Abstract: An automated computer-implemented method for reorienting ECT myocardial perfusion images of a heart LV. The method includes receiving variously oriented tomographic images; receiving LV long-axis, LV center and LV axial limits based on the images; receiving the endocardial surface of the LV based on the images; determining a reorientation slice range based on the center and axial limits of the LV; receiving slices (N) within the reorientation slice range; for each slice, determining a center coordinate x[i], y[i] based on the endocardial surface and the area of the slice within a reorientation slice range coordinate system; determining translation ?xi, ?yi and rotation ?x, ?y values based on center coordinates x[i=1 to N], y[i=1 to N] to reorient the LV long axis to the z-axis and its origin of a reference Cartesian coordinate system; and automatically reorienting and realigning the tomographic images based on the translation and rotation values.