Patents by Inventor James R. Howes

James R. Howes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Rotor dovetail hook-to-hook fit
    Patent number: 8167566
    Abstract: A male dovetail for a bucket mounted on a drum rotor for a steam turbine is provided by a tight hook-to-hook fit with the female dovetail of a retaining groove around the periphery of the drum rotor wheel. The tight hook-to-hook fit eliminates the use of loading pins which heretofore have been driven between a base of the male dovetail and a bottom of the retaining groove, a manually intensive operation with the potential to damage the bucket and the rotor.
    Type: Grant
    Filed: December 31, 2008
    Date of Patent: May 1, 2012
    Assignee: General Electric Company
    Inventor: James R. Howes
  • TURBINE ENGINE ROTOR BLADES AND ROTOR WHEELS
    Publication number: 20110158814
    Abstract: A rotor wheel and a rotor blade for use in a turbine engine, the rotor wheel and the rotor blade being configured to comprise a connection formed between a root of the rotor blade and an outer radial portion of the rotor wheel that secures the rotor blade to the rotor wheel during operation of the turbine engine; wherein the connection comprises two or more tangential dovetails.
    Type: Application
    Filed: December 31, 2009
    Publication date: June 30, 2011
    Inventors: Mallikarjun G. Metri, Robert J. Bracken, James R. Howes, Mohamed Kamran
  • ROTOR DOVETAIL HOOK-TO-HOOK FIT
    Publication number: 20100166557
    Abstract: A male dovetail for a bucket mounted on a drum rotor for a steam turbine is provided by a tight hook-to-hook fit with the female dovetail of a retaining groove around the periphery of the drum rotor wheel. The tight hook-to-hook fit eliminates the use of loading pins which heretofore have been driven between a base of the male dovetail and a bottom of the retaining groove, a manually intensive operation with the potential to damage the bucket and the rotor.
    Type: Application
    Filed: December 31, 2008
    Publication date: July 1, 2010
    Inventor: James R. Howes
  • BMPR1A involvement in juvenile polyposis
    Publication number: 20030072758
    Abstract: Familial juvenile polyposis is an autosomal dominant disease characterized by a predisposition to hamartomatous polyps and gastrointestinal cancer. The present invention shows that JP families carry germline mutations in BMPR1A, a gene located at 10q22-23. Methods and compositions for the detection and amelioration of FJP and gastrointestinal tumors are provided.
    Type: Application
    Filed: May 21, 2002
    Publication date: April 17, 2003
    Inventor: James R. Howe
  • Method of diagnosing juvenile polyposis (JP)
    Patent number: 6423491
    Abstract: Familial juvenile polyposis is an autosomal dominant disease characterized by a predisposition to hamartomatous polyps and gastrointestinal cancer. The present invention shows that JP families carry germline mutations in SMAD4/DPC4, a gene on chromosome 18q21.1. The mutant SMAD4 proteins are truncated at the carboxyl-terminus and lack sequences required for normal function. Methods and compositions for the detection and amelioration of FJP and gastrointestinal tumors are provided.
    Type: Grant
    Filed: May 13, 1999
    Date of Patent: July 23, 2002
    Assignee: University of Iowa Research Foundation
    Inventors: James R. Howe, Lauri A. Aaltonen