Patents by Inventor James Reilly

James Reilly has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12246305
    Abstract: Aspects of the present disclosure relate to a method of regenerating a hydrophobic interaction chromatography column to which a load mass has been applied, the method comprising passing one or more column volumes of an alkaline solution through hydrophobic interaction media within the column, wherein the alkaline solution exhibits a pH of between about 10 and about 14, and a conductivity of between 0.5 mS/cm and about 10 mS/cm, wherein material bound to the hydrophobic interaction media is removed. In some cases, the alkaline solution may include sodium hydroxide at a concentration of between, e.g., about 0.1 mM and 10 mM.
    Type: Grant
    Filed: September 23, 2020
    Date of Patent: March 11, 2025
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Robert Stairs, James Reilly, John Mattila, Samantha Wadsworth
  • Patent number: 12235716
    Abstract: A method for error management is provided. The method comprises receiving a message call request regarding an error event generated by a software application. The message call request comprises a message ID associated with an error type. In response to the call request a message cache is searched for the message ID. If the ID is in the cache, an error message associated with the ID is returned. The error message provides a description of the error and suggested remedial action. If the message ID is not in the cache, the error message is fetched from a message repository that contains error messages corresponding to respective message IDs. The fetched error message is loaded into the cache and returned. Message call request data is stored in a metrics repository. The message call request data comprises frequency metrics that describe how often the message ID is received.
    Type: Grant
    Filed: October 27, 2023
    Date of Patent: February 25, 2025
    Assignee: ADP, Inc.
    Inventors: Anand Muralidharan, Kingbert Thomas, Balasubramanian Paulraj, Venkateshkumar Muthu, Vidyavathi Vennapusa, Gareth Harries, Neil Hopkins, Subramaniam Ramalingasamy, Raja Ambigapathy Karuppasamy, James Reilly
  • Patent number: 12061652
    Abstract: The disclosed exemplary embodiments include computer-implemented systems, apparatuses, and processes that, among other things, automatically populate, in real-time, portions of digital interfaces based on dynamically generated contextual data. For example, a network-connected apparatus may receive, from a device, a portion of an identifier of a first counterparty to an exchange of data. The apparatus may perform operations determine a second counterparty to the data exchange based on at least one of a current geographic position of the first device, a first element of profile data associated with the first device, or the received portion of the first counterparty identifier, and may transmit an identifier of the second counterparty to the device. The device may execute an application program that presents the second counterparty identifier within a corresponding portion of an interface associated with the data exchange.
    Type: Grant
    Filed: July 22, 2021
    Date of Patent: August 13, 2024
    Assignee: The Toronto-Dominion Bank
    Inventors: Robert Kyle Miller, Sonja Torbica, Helene Nicole Esposito, Harrison Michael James Reilly, Matta Wakim, Kyryll Odobetskiy, Dexter Lamont Fichuk, Adam Douglas McPhee, Omas Abdullah
  • Patent number: 12046906
    Abstract: A preemptive optimization of a power distribution event associated with providing an electrical power from a battery onboard a vehicle to a charging station offboard the vehicle. The preemptive optimization may include preemptively charging the battery in advance of the power distribution event and/or preemptively configuring the vehicle and the battery, such as with establishment of standby session, to provide electrical power from the battery to the charging station without providing the electrical power to the charging station until the charging station thereafter experiences an outage, interrupt, etc.
    Type: Grant
    Filed: January 6, 2023
    Date of Patent: July 23, 2024
    Assignee: GM Global Technology Operations LLC
    Inventors: Patricia M. Laskowsky, Aniket P. Kothari, Bridget A. Beaton, James Reilly, James C. Gibbs, Christopher Rowe
  • Publication number: 20240235204
    Abstract: A preemptive optimization of a power distribution event associated with providing an electrical power from a battery onboard a vehicle to a charging station offboard the vehicle. The preemptive optimization may include preemptively charging the battery in advance of the power distribution event and/or preemptively configuring the vehicle and the battery, such as with establishment of standby session, to provide electrical power from the battery to the charging station without providing the electrical power to the charging station until the charging station thereafter experiences an outage, interrupt, etc.
    Type: Application
    Filed: January 6, 2023
    Publication date: July 11, 2024
    Applicant: GM GLOBAL TECHNOLOGY OPERATIONS LLC
    Inventors: Patricia M. Laskowsky, Aniket P. Kothari, Bridget A. Beaton, James Reilly, James C. Gibbs, Christopher Rowe
  • Publication number: 20240209021
    Abstract: Embodiments of the present disclosure are directed to methods for preparing a target polypeptide from a mixture including the target polypeptide. The method may include contacting the mixture to a hydrophobic interaction chromatography (HIC) apparatus including multiple chromatographic zones. The method may further include passing the target polypeptide through the outlets of at least a first zone and a second zone of the HIC apparatus. A residence time for the mixture including the target polypeptide in a first zone may be approximately the same as a residence time of one or more mobile phases in the second zone.
