Patents by Inventor James Richard BERENSON

James Richard BERENSON has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GAMMA SECRETASE MODULATORS FOR THE TREATMENT OF IMMUNE SYSTEM DYSFUNCTION
    Publication number: 20230405124
    Abstract: The present invention provides methods of treating an immune system dysfunction or conditions associated with soluble BCMA using gamma secretase modulators or inhibitors in order to both restore immune function and improve the efficacy of therapies directed against BCMA present on the pathogenic B cell.
    Type: Application
    Filed: September 1, 2023
    Publication date: December 21, 2023
    Inventor: James Richard BERENSON
  • Methods for monitoring immune status of a subject
    Patent number: 11698369
    Abstract: The invention generally provides improved compositions and methods for monitoring immune status of a subject. In particular, the invention provides methods for detecting BCMA in subjects to reliably monitor immune status of the subject.
    Type: Grant
    Filed: January 12, 2017
    Date of Patent: July 11, 2023
    Assignee: ONCOTRACKER, INC.
    Inventor: James Richard Berenson
  • Diagnostic, prognostic, and monitoring methods for solid tumor cancers
    Patent number: 11635435
    Abstract: The compositions and methods of the invention relate generally to detection of biomarkers for the diagnosis, prognosis, and monitoring of solid tumor cancers. In particular, the invention relates to compositions and methods for detection of B-cell maturation antigen (BCMA) for the diagnosis, prognosis, and monitoring of solid tumor type of cancers.
    Type: Grant
    Filed: June 13, 2018
    Date of Patent: April 25, 2023
    Assignee: ONCOTRACKER, INC.
    Inventor: James Richard Berenson
  • METHOD OF ENHANCING IMMUNE-BASED THERAPY
    Publication number: 20220000872
    Abstract: The present invention provides methods of treating and/or inhibiting cancer by administering a JAK1/2 inhibitor (e.g., ruxolitinib). The JAK1/2 inhibitor decreases expression of (or inhibits increased expression of) the checkpoint proteins PD-1, PD-L1, PD-L2, or B7 H3, and/or enhances T-cell killing of tumor cells, and/or enhances the anti-tumor effects of checkpoint inhibitors. The disclosed methods improve the efficacy of immune-based therapies used in treatment of cancer.
    Type: Application
    Filed: October 31, 2019
    Publication date: January 6, 2022
    Inventors: James Richard BERENSON, Haiming CHEN
  • IMPROVED METHODS FOR MONITORING IMMUNE STATUS OF A SUBJECT
    Publication number: 20200326339
    Abstract: The invention generally provides improved compositions and methods for monitoring immune status of a subject. In particular, the invention provides methods for detecting BAFF polypeptide or a fragment thereof in subjects to reliably monitor immune status of the subject.
    Type: Application
    Filed: May 16, 2017
    Publication date: October 15, 2020
    Inventor: James Richard BERENSON
  • DIAGNOSTIC, PROGNOSTIC, AND MONITORING METHODS FOR SOLID TUMOR CANCERS
    Publication number: 20200264184
    Abstract: The compositions and methods of the invention relate generally to detection of biomarkers for the diagnosis, prognosis, and monitoring of solid tumor cancers. In particular, the invention relates to compositions and methods for detection of B-cell maturation antigen (BCMA) for the diagnosis, prognosis, and monitoring of solid tumor type of cancers.
    Type: Application
    Filed: June 13, 2018
    Publication date: August 20, 2020
    Inventor: James Richard BERENSON
  • IMPROVED METHODS FOR MONITORING IMMUNE STATUS OF A SUBJECT
    Publication number: 20190049437
    Abstract: The invention generally provides improved compositions and methods for monitoring immune status of a subject. In particular, the invention provides methods for detecting BCMA in subjects to reliably monitor immune status of the subject.
    Type: Application
    Filed: January 12, 2017
    Publication date: February 14, 2019
    Inventor: James Richard BERENSON
  • GAMMA SECRETASE MODULATORS FOR THE TREATMENT OF IMMUNE SYSTEM DYSFUNCTION
    Publication number: 20180214553
    Abstract: The present invention provides methods of treating an immune system dysfunction or conditions associated with soluble BCMA using gamma secretase modulators or inhibitors in order to both restore immune function and improve the efficacy of therapies directed against BCMA present on the pathogenic B cell.
    Type: Application
    Filed: July 22, 2016
    Publication date: August 2, 2018
    Inventor: James Richard BERENSON