Abstract: Aspects of the present disclosure relate to a method of regenerating a hydrophobic interaction chromatography column to which a load mass has been applied, the method comprising passing one or more column volumes of an alkaline solution through hydrophobic interaction media within the column, wherein the alkaline solution exhibits a pH of between about 10 and about 14, and a conductivity of between 0.5 mS/cm and about 10 mS/cm, wherein material bound to the hydrophobic interaction media is removed. In some cases, the alkaline solution may include sodium hydroxide at a concentration of between, e.g., about 0.1 mM and 10 mM.

Abstract: A method for error management is provided. The method comprises receiving a message call request regarding an error event generated by a software application. The message call request comprises a message ID associated with an error type. In response to the call request a message cache is searched for the message ID. If the ID is in the cache, an error message associated with the ID is returned. The error message provides a description of the error and suggested remedial action. If the message ID is not in the cache, the error message is fetched from a message repository that contains error messages corresponding to respective message IDs. The fetched error message is loaded into the cache and returned. Message call request data is stored in a metrics repository. The message call request data comprises frequency metrics that describe how often the message ID is received.

Abstract: The disclosed exemplary embodiments include computer-implemented systems, apparatuses, and processes that, among other things, automatically populate, in real-time, portions of digital interfaces based on dynamically generated contextual data. For example, a network-connected apparatus may receive, from a device, a portion of an identifier of a first counterparty to an exchange of data. The apparatus may perform operations determine a second counterparty to the data exchange based on at least one of a current geographic position of the first device, a first element of profile data associated with the first device, or the received portion of the first counterparty identifier, and may transmit an identifier of the second counterparty to the device. The device may execute an application program that presents the second counterparty identifier within a corresponding portion of an interface associated with the data exchange.

Abstract: A preemptive optimization of a power distribution event associated with providing an electrical power from a battery onboard a vehicle to a charging station offboard the vehicle. The preemptive optimization may include preemptively charging the battery in advance of the power distribution event and/or preemptively configuring the vehicle and the battery, such as with establishment of standby session, to provide electrical power from the battery to the charging station without providing the electrical power to the charging station until the charging station thereafter experiences an outage, interrupt, etc.

Abstract: A preemptive optimization of a power distribution event associated with providing an electrical power from a battery onboard a vehicle to a charging station offboard the vehicle. The preemptive optimization may include preemptively charging the battery in advance of the power distribution event and/or preemptively configuring the vehicle and the battery, such as with establishment of standby session, to provide electrical power from the battery to the charging station without providing the electrical power to the charging station until the charging station thereafter experiences an outage, interrupt, etc.

Abstract: Embodiments of the present disclosure are directed to methods for preparing a target polypeptide from a mixture including the target polypeptide. The method may include contacting the mixture to a hydrophobic interaction chromatography (HIC) apparatus including multiple chromatographic zones. The method may further include passing the target polypeptide through the outlets of at least a first zone and a second zone of the HIC apparatus. A residence time for the mixture including the target polypeptide in a first zone may be approximately the same as a residence time of one or more mobile phases in the second zone.

Abstract: A knowledge hub system and method is provided, based on personal knowledge and a plurality of documents, texts, or images generated by an individual or group saved in a user profile. A visual map is formed based on documents returned from keyword searches to connected databases, where visualizations and proximities are determined between known knowledge (such as search terms, a known article or articles, known content, and the like), and unknown knowledge, also known as latent knowledge (search results), based on a computerized analysis of similarities between search terms, documents, and key features of content in the knowledge hub. The resultant visualizations and maps may be used for various purposes including internet searching, organizing documents, project collaboration, thematic stratification of text- or image-based data, concept mapping, knowledge commercialization, and the like.

Abstract: The disclosed embodiments include computer-implemented systems, apparatuses, and processes that, among other things, automatically generate and populate digital interfaces based on adaptively processed image data captured by a network-connected device operating within a computing environment. For example, an apparatus may receive, from a device, a first signal that includes image data identifying a document associated with a data exchange capable of initiation by the device. The apparatus may detect, within a first portion of the image data, a presence of first textual content associated with a first parameter of the data exchange, extract a first value characterizing the first parameter from the first textual content, and generate and transmit a second signal that includes the first value to the device. The second signal includes information that instructs the device to display the first value within a portion of an interface corresponding to the first parameter.

Abstract: A method for error management is provided. The method comprises receiving a message call request regarding an error event generated by a software application. The message call request comprises a message ID associated with an error type. In response to the call request a message cache is searched for the message ID. If the ID is in the cache, an error message associated with the ID is returned. The error message provides a description of the error and suggested remedial action. If the message ID is not in the cache, the error message is fetched from a message repository that contains error messages corresponding to respective message IDs. The fetched error message is loaded into the cache and returned. Message call request data is stored in a metrics repository. The message call request data comprises frequency metrics that describe how often the message ID is received.

