Abstract: An imaging system and method for imaging a scene using a rolling shutter are described. In an embodiment, the method includes illuminating a scene with first and second illumination light; generating frame signals with a photodetector comprising a plurality of pixels arranged in a plurality of rows, wherein the frame signals are based on light received from the scene with sequentially integrated rows of pixels of the plurality of rows, and wherein a frame signal includes signals from pixels of each of the plurality of rows; and generating images of the scene based on an intensity of the frame signals and the proportion of the first illumination light and the second illumination light emitted onto the scene during the first and second frames, wherein a proportion of the first illumination light and the second illumination light in a first frame is different than in a second frame.

Abstract: Systems and methods for acquiring images of a sample are provided. According to an aspect of the invention, a system includes a first light source that emits first light having a first wavelength as a temporally continuous beam; a second light source that emits second light having a second wavelength as a temporally modulated beam; and a scanning mirror that raster scans the first light across a sample during a raster scan period, and projects a structured light pattern of the second light onto the sample during the raster scan period. A first image of the sample is generated from at least a portion of the first light that is backscattered from the sample during the raster scan period, and a second image of the sample is generated from at least a portion of the second light that is backscattered from the sample during the raster scan period.

Abstract: An imaging system includes an image sensor having an array of sensor pixels, a multi-chromatic illuminator adapted to independently generate a plurality of illumination colors each having a different finite spectral range, and a controller coupled to the image sensor and to the multi-chromatic illuminator. The controller includes logic to time-multiplexing the multi-chromatic illuminator between the illumination colors. Each of the illumination colors independently illuminates for at least a corresponding one of non-overlapping durations of illumination of the illumination colors. The controller includes further logic to acquire chromatic sub-images with the image sensor and combine the chromatic sub-images into a composite color image. Each of the chromatic sub-images is acquired during a different one of the non-overlapping durations of illumination.

Abstract: Endoscopic systems including multimode optical fibers for and methods of interrogating a portion of a body are described. In an example, the endoscopic system includes a multimode optical fiber, a coherent light source positioned to emit coherent light through the multimode optical fiber, and a photodetector positioned to absorb scattered coherent light emitted from the multimode optical fiber and configured to generate a speckled light signal based on the scattered coherent light. In an example, the endoscopic system includes a controller configured to analyze the speckled light signal with machine learning classifier and to generate an identification signal indicative of a characteristic of the portion of the body.

Abstract: An imaging system includes an image sensor having an array of sensor pixels, a multi-chromatic illuminator adapted to independently generate a plurality of illumination colors each having a different finite spectral range, and a controller coupled to the image sensor and to the multi-chromatic illuminator. The controller includes logic to time-multiplexing the multi-chromatic illuminator between the illumination colors. Each of the illumination colors independently illuminates for at least a corresponding one of non-overlapping durations of illumination of the illumination colors. The controller includes further logic to acquire chromatic sub-images with the image sensor and combine the chromatic sub-images into a composite color image. Each of the chromatic sub-images is acquired during a different one of the non-overlapping durations of illumination.

Abstract: Systems and methods for acquiring images of a sample are provided. According to an aspect of the invention, a system includes a first light source that emits first light having a first wavelength as a temporally continuous beam; a second light source that emits second light having a second wavelength as a temporally modulated beam; and a scanning mirror that raster scans the first light across a sample during a raster scan period, and projects a structured light pattern of the second light onto the sample during the raster scan period. A first image of the sample is generated from at least a portion of the first light that is backscattered from the sample during the raster scan period, and a second image of the sample is generated from at least a portion of the second light that is backscattered from the sample during the raster scan period.