Patents by Inventor James Ragghianti

James Ragghianti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20060115881
    Abstract: Engineered strains of the oleaginous yeast Yarrowia lipolytica capable of producing greater than 25% eicosapentaenoic acid (EPA, an ?-3 polyunsaturated fatty acid) in the total oil fraction are described. These strains comprise various chimeric genes expressing heterologous desaturases, elongases and acyltransferases and optionally comprise various native desaturase and acyltransferase knockouts to enable synthesis and high accumulation of EPA. Production host cells are claimed, as are methods for producing EPA within said host cells.
    Type: Application
    Filed: November 2, 2005
    Publication date: June 1, 2006
    Inventors: Howard Damude, Peter Gillies, Daniel Macool, Stephen Picataggio, Dana Pollak, James Ragghianti, Zhixiong Xue, Narendra Yadav, Hongxiang Zhang, Quinn Zhu
  • Publication number: 20060110806
    Abstract: An engineered strain of the oleaginous yeast Yarrowia lipolytica capable of producing greater than 5.6% docosahexaenoic acid acid (DHA, an w-3 polyunsaturated fatty acid) in the total oil fraction is described. This strain comprises various chimeric genes expressing heterologous desaturases, elongases and acyltransferases and optionally comprises various native desaturase and acyltransferase knockouts to enable synthesis and high accumulation of DHA. Production host cells are claimed, as are methods for producing DHA within said host cells.
    Type: Application
    Filed: November 1, 2005
    Publication date: May 25, 2006
    Inventors: Howard Damude, Peter Gillies, Daniel Macool, Stephen Picataggio, James Ragghianti, John Seip, Zhixiong Xue, Narendra Yadav, Hongxiang Zhang, Quinn Zhu
  • Publication number: 20060094092
    Abstract: Engineered strains of the oleaginous yeast Yarrowia lipolytica capable of producing greater than 10% arachidonic acid (ARA, an ?-6 polyunsaturated fatty acid) in the total oil fraction are described. These strains comprise various chimeric genes expressing heterologous desaturases, elongases and acyltransferases, and optionally comprise various native desaturase and acyltransferase knockouts to enable synthesis and high accumulation of ARA. Production host cells are claimed, as are methods for producing ARA within said host cells.
    Type: Application
    Filed: November 1, 2005
    Publication date: May 4, 2006
    Inventors: Howard Damude, Peter Gillies, Daniel Macool, Stephen Picataggio, Dana Pollak, James Ragghianti, Zhixiong Xue, Narendra Yadav, Hongxiang Zhang, Quinn Zhu