Abstract: Embodiments of the present disclosure are directed to methods for preparing a target polypeptide from a mixture including the target polypeptide. The method may include contacting the mixture to a hydrophobic interaction chromatography (HIC) apparatus including multiple chromatographic zones. The method may further include passing the target polypeptide through the outlets of at least a first zone and a second zone of the HIC apparatus. A residence time for the mixture including the target polypeptide in a first zone may be approximately the same as a residence time of one or more mobile phases in the second zone.

Abstract: The present invention pertains to methods for manufacturing high titer antibody products. In particular, the invention pertains, in part, to improved serum-free animal cell culture medium, which can used for the production of a protein of interest. Additionally, the present invention further pertains to chromatographic procedures employed to successfully isolate the antibody product subject of the present disclosure.

Abstract: The present invention pertains to methods for manufacturing high titer antibody products. In particular, the invention pertains, in part, to improved serum-free animal cell culture medium, which can used for the production of a protein of interest. Additionally, the present invention further pertains to chromatographic procedures employed to successfully isolate the antibody product subject of the present disclosure.

Abstract: A method for error management is provided. The method comprises receiving a message call request regarding an error event generated by a software application. The message call request comprises a message ID associated with an error type. In response to the call request a message cache is searched for the message ID. If the ID is in the cache, an error message associated with the ID is returned. The error message provides a description of the error and suggested remedial action. If the message ID is not in the cache, the error message is fetched from a message repository that contains error messages corresponding to respective message IDs. The fetched error message is loaded into the cache and returned. Message call request data is stored in a metrics repository. The message call request data comprises frequency metrics that describe how often the message ID is received.

Abstract: The present invention pertains to methods for manufacturing high titer antibody products. In particular, the invention pertains, in part, to improved serum-free animal cell culture medium, which can used for the production of a protein of interest. Additionally, the present invention further pertains to chromatographic procedures employed to successfully isolate the antibody product subject of the present disclosure.

Abstract: The present invention pertains to methods for manufacturing high titer antibody products. In particular, the invention pertains, in part, to improved serum-free animal cell culture medium, which can used for the production of a protein of interest. Additionally, the present invention further pertains to chromatographic procedures employed to successfully isolate the antibody product subject of the present disclosure.

Abstract: The present invention pertains to methods for manufacturing high titer antibody products. In particular, the invention pertains, in part, to improved serum-free animal cell culture medium, which can used for the production of a protein of interest. Additionally, the present invention further pertains to chromatographic procedures employed to successfully isolate the antibody product subject of the present disclosure.

Abstract: The present invention pertains to methods for manufacturing high titer antibody products. In particular, the invention pertains, in part, to improved serum-free animal cell culture medium, which can used for the production of a protein of interest. Additionally, the present invention further pertains to chromatographic procedures employed to successfully isolate the antibody product subject of the present disclosure.

Abstract: The present disclosure generally relates to synthesizing one or more properties for optimizing one or more operations in a well. Embodiments include receiving measurements or qualitative indicators of one or more parameters in association with performing operations in the well. Embodiments include providing, based on the measurements, one or more inputs to a machine learning algorithm (MLA) that has been trained using historical or training well data. Embodiments include determining, based on one or more outputs from the MLA, one or more synthesized properties relating to the well, wherein the one or more synthesized properties comprise a synthesized pore-pressure at, near, or ahead of a bit position. Embodiments include determining, based on the one or more synthesized properties, one or more optimized parameters relating to at least one of: drilling the well; steering the well; or stimulating a reservoir.

Abstract: A computerized data transfer system allows data transfers to be initiated over a network between senders and recipients. Individual senders initiate data transfers over the network by selecting a recipient from a list at a sender device. The system includes a data store of sender specific recipients, a data transfer history data store of past transfers; and a master participant data store storing profiles of recipients for which transfers can be initiated. The system includes a computing device that for selected senders, retrieves entries of the data store of sender specific recipients, master participant data store and data transfer history data store; generates a predicted transfer profile for each recipient for the sender, based on past data transfers and the master participant data store to identify deviations therefrom; and updates the data store of sender specific recipients for the selected sender to update entries for recipients associated with identified deviations.

Abstract: A method for error management is provided. The method comprises receiving a message call request regarding an error event generated by a software application. The message call request comprises a message ID associated with an error type. In response to the call request a message cache is searched for the message ID. If the ID is in the cache, an error message associated with the ID is returned. The error message provides a description of the error and suggested remedial action. If the message ID is not in the cache, the error message is fetched from a message repository that contains error messages corresponding to respective message IDs. The fetched error message is loaded into the cache and returned. Message call request data is stored in a metrics repository. The message call request data comprises frequency metrics that describe how often the message ID is received.