Patents by Inventor James R. Basilion

James R. Basilion has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PSMA targeted nanobubbles for diagnostic and therapeutic applications
    Patent number: 10434194
    Abstract: A PSMA targeted nanobubble includes a membrane that defines at least one internal void, which includes at least one gas, and at least one PSMA ligand coupled or conjugated to the membrane. The membrane includes at least one lipid and at least one nonionic triblock copolymer that is effective to control the size of the nanobubble without compromising in vitro and in vivo echogenicity of the nanobubble.
    Type: Grant
    Filed: August 30, 2017
    Date of Patent: October 8, 2019
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: James R. Basilion, Agata Exner, Xinning Wang, Christopher Hernandez
  • PSMA TARGETED NANOBUBBLES FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS
    Publication number: 20180064831
    Abstract: A PSMA targeted nanobubble includes a membrane that defines at least one internal void, which includes at least one gas, and at least one PSMA ligand coupled or conjugated to the membrane. The membrane includes at least one lipid and at least one nonionic triblock copolymer that is effective to control the size of the nanobubble without compromising in vitro and in vivo echogenicity of the nanobubble.
    Type: Application
    Filed: August 30, 2017
    Publication date: March 8, 2018
    Inventors: James R. Basilion, Agata Exner