Abstract: A temporary aortic occlusion device is disclosed, having an expandable locator portion and an expandable occlusion portion. The expandable locator portion assists a user in determining whether the distal end of the device has been advanced within a patient's aorta, and the occlusion portion is expanded to occlude the patient's aorta, preferably below the renal arteries.

Abstract: A temporary aortic occlusion device is disclosed, having an expandable locator portion and an expandable occlusion portion. The expandable locator portion assists a user in determining whether the distal end of the device has been advanced within a patient's aorta, and the occlusion portion is expanded to occlude the patient's aorta, preferably below the renal arteries.

Abstract: Blood vessel occlusion devices, systems and methods, in particular embodiments of devices for aortic occlusion. The device includes one or more locator portions and an occluder portion. The device is delivered via transcatheter delivery. The locator portion may be radially expanded using a handle and actuator at the proximal end of the delivery catheter. Tactile feedback from the locator portion is used to determine proper location of the occluder portion, for example within the abdominal aorta. The occluder is then radially expanded to occlude the vessel.

Abstract: The disclosed technology relates to endovascular occlusion devices and methods of use. In one embodiment, a method for endovascular occlusion includes delivering an occlusion balloon to a target area of a subject. The delivering includes guiding the occlusion balloon to the target area using non-fluoroscopic detection of the location of a tracking indicator disposed near the occlusion balloon. The method also includes inflating the occlusion balloon at the target area based on at least one pressure associated with the inflation. The at least one pressure is sensed using at least one pressure sensor coupled to the occlusion balloon.

Abstract: A temporary aortic occlusion device is disclosed, having an expandable locator portion and an expandable occlusion portion. The expandable locator portion assists a user in determining whether the distal end of the device has been advanced within a patient's aorta, and the occlusion portion is expanded to occlude the patient's aorta, preferably below the renal arteries.

Abstract: The disclosed technology relates to endovascular occlusion devices and methods of use. In one embodiment, an endovascular occlusion device includes an occlusion balloon, a catheter for delivering the occlusion balloon to a target area of a subject, one or more pressure sensors coupled to the occlusion balloon and configured to sense a pressure associated with inflation of the occlusion balloon at the target area, and a tracking indicator disposed near the occlusion balloon and configured to indicate, to a non-fluoroscopic detection system, a location of the occlusion balloon relative to the target area.

Abstract: The present application provides compositions and methods for imaging traumatic brain injury using PET. The present application discloses using PET ligands targeting infiltrating neutrophils, such as a ligand of FPR, is useful for imaging inflammation. In one aspect, the ligand and imaging agent cFLFLF-PEG-64Cu.

Abstract: The invention relates to methods of reducing formation of atheromas and methods of treating atherosclerotic lesions and/or atherosclerosis by reducing the amount of lumican proteglycan in the intima or an artery or in the lesion. The invention also relates to methods of identifying subjects having or at risk of having atherosclerosis comprising detecting an increased amount of lumican proteoglycan in a subject.

Abstract: A smoking article, such as a cigarette, includes a lighting end and a mouth end. The lighting end is a longitudinally extending segment comprising smokable material that is intended to be lit and burned, and the resulting smoke generated by the burning of that smokable material is intended to be drawn into the mouth of the smoker through the mouth end of smoking article. A mouth end piece is located at the mouth end of the smoking article, and the mouth end piece allows the smoking article to be placed in the mouth of the smoker to be drawn upon. The smoking article further incorporates an aerosol-generation system that is located between the lighting end segment and the mouth end piece. The aerosol-generation system includes (i) a heat generation segment located adjacent to the lighting end segment, and (ii) an aerosol-generation region located between the heat generation segment and the mouth end piece. The aerosol-generation region incorporates an aerosol-forming material (e.g., glycerin and flavors).

