Patents by Inventor James Raymond Brown
James Raymond Brown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7202071Abstract: The invention provides pth polypeptides and polynucleotides encoding pth polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pth polypeptides to screen for antibacterial compounds.Type: GrantFiled: May 14, 2003Date of Patent: April 10, 2007Assignee: SmithKline Beecham CorporationInventors: Sanjoy Biswas, James Raymond Brown, Christine Debouck, Deborah Dee Jaworski, Elizabeth Jane Lawlor, Jeffrey Mooney, Lisa Kathleen Shilling, Min Wang, Richard Lloyd Warren, Magdalena Zalacain, Yi Yi Zhong, John Peter Throup, Karen Anne Ingraham, Alison Frances Chalker, David John Holmes, Christopher Michael Traini
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Patent number: 6706508Abstract: The invention provides ornithine carbamoyltransferase polypeptides and DNA (RNA) encoding ornithine carbamoyltransferase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ornithine carbamoyltransferase polypeptides to screen for antibacterial compounds.Type: GrantFiled: November 2, 1999Date of Patent: March 16, 2004Assignee: SmithKline Beecham CorporationInventors: James Raymond Brown, Magdalena Zalacain
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Publication number: 20030232373Abstract: The invention provides pth polypeptides and polynucleotides encoding pth polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pth polypeptides to screen for antibacterial compounds.Type: ApplicationFiled: May 14, 2003Publication date: December 18, 2003Applicant: SmithKline Beecham CorporationInventors: Sanjoy Biswas, James Raymond Brown, Christine Debouck, Deborah Dee Jaworski, Elizabeth Jane Lawlor, Jeffrey Mooney, Lisa Kathleen Shilling, Min Wang, Richard Lloyd Warren, Magdalena Zalacain, Yi Yi Zhong, John Peter Throup, Karen Anne Ingraham, Alison Frances Chalker, David John Holmes, Christopher Michael Traini
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Patent number: 6558919Abstract: The invention provides ampS polypeptides and DNA (RNA) encoding ampS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ampS polypeptides to screen for antibacterial compounds.Type: GrantFiled: December 4, 1998Date of Patent: May 6, 2003Assignee: SmithKline Beecham CorporationInventors: Magdalena Zalacain, James Raymond Brown
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Publication number: 20030082614Abstract: The invention provides map polypeptides and polynucleotides encoding map polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing map polypeptides to screen for antibacterial compounds.Type: ApplicationFiled: September 26, 2002Publication date: May 1, 2003Inventors: Sanjoy Biswas, James Raymond Brown, Martin K. R. Burnham, Alison Francis Chalker, David John Holmes, Karen Anne Ingraham, Thomas B. Mathie, Richard Lloyd Warren, Magdalena Zalacain
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Publication number: 20030017532Abstract: The invention provides ndp polypeptides and polynucleotides encoding ndp polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ndp polypeptides to screen for antibacterial compounds.Type: ApplicationFiled: July 27, 2001Publication date: January 23, 2003Inventors: SanJoy Biswas, James Raymond Brown, Martin Karl Russel Burnham, Alison Francis Chalker, David John Holmes, Karen Anne Ingraham, Thomas B. Mathie, Richard Lloyd Warren, Magdalena Zalacain
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Publication number: 20020150963Abstract: The invention provides map polypeptides and polynucleotides encoding map polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing map polypeptides to screen for antibacterial compounds.Type: ApplicationFiled: May 29, 2001Publication date: October 17, 2002Inventors: Sanjoy Biswas, James Raymond Brown, Martin K.R. Burnham, Alison Francis Chalker, David John Holmes, Karen Anne Ingraham, Thomas B. Mathie, Richard Lloyd Warren, Magdalena Zalacain
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Publication number: 20020127596Abstract: The invention provides murF2 polypeptides and polynucleotides encoding murF2 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing murF2 polypeptides to screen for antibacterial compounds.Type: ApplicationFiled: December 13, 2000Publication date: September 12, 2002Inventors: Sanjoy Biswas, James Raymond Brown, Martin K. R. Burnham, Alison Francis Chalker, David John Holmes, Karen Anne Ingraham, Thomas Berthold Mathie, Richard Lloyd Warren, Magdalena Zalacain
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Publication number: 20020123119Abstract: The invention provides histidine kinase polypeptides and DNA (RNA) encoding histidine kinase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing histidine kinase polypeptides to screen for antibacterial compounds.Type: ApplicationFiled: September 10, 2001Publication date: September 5, 2002Inventors: James Raymond Brown, Nicola Gail Wallis, Magdalena Zalacain, Sanjoy Biswas, John Throup
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Publication number: 20020091237Abstract: The invention provides nusB polypeptides and polynucleotides encoding nusB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing nusB polypeptides to screen for antibacterial compounds.Type: ApplicationFiled: May 24, 2001Publication date: July 11, 2002Inventors: Sanjoy Biswas, James Raymond Brown, Martin Karl Russel Burnham, Alison Francis Chalker, David John Holmes, Karen Anne Ingraham, Chi Young So, Richard Lloyd Warren, Magdalena Zalacain
