Patents by Inventor James Rebbeor

James Rebbeor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Composition comprising highly-concentrated Alpha1 proteinase inhibitor and method for obtaining thereof
    Patent number: 12144849
    Abstract: Compositions include highly concentrated Alpha-1 Proteinase Inhibitor (A1PI) in a concentration greater than or equal to 100 mg/ml. Pharmaceutical compositions can be prepared from these compositions. The pharmaceutical compositions can be suitable for subcutaneous administration. The highly concentrated A1PI solutions can be obtained by single-pass tangential flow filtration (SPTFF).
    Type: Grant
    Filed: May 12, 2023
    Date of Patent: November 19, 2024
    Assignee: GRIFOLS WORLDWIDE OPERATIONS LIMITED
    Inventors: James Rebbeor, Charles Miller, Anthony Klos, Eric Allgaier, Thomas P. Zimmerman, Kevin Wee, Michelle StPeter, Kelly Glancy
  • METHOD FOR OBTAINING ALPHA-1 PROTEINASE INHIBITOR
    Publication number: 20240262889
    Abstract: A method for obtaining Alpha-1 Proteinase Inhibitor for obtaining highly-concentrated Alpha-1 Proteinase Inhibitor (A1PI) includes preparing a solution of A1PI by concentrating an initial solution of A1PI by tangential flow filtration (TFF) against water. The final concentration of A1PI in the concentrated solution is at least 110 mg/ml. The TFF can be carried out against water for injection (WFD).
    Type: Application
    Filed: February 22, 2021
    Publication date: August 8, 2024
    Inventors: James REBBEOR, Jeffrey A. YUZIUK, George GRADY, Dennis McBRIDE
  • COMPOSITION COMPRISING HIGHLY-CONCENTRATED ALPHA1 PROTEINASE INHIBITOR AND METHOD FOR OBTAINING THEREOF
    Publication number: 20230277636
    Abstract: Compositions include highly concentrated Alpha-1 Proteinase Inhibitor (A1PI) in a concentration greater than or equal to 100 mg/ml. Pharmaceutical compositions can be prepared from these compositions. The pharmaceutical compositions can be suitable for subcutaneous administration. The highly concentrated A1PI solutions can be obtained by single-pass tangential flow filtration (SPTFF).
    Type: Application
    Filed: May 12, 2023
    Publication date: September 7, 2023
    Inventors: James REBBEOR, Charles MILLER, Anthony KLOS, Eric ALLGAIER, Thomas P. ZIMMERMAN, Kevin WEE, Michelle StPETER, Kelly GLANCY
  • Composition comprising highly-concentrated ?1 proteinase inhibitor and method for obtaining thereof
    Patent number: 11701412
    Abstract: Compositions include highly-concentrated Alpha-1 Proteinase Inhibitor (A1PI) in a concentration greater than or equal to 100 mg/ml. Pharmaceutical compositions can be prepared from these compositions. The pharmaceutical compositions can be suitable for subcutaneous administration. The highly-concentrated A1PI solutions can be obtained by single-pass tangential flow filtration (SPTFF).
    Type: Grant
    Filed: September 22, 2021
    Date of Patent: July 18, 2023
    Assignee: GRIFOLS WORLDWIDE OPERATIONS LIMITED
    Inventors: James Rebbeor, Charles Miller, Anthony Klos, Eric Allgaier, Thomas P. Zimmerman, Kevin Wee, Michelle StPeter, Kelly Glancy
  • Composition comprising highly-concentrated ALPHA1 proteinase inhibitor and method for obtaining thereof
    Patent number: 11253578
    Abstract: Compositions include highly-concentrated Alpha-1 Proteinase Inhibitor (A1PI) in a concentration greater than or equal to 100 mg/ml. Pharmaceutical compositions can be prepared from these compositions. The pharmaceutical compositions can be suitable for subcutaneous administration. The highly-concentrated A1PI solutions can be obtained by single-pass tangential flow filtration (SPTFF).
    Type: Grant
    Filed: August 1, 2019
    Date of Patent: February 22, 2022
    Assignee: GRIFOLS WORLDWIDE OPERATIONS LIMITED
    Inventors: James Rebbeor, Charles Miller, Anthony Klos, Eric Allgaier, Thomas P. Zimmerman, Kevin Wee, Michelle StPeter, Kelly Glancy
  • Compositions, methods and kits for preparing plasminogen and plasmin prepared therefrom
    Patent number: 9206410
    Abstract: Compositions and methods for preparing plasminogen, in particular recombinant plasminogen, and compositions and methods of utilizing same for preparing plasmin are provided.
    Type: Grant
    Filed: March 2, 2010
    Date of Patent: December 8, 2015
    Assignee: GRIFOLS THERAPEUTICS INC.
    Inventors: Edward Koepf, Myles Lindsay, Rebecca Silverstein, Jennifer Hunt, James Rebbeor, Thomas Zimmerman, Charles Miller, Anthony Caronna, Kenya Stokes
  • COMPOSITIONS, METHODS, AND KITS FOR PREPARING PLASMINOGEN; AND PLASMIN PREPARED THEREFROM
    Publication number: 20150329845
    Abstract: Compositions and methods for preparing plasminogen, in particular recombinant plasminogen, and compositions and methods of utilizing same for preparing plasmin are provided.
    Type: Application
    Filed: August 5, 2015
    Publication date: November 19, 2015
    Inventors: Edward Koepf, Myles Lindsay, Rebecca Silverstein, Jennifer Hunt, James Rebbeor, Thomas Zimmerman, Charles Miller, Anthony Caronna, Kenya Stokes
  • COMPOSITIONS, METHODS AND KITS FOR PREPARING PLASMINOGEN AND PLASMIN PREPARED THEREFROM
    Publication number: 20120009650
    Abstract: Compositions and methods for preparing plasminogen, in particular recombinant plasminogen, and compositions and methods of utilizing same for preparing plasmin are provided.
    Type: Application
    Filed: March 2, 2010
    Publication date: January 12, 2012
    Applicant: Talecris Biotherapeutics, Inc.
    Inventors: Edward Koepf, Myies Lindsay, Rebecca Silverstein, Jennifer Hunt, James Rebbeor, Thomas Zimmerman, Charles Miller, Anthony Caronna, Kenya Stokes
  • Sanitization of chromatographic media
    Publication number: 20050006307
    Abstract: A method of sanitizing chromatographic media is provided. The method includes contacting the media with an acidic chaotropic agent, at low temperature and low pH. The method provides pathogen removal and/or inactivation, including viral inactivation in particular embodiments.
    Type: Application
    Filed: July 8, 2003
    Publication date: January 13, 2005
    Inventors: Nathan Jones, Marina Korneyeva, James Rebbeor, Richard Rosenthal, Christopher Stenland