Patents by Inventor James Parakka
James Parakka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20180015120Abstract: Polymers having the formula R(LE)x wherein R is a polymeric core having a number average molecular weight of from 5000 to 7,000,000 daltons and having x endgroups, E is an endgroup covalently linked to polymeric core R by linkage L, L is a divalent oligomeric chain, having at least 5 identical repeat units, capable of self-assembly with L chains on adjacent molecules of the polymer, and the moieties (LE)x in the polymer may be the same as or different from one another. Design of monomers, oligomers, or other reactive structures otherwise analogous to known Self Assembled Monolayers but with at least one reactive chemical group capable of binding them to the terminus of a polymer, so that the thiol-free SAM analogue becomes the self-assembling surface modifying endgroup of that polymer. Use of the polymer to fabricate a configured article from the surface-modified polymer or a coating or topical treatment on an article made from another material.Type: ApplicationFiled: August 10, 2017Publication date: January 18, 2018Inventors: Robert S. WARD, Keith R. McCREA, James Parakka, Shanger Wang, Yuan Tian
-
Patent number: 9387281Abstract: A composition comprising at least one polymer having the structure A-B-A?, wherein A and A? may be the same or different and each is a degradable polyester component and wherein B is the reaction product resulting from the reaction between a diol, having one or more pendant oligomeric or polymeric groups, and A and A?. Additionally, a bioresorbable patch comprising: (a) an adhesion barrier component comprising the composition in the form of a film; and (b) an adhesive component comprising (i) at least one synthetic adhesive polymer and/or (ii) at least one polysaccharide. Also, a method of wound healing, comprising administering the composition or apply the patch to a patient.Type: GrantFiled: October 20, 2011Date of Patent: July 12, 2016Assignee: DSM IP ASSETS B.V.Inventors: James Parakka, Ananth Iyer
-
Patent number: 9181401Abstract: Amphiphilic biomimetic phosphorylcholine-containing silicone compounds for use in both topical and internal applications as components in biomedical devices. The silicone compounds, which include zwitterionic phosphorylcholine groups, may be polymerizable or non-polymerizable. Specific examples of applications include use as active functional components in ophthalmic lenses, ophthalmic lens care solutions, liquid bandages, wound dressings, and lubricious and anti-thrombogenic coatings.Type: GrantFiled: June 7, 2010Date of Patent: November 10, 2015Assignee: DSM IP ASSETS B.V.Inventors: James Parakka, Ananth V. Iyer, Anfeng Wang, Xuwei Jiang, Yuan Tian, Robert Ward
-
Patent number: 9086527Abstract: Silicone-containing monomer of formula (I); wherein said silicone-containing monomer comprises a silicone-containing moiety and an oxazolidinone moiety and wherein R is a silicone-containing moiety, and R1 may be an H, wherein A represents the oxazolidinone ring of the oxazolidinone moiety and R2 is a divalent C1-25 alkylene or C6-30 arylalkylene. The monomer is used for the preparation of a composition for use in manufacturing of ophthalmic lenses potentially with anti-infective properties. Also, methods of making the present monomers are described.Type: GrantFiled: December 17, 2013Date of Patent: July 21, 2015Assignee: DSM IP ASSETS B.V.Inventors: James Parakka, Ananth Iyer, Durgaprasad Chalasani, Li Li
-
Publication number: 20140206830Abstract: Silicone-containing monomer of formula (I); wherein said silicone-containing monomer comprises a silicone-containing moiety and an oxazolidinone moiety and wherein R is a silicone-containing moiety, and R1 may be an H, wherein A represents the oxazolidinone ring of the oxazolidinone moiety and R2 is a divalent C1-25 alkylene or C6-30 arylalkylene. The monomer is used for the preparation of a composition for use in manufacturing of ophthalmic lenses potentially with anti-infective properties. Also, methods of making the present monomers are described.Type: ApplicationFiled: December 17, 2013Publication date: July 24, 2014Inventors: James Parakka, Ananth Iyer, Durgaprasad Chalasani, Li Li
-