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Patent number: 6399343Abstract: The invention provides infB polypeptides and polynucleotides encoding infB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing in polypeptides to screen for antibacterial compounds.Type: GrantFiled: May 19, 2000Date of Patent: June 4, 2002Assignee: SmithKline Beecham CorporationInventors: Sanjoy Biswas, James Raymond Brown, Martin Karl Russel Burnham, Alison Francis Chalker, Richard Lloyd Warren, Magdalena Zalacain, Chi Young So, Christopher M Traini, David John Holmes, Karen Anne Ingraham, Thomas B Mathie
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Publication number: 20020058799Abstract: The invention provides pth polypeptides and polynucleotides encoding pth polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pth polypeptides to screen for antibacterial compounds.Type: ApplicationFiled: May 2, 2001Publication date: May 16, 2002Inventors: Sanjoy Biswas, James Raymond Brown, Christine Debouck, Deborah Dee Jaworski, Elizabeth Jane Lawlor, Jeffrey Mooney, Lisa Kathleen Shilling, Min Wang, Richard Lloyd Warren, Magdalena Zalacain, Yi Yi Zhong, John Peter Throup, Karen Anne Ingraham, Alison Frances Chalker, David John Holmes, Christopher Michael Traini
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Patent number: 6350600Abstract: The invention provides trmA methyl transferase (trmD) polypeptides and polynucleotides encoding trmD polypeptides and methods for producing such polypeptides by recominant techniques from strepococcus pneumoniae. Also provided are methods for utilizing polypepides to screen for antibacterial compounds.Type: GrantFiled: July 28, 2000Date of Patent: February 26, 2002Assignee: SmithKline Beecham Corp.Inventors: Sanjoy Biswas, James Raymond Brown, Chi Young So, Alison Francis Chalker, David John Holmes, Karen Anne Ingraham, Thomas B Mathie, Richard Lloyd Warren, Magdalena Zalacain
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Patent number: 6348578Abstract: The invention provides apt polypeptides and DNA (RNA) encoding apt polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing apt polypeptides to screen for antibacterial compounds.Type: GrantFiled: October 14, 1999Date of Patent: February 19, 2002Assignees: SmithKline Beecham Corporation, SmithKline Beecham plcInventors: Michael Arthur Lonetto, Richard Oakley Nicholas, James Raymond Brown, Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Robert King Stodola, Magdalena Zalacain
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Publication number: 20020019515Abstract: The invention provides spoIIIE polypeptides and DNA (RNA) encoding spoIIIE polypeptides and methods for producing such polypeptides by recomombinant techniques. Also provided are methods for utilizing spoIIIE polypeptides to screen for antibacterial compounds.Type: ApplicationFiled: February 2, 2001Publication date: February 14, 2002Inventors: Alison Frances Chalker, Maria Magdalena Zalacain Feliu, James Raymond Brown, Alexander Philip Bryant
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Patent number: 6340564Abstract: The invention provides yhxB polypeptides and polynucleotides encoding yhxB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing yhxB polypeptides to screen for antibacterial compounds.Type: GrantFiled: January 26, 1999Date of Patent: January 22, 2002Assignee: SmithKline Beecham CorporationInventors: Karen Anne Ingraham, Chi Yong So, Stephanie Van Horn, Alison Francis Chalker, David John Holmes, Sanjoy Biswas, James Raymond Brown, Martin Karl Russel Burnham, Patrick Vernon Warren, Richard Lloyd Warren, Magdalena Zalacain
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Patent number: 6303771Abstract: The invention provides pth polypeptides and polynucleotides encoding pth polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pth polypeptides to screen for antibacterial compounds.Type: GrantFiled: May 18, 1998Date of Patent: October 16, 2001Assignee: SmithKline Beecham CorporationInventors: Sanjoy Biswas, James Raymond Brown, Christine Debouck, Deborah Dee Jaworski, Elizabeth Jane Lawlor, Jeffrey Mooney, Lisa Kathleen Shilling, Min Wang, Richard Lloyd Warren, Magdalena Zalacain, Yi Yi Zhong, John Peter Throup, Karen Anne Ingraham, Alison Frances Chalker, David John Holmes, Christopher Michael Traini
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Patent number: 6297039Abstract: The invention provides ampS polypeptides and DNA (RNA) encoding ampS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ampS polypeptides to screen for antibacterial compounds.Type: GrantFiled: December 4, 1998Date of Patent: October 2, 2001Assignee: SmithKline Beecham CorporationInventors: Magdalena Zalacain, James Raymond Brown
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Publication number: 20010023064Abstract: The invention provides yfjO polypeptides and polynucleotides encoding yfjO polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing yfjO polypeptides to screen for antibacterial compounds.Type: ApplicationFiled: December 13, 2000Publication date: September 20, 2001Inventors: Sanjoy Biswas, Alexander Bryant, James Raymond Brown, Alison Francis Chalker, David John Holmes, Karen Anne Ingraham, Chi Young So, Stephanie Van Horn, Richard Lloyd Warren, Magdalena Zalacain
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Patent number: 6287836Abstract: The invention provides histidine kinases polypeptides from Streptococcus pneumoniae, fusion polypeptides containing said histidine kinases and truncations of said histidine kinases. The invention also provides compositions comprising histidine kinases from Streptococcus pneumoniae, fusion polypeptides containing said histidine kinases and truncations of said histidine kinases.Type: GrantFiled: October 8, 1997Date of Patent: September 11, 2001Assignee: SmithKline Beecham CorporationInventors: James Raymond Brown, Nicola Gail Wallis, Magdalena Zalacain, Sanjoy Biswas, John Throup