    Type: Application
    Filed: December 15, 2023
    Publication date: June 27, 2024
    Applicant: Regeneron Pharmaceuticals, Inc.
    Inventors: Isabelle LIVIGNI, Stefanie MCDERMOTT, James REILLY, John MATTILA
  • Publication number: 20240193192
    Abstract: A knowledge hub system and method is provided, based on personal knowledge and a plurality of documents, texts, or images generated by an individual or group saved in a user profile. A visual map is formed based on documents returned from keyword searches to connected databases, where visualizations and proximities are determined between known knowledge (such as search terms, a known article or articles, known content, and the like), and unknown knowledge, also known as latent knowledge (search results), based on a computerized analysis of similarities between search terms, documents, and key features of content in the knowledge hub. The resultant visualizations and maps may be used for various purposes including internet searching, organizing documents, project collaboration, thematic stratification of text- or image-based data, concept mapping, knowledge commercialization, and the like.
    Type: Application
    Filed: December 7, 2023
    Publication date: June 13, 2024
    Inventors: James Reilly, IV, Chris Burke, John Cave
  • Patent number: 12008315
    Abstract: The disclosed embodiments include computer-implemented systems, apparatuses, and processes that, among other things, automatically generate and populate digital interfaces based on adaptively processed image data captured by a network-connected device operating within a computing environment. For example, an apparatus may receive, from a device, a first signal that includes image data identifying a document associated with a data exchange capable of initiation by the device. The apparatus may detect, within a first portion of the image data, a presence of first textual content associated with a first parameter of the data exchange, extract a first value characterizing the first parameter from the first textual content, and generate and transmit a second signal that includes the first value to the device. The second signal includes information that instructs the device to display the first value within a portion of an interface corresponding to the first parameter.
    Type: Grant
    Filed: January 7, 2021
    Date of Patent: June 11, 2024
    Assignee: The Toronto-Dominion Bank
    Inventors: Robert Kyle Miller, Sonja Torbica, Helene Nicole Esposito, Harrison Michael James Reilly, Matta Wakim, Kyryll Odobetskiy, Dexter Lamont Fichuk, Adam Douglas McPhee, Omas Abdullah, Patrick Jian Hong Hum
  • Publication number: 20240061737
    Abstract: A method for error management is provided. The method comprises receiving a message call request regarding an error event generated by a software application. The message call request comprises a message ID associated with an error type. In response to the call request a message cache is searched for the message ID. If the ID is in the cache, an error message associated with the ID is returned. The error message provides a description of the error and suggested remedial action. If the message ID is not in the cache, the error message is fetched from a message repository that contains error messages corresponding to respective message IDs. The fetched error message is loaded into the cache and returned. Message call request data is stored in a metrics repository. The message call request data comprises frequency metrics that describe how often the message ID is received.
    Type: Application
    Filed: October 27, 2023
    Publication date: February 22, 2024
    Applicant: ADP, Inc.
    Inventors: Anand Muralidharan, Kingbert Thomas, Balasubramanian Paulraj, Venkateshkumar Muthu, Vidyavathi Vennapusa, Gareth Harries, Neil Hopkins, Subramaniam Ramalingasamy, Raja Ambigapathy Karuppasamy, James Reilly
  • Patent number: 11884698
    Abstract: Embodiments of the present disclosure are directed to methods for preparing a target polypeptide from a mixture including the target polypeptide. The method may include contacting the mixture to a hydrophobic interaction chromatography (HIC) apparatus including multiple chromatographic zones. The method may further include passing the target polypeptide through the outlets of at least a first zone and a second zone of the HIC apparatus. A residence time for the mixture including the target polypeptide in a first zone may be approximately the same as a residence time of one or more mobile phases in the second zone.
    Type: Grant
    Filed: July 1, 2019
    Date of Patent: January 30, 2024
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Isabelle Livigni, Stefanie McDermott, James Reilly, John Mattila
  • Publication number: 20240010737
    Abstract: The present invention pertains to methods for manufacturing high titer antibody products. In particular, the invention pertains, in part, to improved serum-free animal cell culture medium, which can used for the production of a protein of interest. Additionally, the present invention further pertains to chromatographic procedures employed to successfully isolate the antibody product subject of the present disclosure.