Publication number: 20140037711Abstract: The instant invention relates to a composition comprising at least one polymer having the structure A-B-A?, wherein A and A? may be the same or different and each is a degradable polyester component and wherein B is the reaction product resulting from the reaction between a diol, having one or more pendant oligomeric or polymeric groups, and A and A?. Additionally, the invention also relates to the development of a bioresorbable patch comprising: (a) an adhesion barrier component comprising a composition according to the invention in the form of a film; and (b) an adhesive component comprising: (i) at least one synthetic adhesive polymer; and/or (ii) at least one polysaccharide. The present invention provides a method of wound healing, comprising administering the composition or patch.Type: ApplicationFiled: October 20, 2011Publication date: February 6, 2014Applicant: DSM IP ASSETS B.V.Inventors: James Parakka, Ananth Iyer
-
Patent number: 8344090Abstract: Methods for preparing functionalized polyvinylpyrrolidones with polymerizable functions. Also, amphipathic polydimethylsiloxane-PVP block copolymers, such as and (meth)acrylated and (meth)acrylamide-functionalized polyvinylpyrrolidone compounds, such as The block copolymers are useful as biomaterial components in biomedical devices. They provide improved wettability, lubricity, and material compatibility to the biomedical device, e.g., ophthalmic lenses.Type: GrantFiled: December 14, 2011Date of Patent: January 1, 2013Assignee: DSM IP Assets B.V.Inventors: James Parakka, Keith R. McCrea, Robert S. Ward
-
Publication number: 20120136087Abstract: Amphiphilic biomimetic phosphorylcholine-containing silicone compounds for use in both topical and internal applications as components in biomedical devices. The silicone compounds, which include zwitterionic phosphorylcholine groups, may be polymerizable or non-polymerizable. Specific examples of applications include use as active functional components in ophthalmic lenses, ophthalmic lens care solutions, liquid bandages, wound dressings, and lubricious and anti-thrombogenic coatings.Type: ApplicationFiled: June 7, 2010Publication date: May 31, 2012Applicant: DSM IP Assets B.V.Inventors: James Parakka, Ananth V. Iyer, Anfeng Wang, Xuwei Jiang, Yuan Tian, Robert Ward
-
Patent number: 8153728Abstract: Methods for preparing functionalized polyvinylpyrrolidones with polymerizable functions. Also, amphipathic polydimethylsiloxane-PVP block copolymers, such as and (meth)acrylated and (meth)acrylamide-functionalized polyvinylpyrrolidone compounds, such as The block copolymers are useful as biomaterial components in biomedical devices. They provide improved wettability, lubricity, and material compatibility to the biomedical device, e.g., ophthalmic lenses.Type: GrantFiled: March 13, 2008Date of Patent: April 10, 2012Assignee: DSM IP Assets B.V.Inventors: James Parakka, Keith R. McCrea, Robert S. Ward
-
Publication number: 20120083573Abstract: Methods for preparing functionalized polyvinylpyrrolidones with polymerizable functions. Also, amphipathic polydimethylsiloxane-PVP block copolymers, such as and (meth)acrylated and (meth)acrylamide-functionalized polyvinylpyrrolidone compounds, such as The block copolymers are useful as biomaterial components in biomedical devices. They provide improved wettability, lubricity, and material compatibility to the biomedical device, e.g., ophthalmic lenses.Type: ApplicationFiled: December 14, 2011Publication date: April 5, 2012Inventors: James PARAKKA, Keith R. McCrea, Robert S. Ward
-
Publication number: 20110124772Abstract: Polymers with non-leaching antimicrobial activity and their use as surface coatings or bulk resins for medical devices. The antimicrobial polymers are prepared with antimicrobial moieties covalently bonded to a polymer chain end or to a polymer backbone at a side chain end. The antimicrobial moiety-containing endgroups include surface active (or surface assembling) moieties which promote enrichment of antimicrobial endgroups at the polymer surface and thus formation of an antimicrobially active surface. Polymers with built-in antimicrobial endgroups can be used as bulk resins, as antimicrobial additives, or as infection preventative coatings in the manufacture of medical devices (e.g., catheters, vascular access devices, peripheral lines, IV sites, drains, gastric feeding and tubes, and other implantable devices).Type: ApplicationFiled: May 26, 2009Publication date: May 26, 2011Applicant: DSM IP Assets B.V.Inventors: Shanger Wang, Robert S. Ward, Yuan Tian, Li Li, Keith Mccrea, James Parakka, Robert L. Jones, JR.
