Patents by Inventor James Pearce

James Pearce has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12649699
    Abstract: Genetically engineered bacteria which express RNAs or proteins that produce ammonia upon decreases in phosphate concentrations are disclosed.
    Type: Grant
    Filed: January 31, 2025
    Date of Patent: June 9, 2026
    Assignee: SWITCH BIOWORKS, INC.
    Inventors: Caroline Kukolj, Tim Schnabel, Timothy Lyndon Haskett, Gregory Alexander Knauf, Tomasz Zajkowski, Elizabeth Leigh Ordeman, Niklaus Hoyt Evitt, James Pearce, Sandipan Samaddar, Daniel Torres Naylor, Hsiao-Han Lin, Alexis Makena Chun
  • Publication number: 20260150847
    Abstract: Disclosed herein are biocontrol compositions against plant fungal pathogens and methods of use thereof for the prevention or reduction of crop loss or food spoilage. The biocontrol composition may comprise at least one microbe, or a secondary metabolite of the at least one microbe, with anti-fungal or anti-pathogenic activity. The methods and compositions disclosed herein may prevent or inhibit the growth of a variety of different pathogens, including pathogens of the genus Penicillium. The biocontrol compositions may be applied to a plant, a seed, or a produce thereof or to a packaging material used to transport or store the produce.
    Type: Application
    Filed: December 19, 2023
    Publication date: June 4, 2026
    Applicant: NIHON NOHYAKU CO., LTD.
    Inventors: Veronica GARCIA, Sofia ANDRIKOPOULOS, Jesina FROLAND, Kelly TRINIDAD, Christy PIAMONTE, James PEARCE, Jamie BACHER
  • Patent number: 12570993
    Abstract: Provided are compositions and methods relating to gene and/or protein mutations in transgenic or non-transgenic plants. In certain embodiments, the disclosure relates to mutations in the protoporphyrinogen IX (PPX) gene. In some embodiments the disclosure relates to plants that are herbicide resistant.
    Type: Grant
    Filed: September 7, 2021
    Date of Patent: March 10, 2026
    Assignees: CIBUS US LLC, CIBUS EUROPE B.V.
    Inventors: Gregory F.W. Gocal, Peter R. Beetham, Aura Estela Gonzalez Schopke, Sarah Dumm, James Pearce, Christian Schopke, Keith A. Walker
  • Publication number: 20250243130
    Abstract: Genetically engineered bacteria which express RNAs or proteins that produce ammonia upon decreases in phosphate concentrations are disclosed.
    Type: Application
    Filed: January 31, 2025
    Publication date: July 31, 2025
    Inventors: Caroline Kukolj, Tim Schnabel, Timothy Lyndon Haskett, Gregory Alexander Knauf, Tomasz Zajkowski, Elizabeth Leigh Ordeman, Niklaus Hoyt Evitt, James Pearce, Sandipan Samaddar, Daniel Torres Naylor, Hsiao-Han Lin, Alexis Makena Chun
  • Patent number: 12331303
    Abstract: The invention provides to improved methods for the modification of genes in plant cells, and plants and seeds derived therefrom. More specifically, the invention relates to the increased efficiency of targeted gene mutation by combining gene repair oligonucleotides with approaches that enhance the availability of components of the target cell gene repair mechanisms.
    Type: Grant
    Filed: August 22, 2022
    Date of Patent: June 17, 2025
    Assignees: CIBUS US LLC, CIBUS EUROPE B.V.
    Inventors: Peter R. Beetham, Gregory F. W. Gocal, Christian Schopke, Noel Joy Sauer, James Pearce, Rosa E. Segami, Jerry Mozoruk
  • Publication number: 20250066805
    Abstract: Provided herein include methods and compositions for effecting a targeted genetic change in DNA in a cell. Certain aspects and embodiments relate to improving the efficiency of the targeting of modifications to specific locations in genomic or other nucleotide sequences. As described herein, nucleic acids which direct specific changes to the genome may be combined with various approaches to enhance the availability of components of the natural repair systems present in the cells being targeted for modification.
    Type: Application
    Filed: October 25, 2024
    Publication date: February 27, 2025
    Applicants: CIBUS US LLC, Cibus Europe B.V.
    Inventors: Peter R. BEETHAM, Gregory F.W. GOCAL, Christian SCHOPKE, Noel SAUER, James PEARCE, Rosa E. SEGAMI, Jerry MOZORUK
  • Publication number: 20240084316
    Abstract: Provided herein include methods and compositions for effecting a targeted genetic change in DNA in a cell. Certain aspects and embodiments relate to improving the efficiency of the targeting of modifications to specific locations in genomic or other nucleotide sequences. As described herein, nucleic acids which direct specific changes to the genome may be combined with various approaches to enhance the availability of components of the natural repair systems present in the cells being targeted for modification.
