Patents by Inventor James R Brown

James R Brown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5939298
    Abstract: The invention provides pheS polypeptides and DNA (RNA) encoding pheS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pheS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: July 23, 1997
    Date of Patent: August 17, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: James R Brown, Elizabeth J Lawlor, Raymond W Reichard
  • Patent number: 5935816
    Abstract: The invention provides lysS polypeptides and DNA (RNA) encoding lysS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing lysS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: July 23, 1997
    Date of Patent: August 10, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: James R. Brown, Elizabeth J Lawlor, Raymond W Reichard
  • Patent number: 5882892
    Abstract: The invention provides aspS polypeptides and DNA (RNA) encoding aspS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing aspS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: July 23, 1997
    Date of Patent: March 16, 1999
    Assignee: Smithkline Beecham Corporation
    Inventors: James R Brown, Elizabeth J Lawlor, Raymond W Reichard
  • Patent number: 5858720
    Abstract: The invention provides hisS polypeptides and DNA (RNA) encoding hisS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing hisS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: July 23, 1997
    Date of Patent: January 12, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: James R. Brown, Elizabeth J Lawlor, Raymond W Reichard
  • Patent number: 5849555
    Abstract: The invention provides valS polypeptides and DNA (RNA) encoding valS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing valS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: October 17, 1997
    Date of Patent: December 15, 1998
    Assignee: SmithKline Beecham Corporation
    Inventors: James R. Brown, Deborah D. Jaworski, Elizabeth J. Lawlor, Min Wang
  • Patent number: 5444973
    Abstract: Disclosed is a space launch system having a main engine which uses turbopumps to provide fuel and oxidizer to the main engine combustion chamber, and one or more booster engines that use high pressure fuel and/or oxidizer to pressurize the fuel and oxidizer tanks of the booster engine to obtain the pressure differential necessary to drive fuel and oxidizer from the fuel and oxidizer tanks of the booster engine to the combustion chamber of the booster engine.
    Type: Grant
    Filed: December 13, 1993
    Date of Patent: August 29, 1995
    Assignee: United Technologies Corporation
    Inventors: Charles D. Limerick, James R. Brown
  • Patent number: 4971439
    Abstract: A calibration method and apparatus for economical and rapid calibration of a scientific instrument utilizing a monochromator to generate monochromatic light utilizing controllable means for determining the angular position of a light dispersing element in the monochromator and a filter having a narrow absorption band(s) to determine a relationship between the wavelength of the monochromatic light generated by the monochromator and an angular position of the dispersing element so that the dispersing element can be rotated to an exact position for the monochromator to generate a selected wavelength of monochromatic light.
    Type: Grant
    Filed: January 18, 1989
    Date of Patent: November 20, 1990
    Assignee: Beckman Instruments, Inc.
    Inventor: James R. Brown
  • Patent number: 4925363
    Abstract: A roller structure for a rotary machine has a plate that is removably engagable with the outer casing of such rotary machines, a shaft portion attached to the plate and insertable through the outer casing, a bearing mounted for rotation upon the shaft portion, and a selected plurality of shims having different thicknesses engagable upon the shaft portion to adjust the position of the bearing with respect to an inner casing of the rotary machine.
    Type: Grant
    Filed: February 13, 1989
    Date of Patent: May 15, 1990
    Assignee: Westinghouse Electric Corp.
    Inventors: James R. Brown, Rick A. Olson
  • Patent number: 4883782
    Abstract: A thin film catalyst structure is described for use in hydrodesulphurization of gaseous hydrocarbon mixtures. The catalyst is formed starting with an aluminum substrate having an oxide surface layer and thin films of metallic cobalt and molybdenum are sequentially deposited on the aluminum oxide layer. The films of metallic cobalt and molybdenum are calcined and then reduced and sulphided to form a sulphided thin film catalyst structure having improved hydrodesulphurization properties.
    Type: Grant
    Filed: July 5, 1988
    Date of Patent: November 28, 1989
    Assignee: Energy, Mines and Resources-Canada
    Inventors: James R. Brown, Norman S. McIntyre, Darlene D. Johnston
  • Patent number: 4837374
    Abstract: A microreactor is described which is especially designed to analyze small solid samples, such as thin film catalyst. It includes (a) a horizontal tubular reaction vessel for receiving an article for testing, one end of the vessel being closed and the other end being connected to a ball valve end flange, (b) a horizontal shelf within the reaction vessel adapted to receive and support the article for testing, (c) gas inlet means for introducing gas into the vessel, (d) gas outlet means for removing gas from the vessel, (e) sensing means for sensing the temperature within the reaction vessel, (f) means disposed outwardly of the vessel and in heat-conductive relation to the outer surface thereof for heating the vessel, and (g) releaseable gripper means for delivering the article for testing through the ball valve and into the reaction vessel and for releasing the article onto the shelf.
    Type: Grant
    Filed: June 1, 1987
    Date of Patent: June 6, 1989
    Inventors: James R. Brown, Leighton L. Coatsworth, Irold S. Schmidt
  • Patent number: 4779279
    Abstract: The present invention comprises a method and means for stabilizing the frequency difference between the component frequency modes in the beam of a gas laser influenced by Zeeman splitting. Stabilizing the frequency difference makes constant the frequency of the beat signal obtained from heterodyning the component modes. Stabilization is obtained by accurately controlling the difference in frequency between the component frequency modes to provide a selected separation, preferably 250 KHz, with deviation maintained at less than two KHz. The difference in frequencies is controlled independently of the individual frequency or intensity of either of the component frequency modes, or of their relative position within the "Doppler broadened" spectral profile characteristic of the lasing material.