Abstract: The invention relates to methods of reducing formation of atheromas and methods of treating atherosclerotic lesions and/or atherosclerosis by reducing the amount of lumican proteglycan in the intima or an artery or in the lesion. The invention also relates to methods of identifying subjects having or at risk of having atherosclerosis comprising detecting an increased amount of lumican proteoglycan in a subject.

Abstract: A fiber optic tester (10) broadly comprises a testing unit (16) to take measurements across two test points (27), a processing unit (18) to locate faults by analyzing the measurements, a switching unit (20) that can connect termination points (13) of a electrical circuit (12) to the test points (27) in a sequence controlled by the processing unit (18), and a fiber unit (22) to test a optical circuit (14). The tester (10) may also include an electrical harness (24) or an optical harness to connect the electrical circuit (12) to the switching unit (20) or the optical circuit (14) to the fiber unit (22). The processing unit (18) is preferably programed with interconnection information of the circuits (12,14) and internal characteristics of the tester (10). Using the interconnection information and the internal characteristics, the processing unit (18) may accurately detect faults within the circuits (12,14).

Abstract: A fiber optic tester (10) broadly comprises a testing unit (16) to take measurements across two test points (27), a processing unit (18) to locate faults by analyzing the measurements, a switching unit (20) that can connect termination points (13) of a electrical circuit (12) to the test points (27) in a sequence controlled by the processing unit (18), and a fiber unit (22) to test a optical circuit (14). The tester (10) may also include an electrical harness (24) or an optical harness to connect the electrical circuit (12) to the switching unit (20) or the optical circuit (14) to the fiber unit (22). The processing unit (18) is preferably programed with interconnection information of the circuits (12, 14) and internal characteristics of the tester (10). Using the interconnection information and the internal characteristics, the processing unit (18) may accurately detect faults within the circuits (12, 14).

Abstract: A fiber optic tester (10) broadly comprises a testing unit (16) to take measurements across two test points (27), a processing unit (18) to locate faults by analyzing the measurements, a switching unit (20) that can connect termination points (13) of a electrical circuit (12) to the test points (27) in a sequence controlled by the processing unit (18), and a fiber unit (22) to test a optical circuit (14). The tester (10) may also include an electrical harness (24) or an optical harness to connect the electrical circuit (12) to the switching unit (20) or the optical circuit (14) to the fiber unit (22). The processing unit (18) is preferably programed with interconnection information of the circuits (12, 14) and internal characteristics of the tester (10). Using the interconnection information and the internal characteristics, the processing unit (18) may accurately detect faults within the circuits (12, 14).

Abstract: A fiber optic tester (10) broadly comprises a testing unit (16) to take measurements across two test points (27), a processing unit (18) to locate faults by analyzing the measurements, a switching unit (20) that can connect termination points (13) of a electrical circuit (12) to the test points (27) in a sequence controlled by the processing unit (18), and a fiber unit (22) to test a optical circuit (14). The tester (10) may also include an electrical harness (24) or an optical harness to connect the electrical circuit (12) to the switching unit (20) or the optical circuit (14) to the fiber unit (22). The processing unit (18) is preferably programed with interconnection information of the circuits (12, 14) and internal characteristics of the tester (10). Using the interconnection information and the internal characteristics, the processing unit (18) may accurately detect faults within the circuits (12, 14).

Abstract: A modular switching and testing system using multiple buses for testing electrical equipment. A switch module selectively switches the test points of the equipment under test to connection with the buses. A routing matrix switches power supplies and instrumentation to the selected buses. Expansion of the system in the field is possible by adding individual circuit boards to provide more termination points or by adding switching modules to provide additional buses.

Abstract: A multiple load-cell weigh scale (10) is disclosed which provides for substantially enhanced accuracy and significantly greater convenience in compensating for load position. The preferred scale (10) includes a platform (12) supported by plurality of digital load cells (14), a central controller (16) for producting a plurality of digital excitation signals representative of a selected excitation voltage for the respective load cells, and an excitation control unit (22) for each load cell for receiving respective excitation signals and for controlling excitation voltage of an associated load cell (20) in accordance therewith.