    Type: Application
    Filed: September 18, 2023
    Publication date: March 14, 2024
    Applicants: CIBUS US LLC, Cibus Europe B.V.
    Inventors: Peter R. BEETHAM, Gregory F.W. GOCAL, Christian SCHOPKE, Noel SAUER, James PEARCE, Rosa E. SEGAMI, Jerry MOZORUK
  • Publication number: 20230407322
    Abstract: Provided herein include methods and compositions for making targeted changes to a DNA sequence. In various aspects and embodiments, methods and compositions for modifying a DNA sequence in a cell (such as a plant, bacterial, yeast, fungal, algal, or mammalian cell) are provided. In some aspects and embodiments the modification of DNA involves combining gene repair oligonucleotides with approaches that enhance the availability of components of the target cell gene repair mechanisms, such as a DNA cutter.
    Type: Application
    Filed: January 2, 2023
    Publication date: December 21, 2023
    Applicants: CIBUS US LLC, CIBUS EUROPE B.V.
    Inventors: Peter R. BEETHAM, Gregory F.W. GOCAL, Christian SCHOPKE, Noel SAUER, James PEARCE, Rosa E. SEGAMI, Jerry MOZORUK
  • Publication number: 20230313211
    Abstract: The invention provides to improved methods for the modification of genes in plant cells, and plants and seeds derived therefrom. More specifically, the invention relates to the increased efficiency of targeted gene mutation by combining gene repair oligonucleotides with approaches that enhance the availability of components of the target cell gene repair mechanisms.
    Type: Application
    Filed: August 22, 2022
    Publication date: October 5, 2023
    Applicants: CIBUS US LLC, CIBUS EUROPE B.V.
    Inventors: Peter R. BEETHAM, Gregory F.W. GOCAL, Christian SCHOPKE, Noel Joy SAUER, James PEARCE, Rosa E. SEGAMI, Jerry MOZORUK
  • Patent number: 11771029
    Abstract: Disclosed herein are biocontrol compositions against plant fungal pathogens and methods of use thereof for the prevention or reduction of crop loss or food spoilage. The biocontrol composition can comprise at least one microbe with anti-fungal activity or a secondary metabolite of the at least one microbe. The methods can comprise application of the biocontrol composition to a plant, a seed, or a produce thereof or to a packaging material used to transport or store the produce.
    Type: Grant
    Filed: August 11, 2020
    Date of Patent: October 3, 2023
    Assignee: Boost Biomes, Inc.
    Inventors: Robert McBride, Karen Hunt, Jamie Bacher, Veronica Garcia, James Pearce
  • Patent number: 11761011
    Abstract: Provided herein include methods and compositions for effecting a targeted genetic change in DNA in a cell. Certain aspects and embodiments relate to improving the efficiency of the targeting of modifications to specific locations in genomic or other nucleotide sequences. As described herein, nucleic acids which direct specific changes to the genome may be combined with various approaches to enhance the availability of components of the natural repair systems present in the cells being targeted for modification.
    Type: Grant
    Filed: March 22, 2021
    Date of Patent: September 19, 2023
    Assignees: CIBUS US LLC, CIBUS EUROPE B.V.
    Inventors: Peter R. Beetham, Gregory F. W. Gocal, Christian Schopke, Noel Sauer, James Pearce, Rosa E. Segami, Jerry Mozoruk
  • Publication number: 20230141977
    Abstract: The invention provides to improved methods for the modification of genes in plant cells, and plants and seeds derived therefrom. More specifically, the invention relates to the increased efficiency of targeted gene mutation by combining gene repair oligonucleotides with approaches that enhance the availability of components of the target cell gene repair mechanisms.
    Type: Application
    Filed: September 5, 2022
    Publication date: May 11, 2023
    Applicants: CIBUS US LLC, CIBUS EUROPE B.V.
    Inventors: Peter R. BEETHAM, Gregory F.W. GOCAL, Christian SCHOPKE, Noel Joy SAUER, James PEARCE, Rosa E. SEGAMI, Jerry MOZORUK
  • Patent number: 11542515
    Abstract: Provided herein include methods and compositions for making targeted changes to a DNA sequence. In various aspects and embodiments, methods and compositions for modifying a DNA sequence in a cell (such as a plant, bacterial, yeast, fungal, algal, or mammalian cell) are provided. In some aspects and embodiments the modification of DNA involves combining gene repair oligonucleotides with approaches that enhance the availability of components of the target cell gene repair mechanisms, such as a DNA cutter.
    Type: Grant
    Filed: September 16, 2016
    Date of Patent: January 3, 2023
    Assignees: CIBUS US LLC, CIBUS EUROPE B.V.
