Patents by Inventor James R. Hagman

James R. Hagman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biologically active analogs of ACTH and radioimmuno assay therefor
    Patent number: 4415546
    Abstract: A fully steroidogenically active analog of ACTH is disclosed. The analog differs from natural ACTH in that phenylalanine replaces tyrosine in the second position on the peptide chain; and norleucine replaces methionine in the fourth position on the peptide chain. The analog may be iodinated to yield [I]Tyr.sup.2 -Phe.sup.2,Nle.sup.4 -ACTH, which also retains full steroidogenic activity. When labeled with iodine-125 the analog is useful in following steroidogenic processes and also in radioimmunoassays for ACTH.
    Type: Grant
    Filed: May 12, 1981
    Date of Patent: November 15, 1983
    Inventors: Janakiraman Ramachandran, Douglas I. Buckley, Donald H. Yamashiro, James R. Hagman