    Type: Application
    Filed: February 28, 2023
    Publication date: January 11, 2024
    Inventors: John Mattila, Xiaolin Tang, Hanne Bak, Shawn M. Lawrence, Amy S. Johnson, Meghan Casey, Michelle LaFond, Andrew Tustian, Philip Mellors, John Hourihan, John Crowley, Laura Callinan, Shadia Abike Oshodi, Ashley Witmer, Daniel Corbett, James Reilly, Ankit Vartak, Mark Chiboroski, Alessandra Starling, Robert Stairs, Hai-Yuan Goh, Liam Nicholl, Aishling Conlon
  • Publication number: 20230348532
    Abstract: The present invention pertains to methods for manufacturing high titer antibody products. In particular, the invention pertains, in part, to improved serum-free animal cell culture medium, which can used for the production of a protein of interest. Additionally, the present invention further pertains to chromatographic procedures employed to successfully isolate the antibody product subject of the present disclosure.
    Type: Application
    Filed: February 28, 2023
    Publication date: November 2, 2023
    Inventors: John Mattila, Xiaolin Tang, Hanne Bak, Shawn M. Lawrence, Amy S. Johnson, Meghan Casey, Michelle LaFond, Andrew Tustian, Philip Mellors, John Hourihan, John Crowley, Laura Callinan, Shadia Abike Oshodi, Ashley Witmer, Daniel Corbett, James Reilly, Ankit Vartak, Mark Chiboroski, Alessandra Starling, Robert Stairs, Hai-Yuan Goh, Liam Nicholl, Aishling Conlon
  • Patent number: 11803438
    Abstract: A method for error management is provided. The method comprises receiving a message call request regarding an error event generated by a software application. The message call request comprises a message ID associated with an error type. In response to the call request a message cache is searched for the message ID. If the ID is in the cache, an error message associated with the ID is returned. The error message provides a description of the error and suggested remedial action. If the message ID is not in the cache, the error message is fetched from a message repository that contains error messages corresponding to respective message IDs. The fetched error message is loaded into the cache and returned. Message call request data is stored in a metrics repository. The message call request data comprises frequency metrics that describe how often the message ID is received.
    Type: Grant
    Filed: July 13, 2021
    Date of Patent: October 31, 2023
    Assignee: ADP, INC.
    Inventors: Anand Muralidharan, Kingbert Thomas, Balasubramanian Paulraj, Venkateshkumar Muthu, Vidyavathi Vennapusa, Gareth Harries, Neil Hopkins, Subramaniam Ramalingasamy, Raja Ambigapathy Karuppasamy, James Reilly
  • Publication number: 20230332201
    Abstract: The present invention pertains to methods for manufacturing high titer antibody products. In particular, the invention pertains, in part, to improved serum-free animal cell culture medium, which can used for the production of a protein of interest. Additionally, the present invention further pertains to chromatographic procedures employed to successfully isolate the antibody product subject of the present disclosure.
    Type: Application
    Filed: February 28, 2023
    Publication date: October 19, 2023
    Inventors: John Mattila, Xiaolin Tang, Hanne Bak, Shawn M. Lawrence, Amy S. Johnson, Meghan Casey, Michelle LaFond, Andrew Tustian, Philip Mellors, John Hourihan, John Crowley, Laura Callinan, Shadia Abike Oshodi, Ashley Witmer, Daniel Corbett, James Reilly, Ankit Vartak, Mark Chiboroski, Alessandra Starling, Robert Stairs, Hai-Yuan Goh, Liam Nicholl, Aishling Conlon
  • Publication number: 20230331776
    Abstract: The present invention pertains to methods for manufacturing high titer antibody products. In particular, the invention pertains, in part, to improved serum-free animal cell culture medium, which can used for the production of a protein of interest. Additionally, the present invention further pertains to chromatographic procedures employed to successfully isolate the antibody product subject of the present disclosure.
    Type: Application
    Filed: February 28, 2023
    Publication date: October 19, 2023
    Inventors: John Mattila, Xiaolin Tang, Hanne Bak, Shawn M. Lawrence, Amy S. Johnson, Meghan Casey, Michelle LaFond, Andrew Tustian, Philip Mellors, John Hourihan, John Crowley, Laura Callinan, Shadia Abike Oshodi, Ashley Witmer, Daniel Corbett, James Reilly, Ankit Vartak, Mark Chiboroski, Alessandra Starling, Robert Stairs, Hai-Yuan Goh, Liam Nicholl, Aishling Conlon
  • Publication number: 20230332084
    Abstract: The present invention pertains to methods for manufacturing high titer antibody products. In particular, the invention pertains, in part, to improved serum-free animal cell culture medium, which can used for the production of a protein of interest. Additionally, the present invention further pertains to chromatographic procedures employed to successfully isolate the antibody product subject of the present disclosure.