    Type: Grant
    Filed: April 8, 1987
    Date of Patent: October 18, 1988
    Assignee: Beckman Instruments, Inc.
    Inventor: James R. Brown
  • Patent number: 4771599
    Abstract: Fuel for a rocket engine consisting of hydrogen, oxygen and a hydrocarbon is admitted into the combustion zone through an injector whereby the hydrogen and hydrocarbon components are either pre-mixed in the injector or independently delivered and the oxygen is always independently delivered into the combustion zone.
    Type: Grant
    Filed: October 20, 1986
    Date of Patent: September 20, 1988
    Assignee: United Technologies Corporation
    Inventors: James R. Brown, Charles D. Limerick
  • Patent number: 4771600
    Abstract: The invention combines liquid hydrogen with liquid oxygen and a hydrocarbon as the fuels in a tripropellant rocket booster engine.
    Type: Grant
    Filed: October 20, 1986
    Date of Patent: September 20, 1988
    Assignee: United Technologies Corporation
    Inventors: Charles D. Limerick, James R. Brown
  • Patent number: 4732850
    Abstract: A biological indicator is made of a vial which contains a "spore dot", a nutrient solution in a frangible ampoule, and means for positioning the spore dot and for breaking the ampoule to release the nutrient solution when the cap of the vial is fully pressed on. The nutrient solution typically contains a pH indicator to determine whether all active spores on the strip were killed by a sterilization process which takes place prior to breaking the ampoule.
    Type: Grant
    Filed: July 5, 1985
    Date of Patent: March 22, 1988
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: James R. Brown, Steven T. Buglino
  • Patent number: 4682530
    Abstract: An arming trigger unit having a retractable member for selectively retaining or releasing an arming wire of a store which retractable member is, after having been released, retained in its release position by a safety member. Further, such safety member engages a ring portion of the arming wire such that ejection of the ring portion is assisted when the arming wire is released. Such safety member is movable out of the position at which it retains the retractable member to permit a subsequent arming wire to be retained by the retractable member. A method of maintaining an actuating member for a store in a selected position to release an unarmed store by moving a safety member into a position whereat said actuating member is retained in such selected position. Further, the method of installing a store with respect to an aircraft by releasing a safety member to permit an actuating member to captively retain an arming wire.
    Type: Grant
    Filed: May 30, 1986
    Date of Patent: July 28, 1987
    Assignee: Western Gear Corporation
    Inventors: James R. Brown, Gary S. Lane, Wallace H. Larson
  • Patent number: 4488051
    Abstract: Apparatus for establishing a "home" position for a load element driven axially along the lead screw. A position sensor includes a first sensor element attached for axial travel with the load element and a second sensor element attached for rotation with the lead screw. The pair of sensor elements is operatively aligned at a predetermined relative axial and rotational position establishing the "home" position.
    Type: Grant
    Filed: December 28, 1981
    Date of Patent: December 11, 1984
    Assignee: Beckman Instruments, Inc.
    Inventors: James R. Brown, Roy W. Aday, Jr.
  • Patent number: 4437249
    Abstract: A steel plug is inserted into a modern shotgun to convert it into a muzzleloading firearm. The plug is made for use as a breech plug in a single barrel shotgun without modifications to gun. The plug enables the shotgun to be used as a muzzle-loader with black powder and allows conversion of the gun back to its original condition by simply removing the breech plug.
    Type: Grant
    Filed: March 18, 1982
    Date of Patent: March 20, 1984
    Inventors: James R. Brown, Karlis A. Sirons
  • Patent number: 4436994
    Abstract: A photomultiplier detector protection system and method utilizing a negative feedback loop to maintain the photomultiplier detector output below a predetermined output. The feedback loop comprises a comparator responsive to the photomultiplier detector output and also responsive to a predetermined limit signal. The comparator output is applied to a summing amplifier which also receives a voltage adjust signal. The output of the summing amplifier controls the output of a power supply which is in turn applied to the photomultiplier detector.
    Type: Grant
    Filed: December 28, 1981
    Date of Patent: March 13, 1984
    Assignee: Beckman Instruments, Inc.
    Inventors: James G. Van Vliet, James R. Brown
  • Patent number: 4310243
    Abstract: In a spectrophotometer including a photomultiplier tube and an operational amplifier responsive to the current from the photomultiplier tube for generating a DC voltage proportional to light intensity, a method and means for simultaneously compensating for the dark current of the photomultiplier tube and the offset of the operational amplifier so that the output voltage of the operational amplifier is zero volts under dark conditions.
    Type: Grant
    Filed: October 19, 1979
    Date of Patent: January 12, 1982
    Assignee: Beckman Instruments, Inc.
    Inventors: James R. Brown, Allen M. Diamond
  • Patent number: 4300203
    Abstract: A method and means for operating log converter circuits in which the method comprises the steps of sequentially conducting to the input of the log converter circuit signals representing a known transmittance (T) of 100% T, 10% T, 1% T, and 0.1% T, these signals covering the range of operation of the log converter circuit, storing the outputs of the circuit as signals representing an absorbance (A) of 0A, 1A, 2A, and 3A, respectively, conducting to the input of the log converter circuit an unknown signal, and utilizing a microcomputer to perform a linear interpolation of the output of the circuit with the unknown signal applied thereto using the previously stored 0A, 1A, 2A, and 3A signals.
    Type: Grant
    Filed: October 19, 1979
    Date of Patent: November 10, 1981
    Assignee: Beckman Instruments, Inc.
    Inventor: James R. Brown