Patents by Inventor James R. Horning

James R. Horning has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10927368
    Abstract: Methods and compositions are disclosed for introducing molecular switch functionality into a protein affinity reagent to render its binding to a target molecule sensitive to an environmental trigger, such as pH, while maintaining binding affinity to the target molecule. Combinatorial libraries created by the method are also disclosed.
    Type: Grant
    Filed: February 1, 2018
    Date of Patent: February 23, 2021
    Assignee: NORTHERN ILLINOIS RESEARCH FOUNDATION
    Inventor: James R. Horn
  • Publication number: 20180230457
    Abstract: Methods and compositions are disclosed for introducing molecular switch functionality into a protein affinity reagent to render its binding to a target molecule sensitive to an environmental trigger, such as pH, while maintaining binding affinity to the target molecule. Combinatorial libraries created by the method are also disclosed.
    Type: Application
    Filed: February 1, 2018
    Publication date: August 16, 2018
    Inventor: James R. Horn
  • Patent number: 9902948
    Abstract: Methods and compositions are disclosed for introducing molecular switch functionality into a protein affinity reagent to render its binding to a target molecule sensitive to an environmental trigger, such as pH, while maintaining binding affinity to the target molecule. Combinatorial libraries created by the method are also disclosed.
    Type: Grant
    Filed: March 21, 2013
    Date of Patent: February 27, 2018
    Assignee: Board of Trustees of Northern Illinois University
    Inventor: James R. Horn
  • Patent number: 8241443
    Abstract: An electrically initiated security device includes a first energetic sheet, a second energetic sheet, and a corrugated energetic sheet disposed between the first energetic sheet and the second energetic sheet. A first surface of the corrugated energetic sheet defines at least one channel and a second surface of the corrugated energetic sheet defines at least one channel. The electrically initiated security device further includes a first constituent portion disposed in the at least one channel defined by the first surface and a second constituent portion disposed in the at least one channel defined by the second surface. The first constituent portion and the second constituent portion, when mixed, comprise an energetic material.
    Type: Grant
    Filed: July 22, 2009
    Date of Patent: August 14, 2012
    Assignee: Lockheed Martin Corporation
    Inventors: Toby D. Thomas, James R. Horning