P. Wepsiec
  • Process for preparation of benzo[f]quinolinones
    Patent number: 5578724
    Abstract: A series of benzoquinolin-3-ones are pharmaceuticals effective in treating conditions consequent on both Type I and Type II 5.alpha.-reductase and their preparation is disclosed.
    Type: Grant
    Filed: September 20, 1994
    Date of Patent: November 26, 1996
    Assignee: Eli Lilly and Company
    Inventors: Kevin L. Haehl, Thomas J. Kress, James P. Wepsiec
  • 4-amino-6-iodo-hexahydrobenz(cd)indoles
    Patent number: 5039820
    Abstract: 4-Amino-6-iodo-1,2,2a,3,4,5-hexahydrobenz[ cd]indoles are useful intermediates to 4-amino-1,3,4,5-tetrahydrobenz [cd]indoles containing aminocarbonyl or alkoxycarbonyl substituents in the 6-position which are useful for the treatment of various disorders of the central nervous system.
    Type: Grant
    Filed: February 26, 1990
    Date of Patent: August 13, 1991
    Assignee: Eli Lilly and Company
    Inventors: Thomas J. Kress, James P. Wepsiec