-
Publication number: 20100099829Abstract: Methods for preparation of functionalized polyvinylpyrrolidone with polyme?zabl? functions and amphipathic polydimethylsiloxane-PVP block copolymers A (meth)acrylated polyvinylpyrrolidone compound and a (meth)acrylamide-functionalized polyvinylpyrrolidone structures are disclosed The block copolymers are useful as biomaterial components in biomedical devices They provide improved wettability, lubricity, and material compatibility to the biomedical device, e g, ophthalmic lensesType: ApplicationFiled: March 13, 2008Publication date: April 22, 2010Applicant: The Polymer Technology Group IncorporatedInventor: James PARAKKA
-
Patent number: 7679078Abstract: Optoelectronic materials are provided that are bistable organic tautomeric compositions that intraconvert dithio or diseleno carbamate esters and cyclic 1,3-dithia- or -diselena-2-iminium salts of ?-conjugated bis-anthracenyl compounds. Specifically disclosed are compounds having the formula: where X is sulfur or selenium; where the R and R1 groups are alkyl or alkyl that together form a ring of carbon atoms; where An is the anion of a strong acid; and where the Z element is a chiral ring-completing system of atoms that changes chirality on tautomerization. These molecules are in themselves molecular-sized optoelectronic switching devices.Type: GrantFiled: March 10, 2005Date of Patent: March 16, 2010Assignee: California Molecular Electronics CorporationInventors: Robert R. Schumaker, James J. Marek, Jr., James Parakka
-
Publication number: 20070265460Abstract: The present invention relates to a process comprising the steps of reacting in the presence of a hydrosilylation catalyst, a first reaction mixture comprising a free radical reactive compound and a silicon containing compound to form a silicon substituted glyceryl (meth)acrylate.Type: ApplicationFiled: July 25, 2007Publication date: November 15, 2007Inventors: Shivkumar Mahadevan, Robert Ward, Shanger Wang, James Parakka, Yuan Tian, Frank Molock
-
Publication number: 20060229423Abstract: Synthesis and purification of mono and narrow disperse monofunctional polydimethylsiloxane methacrylate derivatives with different molecular weights are disclosed.Type: ApplicationFiled: March 16, 2006Publication date: October 12, 2006Inventors: James Parakka, Yuan Tian, Robert Ward, Wang Shanger
-
Publication number: 20060202193Abstract: Optoelectronic materials are provided that are bistable organic tautomeric compositions that intraconvert dithio or diseleno carbamate esters and cyclic 1,3-dithia- or -diselena-2-iminium salts of ?-conjugated bis-anthracenyl compounds. Specifically disclosed are compounds having the formula: where X is sulfur or selenium; where the R and R1 groups are alkyl or alkyl that together form a ring of carbon atoms; where An is the anion of a strong acid; and where the Z element is a chiral ring-completing system of atoms that changes chirality on tautomerization. These molecules are in themselves molecular-sized optoelectronic switching devices.Type: ApplicationFiled: March 10, 2005Publication date: September 14, 2006Inventors: Robert Schumaker, James Marek, James Parakka
-
Publication number: 20060047134Abstract: The present invention relates to a process comprising the steps of reacting in the presence of a hydrosilylation catalyst, a first reaction mixture comprising a free radical reactive compound and a silicon containing compound to form a silicon substituted glyceryl (meth)acrylate.Type: ApplicationFiled: August 25, 2004Publication date: March 2, 2006Inventors: Frank Molock, Shivkumar Mahadevan, Robert Ward, Shanger Wang, James Parakka, Yuan Tian
-
Publication number: 20050282997Abstract: Polymers whose surfaces are modified by endgroups that include amphipathic surface-modifying moieties. An amphipathic endgroup of a polymer molecule is an endgroup that contains at least two moieties of significantly differing composition, such that the amphipathic endgroup spontaneously rearranges its positioning in a polymer body to position the moiety on the surface of the body, depending upon the composition of the medium with which the body is in contact, when that re-positioning causes a reduction in interfacial energy. An example of an amphipathic surface-modifying endgroup is one that has both a hydrophobic moiety and a hydrophilic moiety in a single endgroup. For instance, a hydrophilic poly(ethylene oxide) terminated with a hydrophilic hydroxyl group is not surface active in air when the surface-modifying endgroup is bonded to a more hydrophobic base polymer.Type: ApplicationFiled: August 26, 2005Publication date: December 22, 2005Inventors: Robert Ward, Keith McCrea, Yuan Tian, James Parakka