    Inventors: Peter R. Beetham, Gregory F. W. Gocal, Christian Schopke, Noel Sauer, James Pearce, Rosa E. Segami, Jerry Mozoruk
  • Publication number: 20220298525
    Abstract: Provided are compositions and methods relating to gene and/or protein mutations in transgenic or non-transgenic plants. In certain embodiments, the disclosure relates to mutations in the protoporphyrinogen IX (PPX) gene. In some embodiments the disclosure relates to plants that are herbicide resistant.
    Type: Application
    Filed: September 7, 2021
    Publication date: September 22, 2022
    Applicants: CIBUS US LLC, CIBUS EUROPE B.V.
    Inventors: Gregory F.W. Gocal, Peter R. Beetham, Aura Estela Gonzalez Schopke, Sarah Dumm, James Pearce, Christian Schopke, Keith A. Walker
  • Patent number: 11434494
    Abstract: The invention provides to improved methods for the modification of genes in plant cells, and plants and seeds derived therefrom. More specifically, the invention relates to the increased efficiency of targeted gene mutation by combining gene repair oligonucleotides with approaches that enhance the availability of components of the target cell gene repair mechanisms.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: September 6, 2022
    Assignees: CIBUS US LLC, CIBUS EUROPE B.V.
    Inventors: Peter R. Beetham, Gregory F. W. Gocal, Christian Schopke, Noel Joy Sauer, James Pearce, Rosa E. Segami, Jerry Mozoruk
  • Publication number: 20220264894
    Abstract: Disclosed herein are biocontrol compositions against plant fungal pathogens and methods of use thereof for the prevention or reduction of crop loss or food spoilage. The biocontrol composition may comprise at least one microbe, or a secondary metabolite of the at least one microbe, with anti-fungal or anti-pathogenic activity. The methods and compositions disclosed herein may prevent or inhibit the growth of a variety of different pathogens, including pathogens of the genus Penicillium. The biocontrol compositions may be applied to a plant, a seed, or a produce thereof or to a packaging material used to transport or store the produce.
    Type: Application
    Filed: February 7, 2022
    Publication date: August 25, 2022
    Inventors: Veronica Garcia, Sophia Andrikopoulos, Jensina Froland, Kelly Trinidad, Christy Piamonte, James Pearce, Jamie Bacher
  • Patent number: 11421240
    Abstract: The invention provides to improved methods for the modification of genes in plant cells, and plants and seeds derived therefrom. More specifically, the invention relates to the increased efficiency of targeted gene mutation by combining gene repair oligonucleotides with approaches that enhance the availability of components of the target cell gene repair mechanisms.
    Type: Grant
    Filed: May 13, 2019
    Date of Patent: August 23, 2022
    Assignees: CIBUS US LLC, CIBUS EUROPE B.V.
    Inventors: Peter R. Beetham, Gregory F. W. Gocal, Christian Schopke, Noel Joy Sauer, James Pearce, Rosa E. Segami, Jerry Mozoruk
  • Publication number: 20220256861
    Abstract: Disclosed herein are biocontrol compositions against plant fungal pathogens and methods of use thereof for the prevention or reduction of crop loss or food spoilage.
    Type: Application
    Filed: February 11, 2022
    Publication date: August 18, 2022
    Inventors: Veronica Garcia, Sophia Andrikopoulos, Jensina Froland, Kelly Trinidad, Christy Piamonte, James Pearce, Jamie Bacher, Nathaniel T. Becker, Aleksandra Virag, Amruta J. Bedekar, Elizabeth A. Malinich
  • Patent number: 11111500
    Abstract: Provided are compositions and methods relating to gene and/or protein mutations in transgenic or non-transgenic plants. In certain embodiments, the disclosure relates to mutations in the protoporphyrinogen IX (PPX) gene. In some embodiments the disclosure relates to plants that are herbicide resistant.
    Type: Grant
    Filed: July 23, 2018
    Date of Patent: September 7, 2021
    Assignees: CIBUS US LLC, CIBUS Europe B.V.
    Inventors: Gregory F. W. Gocal, Peter R. Beetham, Aura Estela Gonzalez Schopke, Sarah Dumm, James Pearce, Christian Schopke, Keith A. Walker
  • Publication number: 20210261974
    Abstract: Provided herein include methods and compositions for effecting a targeted genetic change in DNA in a cell. Certain aspects and embodiments relate to improving the efficiency of the targeting of modifications to specific locations in genomic or other nucleotide sequences. As described herein, nucleic acids which direct specific changes to the genome may be combined with various approaches to enhance the availability of components of the natural repair systems present in the cells being targeted for modification.
    Type: Application
    Filed: March 22, 2021
    Publication date: August 26, 2021
    Applicants: CIBUS US LLC, CIBUS EUROPE B.V.
    Inventors: Peter R. BEETHAM, Gregory F.W. GOCAL, Christian SCHOPKE, Noel SAUER, James PEARCE, Rosa E. SEGAMI, Jerry MOZORUK