Abstract: A Thermal Luminescence Water Monitor system and method for real-time remote sensing and identification of chemical and biological materials (CBMs) in a liquid source, comprising an irradiation component having a microwave radiation source tuned to water's vibration-rotation exciting energy, a glass cell for holding a liquid sample contained within a sealed chamber for its irradiation and concomitant liberation of thermal luminescence, a spectrometer analysis component for collecting and processing thermal luminescence emissions, a neural network component for filtering thermal luminescence difference-spectra components and pattern recognition of predetermined CBMs to determine their presence in the liquid source.