Patents by Inventor James Patrick MORRISON

James Patrick MORRISON has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Carboxyesterase biocatalysts
    Patent number: 12331327
    Abstract: The present disclosure provides engineered carboxyesterase enzymes that have the ability to catalyze amide bond formation. Also provided are polynucleotides encoding the carboxyesterase enzymes, host cells capable of expressing the engineered carboxyesterase enzymes, and methods of using the engineered carboxyesterase enzymes to make commercially valuable amides. Also provided are amides that are made using the engineered carboxyesterase enzymes.
    Type: Grant
    Filed: October 13, 2022
    Date of Patent: June 17, 2025
    Assignee: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
    Inventors: Kristin K. Brown, Brent M. Dorr, Douglas E. Fuerst, Katherine Joyce Honicker, Lydia Sanchez Jordan, James Patrick Morrison, Nikolay V. Plotnikov, Markus Schober, Rama Voladri
  • Enzymatic Modification of Saponins
    Publication number: 20250163486
    Abstract: Methods for the enzymatic modification of saponins produced in plant cell culture, products made thereby, uses of said products and also to other associated aspects. The saponins may be obtained from plant cell culture extracts of Quillaja species, such as extracts of Quillaja saponaria Molina.
    Type: Application
    Filed: December 2, 2024
    Publication date: May 22, 2025
    Applicant: GlaxoSmithKline Biologicals SA
    Inventors: Murray BROWN, Edward CHAPMAN, Andrew John COLLIS, Douglas E. FUERST, Joseph HOSFORD, Christopher M. MACDERMAID, Grégory MATHY, James Patrick MORRISON
  • CARBOXYESTERASE BIOCATALYSTS
    Publication number: 20230193227
    Abstract: The present disclosure provides engineered carboxyesterase enzymes that have the ability to catalyze amide bond formation. Also provided are polynucleotides encoding the carboxyesterase enzymes, host cells capable of expressing the engineered carboxyesterase enzymes, and methods of using the engineered carboxyesterase enzymes to make commercially valuable amides. Also provided are amides that are made using the engineered carboxyesterase enzymes.
    Type: Application
    Filed: October 13, 2022
    Publication date: June 22, 2023
    Inventors: Kristin K. Brown, Brent M. Dorr, Douglas E. Fuerst, Katherine Joyce Honicker, Lydia Sanchez Jordan, James Patrick Morrison, Nikolay V. Plotnikov, Markus Schober, Rama Voladri
  • Carboxyesterase biocatalysts
    Patent number: 11535833
    Abstract: The present disclosure provides engineered carboxyesterase enzymes that have the ability to catalyze amide bond formation. Also provided are polynucleotides encoding the carboxyesterase enzymes, host cells capable of expressing the engineered carboxyesterase enzymes, and methods of using the engineered carboxyesterase enzymes to make commercially valuable amides. Also provided are amides that are made using the engineered carboxyesterase enzymes.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: December 27, 2022
    Assignee: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
    Inventors: Kristin K. Brown, Brent M. Dorr, Douglas E. Fuerst, Katherine Joyce Honicker, Lydia Sanchez Jordan, James Patrick Morrison, Nikolay V. Plotnikov, Markus Schober, Rama Voladri
  • CARBOXYESTERASE BIOCATALYSTS
    Publication number: 20210115417
    Abstract: The present disclosure provides engineered carboxyesterase enzymes that have the ability to catalyze amide bond formation. Also provided are polynucleotides encoding the carboxyesterase enzymes, host cells capable of expressing the engineered carboxyesterase enzymes, and methods of using the engineered carboxyesterase enzymes to make commercially valuable amides. Also provided are amides that are made using the engineered carboxyesterase enzymes.
    Type: Application
    Filed: December 13, 2018
    Publication date: April 22, 2021
    Inventors: Kristin K. BROWN, Brent M. DORR, Douglas E. FUERST, Katherina Joyce HONICKER, Lydia Sanchez JORDAN, James Patrick MORRISON, Nikolay V. PLOTNIKOV, Markus SCHOBER, Rama VOLADRI