    Type: Application
    Filed: February 28, 2023
    Publication date: October 19, 2023
    Inventors: John Mattila, Xiaolin Tang, Hanne Bak, Shawn M. Lawrence, Amy Johnson, Meghan Casey, Michelle LaFond, Andrew Tustian, Philip Mellors, John Hourihan, John Crowley, Laura Callinan, Shadia Abike Oshodi, Ashley Witmer, Daniel Corbett, James Reilly, Ankit Vartak, Mark Chiboroski, Alessandra Starling, Robert Stairs, Hai-Yuan Goh, Liam Nicholl, Aishling Conlon
  • Publication number: 20230287043
    Abstract: The present invention pertains to methods for manufacturing high titer antibody products. In particular, the invention pertains, in part, to improved serum-free animal cell culture medium, which can used for the production of a protein of interest. Additionally, the present invention further pertains to chromatographic procedures employed to successfully isolate the antibody product subject of the present disclosure.
    Type: Application
    Filed: February 28, 2023
    Publication date: September 14, 2023
    Inventors: John Mattila, Xiaolin Tang, Hanne Bak, Shawn M. Lawrence, Amy S. Johnson, Meghan Casey, Michelle LaFond, Andrew Tustian, Philip Mellors, John Hourihan, John Crowley, Laura Callinan, Shadia Abike Oshodi, Ashley Witmer, Daniel Corbett, James Reilly, Ankit Vartak, Mark Chiboroski, Alessandra Starling, Robert Stairs, Hai-Yuan Goh, Liam Nicholl, Aishling Conlon
  • Publication number: 20230258077
    Abstract: The present disclosure generally relates to synthesizing one or more properties for optimizing one or more operations in a well. Embodiments include receiving measurements or qualitative indicators of one or more parameters in association with performing operations in the well. Embodiments include providing, based on the measurements, one or more inputs to a machine learning algorithm (MLA) that has been trained using historical or training well data. Embodiments include determining, based on one or more outputs from the MLA, one or more synthesized properties relating to the well, wherein the one or more synthesized properties comprise a synthesized pore-pressure at, near, or ahead of a bit position. Embodiments include determining, based on the one or more synthesized properties, one or more optimized parameters relating to at least one of: drilling the well; steering the well; or stimulating a reservoir.
    Type: Application
    Filed: February 14, 2022
    Publication date: August 17, 2023
    Applicants: Hess Corporation
    Inventors: Barry F. ZHANG, Orlando DE JESUS, Muhlis UNALDI, Matthew James REILLY
  • Publication number: 20230047003
    Abstract: A computerized data transfer system allows data transfers to be initiated over a network between senders and recipients. Individual senders initiate data transfers over the network by selecting a recipient from a list at a sender device. The system includes a data store of sender specific recipients, a data transfer history data store of past transfers; and a master participant data store storing profiles of recipients for which transfers can be initiated. The system includes a computing device that for selected senders, retrieves entries of the data store of sender specific recipients, master participant data store and data transfer history data store; generates a predicted transfer profile for each recipient for the sender, based on past data transfers and the master participant data store to identify deviations therefrom; and updates the data store of sender specific recipients for the selected sender to update entries for recipients associated with identified deviations.
    Type: Application
    Filed: November 1, 2022
    Publication date: February 16, 2023
    Applicant: The Toronto-Dominion Bank
    Inventors: Robert Kyle MILLER, Sonja TORBICA, Helene Nicole ESPOSITO, Harrison Michael James REILLY, Matta WAKIM, Kyryll ODOBETSKIY, Dexter Lamont FICHUK, Adam Douglas McPHEE, Omas ABDULLAH
  • Publication number: 20230014879
    Abstract: A method for error management is provided. The method comprises receiving a message call request regarding an error event generated by a software application. The message call request comprises a message ID associated with an error type. In response to the call request a message cache is searched for the message ID. If the ID is in the cache, an error message associated with the ID is returned. The error message provides a description of the error and suggested remedial action. If the message ID is not in the cache, the error message is fetched from a message repository that contains error messages corresponding to respective message IDs. The fetched error message is loaded into the cache and returned. Message call request data is stored in a metrics repository. The message call request data comprises frequency metrics that describe how often the message ID is received.
    Type: Application
    Filed: July 13, 2021
    Publication date: January 19, 2023
    Inventors: Anand Muralidharan, Kingbert Thomas, Balasubramanian Paulraj, Venkateshkumar Muthu, Vidyavathi Vennapusa, Gareth Harries, Neil Hopkins, Subramaniam Ramalingasamy, Raja Ambigapathy Karuppasamy, James Reilly