Abstract: Antibody molecules that specifically bind to APRIL are disclosed. The antibody molecules can be used to treat, prevent, and/or diagnose disorders, such as IgA nephropathy.

Abstract: Antibody molecules that specifically bind to CD138 are disclosed. The antibody molecules can be used to treat, prevent, and/or diagnose disorders, such as multiple myeloma.

Abstract: A vector friendly instruction format and execution thereof. According to one embodiment of the invention, a processor is configured to execute an instruction set. The instruction set includes a vector friendly instruction format. The vector friendly instruction format has a plurality of fields including a base operation field, a modifier field, an augmentation operation field, and a data element width field, wherein the first instruction format supports different versions of base operations and different augmentation operations through placement of different values in the base operation field, the modifier field, the alpha field, the beta field, and the data element width field, and wherein only one of the different values may be placed in each of the base operation field, the modifier field, the alpha field, the beta field, and the data element width field on each occurrence of an instruction in the first instruction format in instruction streams.

Abstract: A computer-implemented method comprising: controlling input of data quantifying damage received by a compressor of a gas turbine engine into a first machine learning algorithm; receiving data quantifying a first operating parameter of the compressor as an output of the first machine learning algorithm; and determining operability of the compressor by comparing the received data quantifying the first operating parameter of the compressor with a threshold.

Abstract: A dual mode exhaust muffler for the engine of a vehicle that may be shifted between a quiet mode and a loud mode. A single muffler, a dual transverse muffler with two independent exhaust flow streams, and a dual transverse muffler with a combined exhaust flow stream embodiments are disclosed. An inlet tube may be a solid wall tube to minimize sound attenuation in the loud mode. The dual transverse muffler embodiments utilize an exhaust flow path that passes out through a reticulated wall of one tube and passes into a reticulated wall of a second tube. A vacuum switch having a two position on/off slide actuator may be used with any of the muffler assemblies.

Abstract: The travel trailer includes a chassis having wheels and a trailer body attached to the chassis. The trailer body includes sidewalls, a front end wall, a rear end wall, a roof, and a floor. The sidewalls, end walls, roof, and floor form an internal living space of the trailer body. A slide-out area is slidably extendable outward from the trailer body. The slide-out area is extendable from a retracted position received substantially within the trailer body to an extended position extended outward from the trailer body. The slide-out area has a roof, sidewalls, a bottom wall, and a front end wall. The front end wall of the slide-out areas is adapted to seal against the trailer body in the retracted position.

Abstract: The travel trailer includes a chassis having wheels and a trailer body attached to the chassis. The trailer body includes sidewalls, a front end wall, a rear end wall, a roof, and a floor. The sidewalls, end walls, roof, and floor form an internal living space of the trailer body. A slide-out area is slidably extendable outward from the trailer body. The slide-out area is extendable from a retracted position received substantially within the trailer body to an extended position extended outward from the trailer body. The slide-out area has a roof, sidewalls, a bottom wall, and a front end wall. The front end wall of the slide-out areas is adapted to seal against the trailer body in the retracted position.

Abstract: The travel trailer includes a chassis having wheels and a trailer hitch for towing the travel trailer. The travel trailer further includes a trailer body attached to the chassis defined by sidewalls, a front end wall, a rear end wall, a roof, and a floor. The sidewalls, end walls, roof, and floor form an internal space of the trailer body. A slide-out area is slidably extendable outward from the trailer body. The slide-out area is extendable from a retracted position received within the trailer body to an extended position extended outward from the trailer body. The slide-out area includes a peaked roof, sidewalls, a bottom wall, and a front end wall. The front end wall includes a flange extending around the perimeter thereof. A sealing gasket is attached to the flange to face the trailer body for sealing against the trailer body in the retracted position of the slide-out area.

Abstract: Top and bottom rails for an outdoor railing system, include a plurality of equally spaced recesses defined in a side of the rails into which spindle ends are fitted. Each of the recesses comprises a multi-sided configuration having an open side defined through an inward edge of the rails so that spindles having a complimentary shaped end can be pressed into the recesses from the sides of the rail.

Abstract: Top and bottom rails for an outdoor railing system, include a plurality of equally spaced recesses defined in a side of the rails into which spindle ends are fitted. Each of the recesses comprises a multi-sided configuration having an open side defined through an inward edge of the rails so that spindles having a complimentary shaped end can be pressed into the recesses from the sides of the rail.

Abstract: The travel trailer includes a chassis having wheels and a trailer hitch for towing the travel trailer. The travel trailer further includes a trailer body attached to the chassis defined by sidewalls, a front end wall, a rear end wall, a roof, and a floor. The sidewalls, end walls, roof, and floor form an internal space of the trailer body. A slide-out area is slidably extendable outward from the trailer body. The slide-out area is extendable from a retracted position received within the trailer body to an extended position extended outward from the trailer body. The slide-out area includes a peaked roof, sidewalls, a bottom wall, and a front end wall. The front end wall includes a flange extending around the perimeter thereof. A sealing gasket is attached to the flange to face the trailer body for sealing against the trailer body in the retracted position of the slide-out area.

Abstract: Top and bottom rails for an outdoor railing system, include a plurality of equally spaced recesses defined in a side of the rails into which spindle ends are fitted. Each of the recesses comprises a multi-sided configuration having an open side defined through an inward edge of the rails so that spindles having a complimentary shaped end can be pressed into the recesses from the sides of the rail.

Abstract: An outdoor railing system has a plurality of spindles attached between upper and lower rails. Each rail includes a plurality of equally spaced recess configurations defined along the length thereof in the inwardly disposed surface for receipt of the spindle ends. Each of the recess configurations includes a first multi-sided recess having a first size and a second multi-sided recess defined within the first multi-sided recess. The second multi-sided recess is of a smaller size than the first recess for anchoring spindles having a correspondingly smaller end size.

Abstract: A weedless fishing lure that does not have an exposed hook until a sufficient tension is placed on the line. The lure comprises a body having an aperture therethrough and at least one channel. A fishing line extends through the aperture and is attached to the shank of a hook. The hook is placed into a channel changing the direction the line runs from that in the aperture so that the line in the channel runs in the opposite direction than that in the aperture. The tip of the hook may be placed in the aperture or in a separate channel. Using this configuration, the hook will be dislodged from the body if sufficient tension is placed on the line.

Abstract: A refrigeration system control apparatus for use with an ice bank for sequentially cycling a refrigerator compressor on and off based on sensed conditions. The system includes a first temperature probe located a first distance from a refrigerator evaporator coil and a second temperature probe located a second, greater distance from the refrigerator evaporator coil. A programmable controller monitors temperature outputs from the first and second temperature probes and turns on and off the refrigerator compressor based upon a rate of change of the temperature difference between the sensed temperatures of the first and second probes.