Abstract: The present invention relates to compositions and methods for inducing an adaptive immune response against Hepatitis C virus (HCV) in a subject. In some embodiments, the present invention provides a composition comprising a nucleoside-modified nucleic acid molecule encoding a HCV antigen, adjuvant, or a combination thereof. For example, in some embodiments, the composition comprises a vaccine comprising a nucleoside-modified nucleic acid molecule encoding a HCV antigen, adjuvant, or a combination thereof.

Abstract: A propelling system for propelling a fisherman's float through the water while fishing. The propelling system includes a frame assembly having a plurality of strap members. Each of the strap members is designed for selectively engaging the floatation device whereby the strap members are for securing the frame assembly to the floatation device. A propelling assembly is coupled to the frame assembly. The propelling assembly designed for propelling the flotation device along the top of the water when a fisherman is positioned in the floatation device. At least one rod member is coupled to the frame member. The rod member is designed for holding a fishing rod. The rod member is designed for being positioned proximate the fisherman whereby the rod member facilitates access to the fishing rod by the fisherman when the fisherman is positioned in the floatation device.

Abstract: A method of measuring and indicating a level of natural gas fuel in a storage tank of a motor vehicle, comprising the steps of determining a temperature of the natural gas, determining a pressure of the natural gas, retrieving from a look-up table, responsive to the determined temperature and pressure, a signal representative of a percentage that the tank is full of the natural gas, determining a gauge command responsive to the signal, and driving the gauge according to the determined command.