Abstract: Quinazolines of the formula I in which R, R1, R2, R3, R4 and Y have the meaning indicated in Patent Claim 1, and their salts or solvates as glycoprotein IbIX antagonists.

Abstract: Disclosed are compounds of formula (I): wherein R3, R5, R7 and R8 are defined herein, which are useful as inhibitors SYK kinase and are thus useful for treating diseases resulting from inappropriate mast cell activation, which include allergic and inflammatory diseases. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.

Abstract: Disclosed are compounds of formula (I): wherein R3, R5, R7 and R8 are defined herein, which are useful as inhibitors SYK kinase and are thus useful for treating diseases resulting from inappropriate mast cell activation, which include allergic and inflammatory diseases. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.

Abstract: The present invention relates generally to automatically processing electronic documents. In one aspect, features and/or properties of words are identified from a set of training documents to aid in extracting information from documents to be processed. The features and/or properties relate to text of the words, position of the words and the relationship to other words. A classifier is developed to express these features and/or properties. During information extraction, documents are processed and analyzed based on the classifier and information is extracted based on correspondence of the documents and the features/properties expressed by the classifier.

Abstract: Disclosed are compounds of formula (I): wherein R3, R5, R7 and R8 are defined herein, which are useful as inhibitors SYK kinase and are thus useful for treating diseases resulting from inappropriate mast cell activation, which include allergic and inflammatory diseases. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.

Abstract: Quinazolines of the formula (I) in which R, R1, R2, R3, R4 and Y have the meaning indicated in Patent claim 1, and their salts or solvates as glycoprotein 1bIX antagonists.

Abstract: Disclosed are compounds of formula (I): wherein R3, R5, R7 and R8 are defined herein, which are useful as inhibitors SYK kinase and are thus useful for treating diseases resulting from inappropriate mast cell activation, which include allergic and inflammatory diseases. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.

Abstract: The invention addresses the current need for selective and potent protein tyrosine kinase inhibitors by providing potent inhibitors of c-fms kinase. The invention is directed to the novel compounds of Formula I: or a salt, stereoisomer, tautomer, crystalline, polymorph, amorphous, solvate, hydrate, ester, prodrug or metabolite form thereof, wherein A, Y, Z, R101 and R200 are described in the specification.

Abstract: Disclosed are compounds of formula (I): wherein R3, R5, R7 and R8 are defined herein, which are useful as inhibitors SYK kinase and are thus useful for treating diseases resulting from inappropriate mast cell activation, which include allergic and inflammatory diseases. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.

Abstract: Quinazolines of the formula I in which R, R1, R2, R3, R4 and Y have the meaning indicated in Patent Claim 1, and their salts or solvates as glycoprotein IbIX antagonists.

Abstract: The present invention relates to a method of automatically processing an electronic document for routing over a computer network. The method includes recognizing text in the document to identify a candidate address, accessing a collection of potential destinations and comparing the candidate address to the collection of potential destinations to determine a destination for the document.

Abstract: A tool has an adjustable lie angle, face angle, weight, and shaft length and is used by a golfer to adjust a putter to the optimal lie angle, face angle, weight and shaft length for that golfer. The tool head has a face plate and a sole disposed normal to one another. An angle member has a vertical wall disposed parallel to the face plate and a horizontal wall that overlies the sole. A hosel is pivotally mounted to the vertical wall and a first protractor is fixedly secured to the vertical wall. A marker on the hosel indicates the lie angle on the first protractor. A second protractor secured to the sole indicates a face angle when the shaft of the club is rotated about its axis. Weights are selectively added to the toe, heel, or mid-point of the putter head to determine an optimal weight and weight distribution.

Abstract: Systems and methods for encoding and decoding document images are disclosed. Document images are segmented into multiple layers according to a mask. The multiple layers are non-binary. The respective layers can then be processed and compressed separately in order to achieve better compression of the document image overall. A mask is generated from a document image. The mask is generated so as to reduce an estimate of compression for the combined size of the mask and multiple layers of the document image. The mask is then employed to segment the document image into the multiple layers. The mask determines or allocates pixels of the document image into respective layers. The mask and the multiple layers are processed and encoded separately so as to improve compression of the document image overall and to improve the speed of so doing. The multiple layers are non-binary images and can, for example, comprise a foreground image and a background image.

Abstract: A system and method facilitating document image compression utilizing a mask separating a foreground of a document image from a background is provided. The invention includes a pixel energy analyzer adapted to partition regions into a foreground and background. The invention further provides for a merge region component adapted to attempt to merge regions if the merged region would not exceed a threshold energy. Merged regions are partitioned into a new foreground and new background. Thereafter, a mask storage component stores the partitioning information in a binary mask.

Abstract: Quinazolinones of formula (I) in which R, R1, R2, R3, R4, Y, n and m have the meaning indicated in Patent claim 1, and their salts or solvates as glycoprotein IbIX antagonists

Abstract: A system and method facilitating image smoothing is provided. The invention includes an image processor having an image receptor and an image smoother. The invention provides for the image smoother to alter the value of a don't care pixel based, at least in part, upon a weighted average of care pixels.

Abstract: Quinazolines of the formula (I) in which R, R1, R2, R3, R4 and Y have the meaning indicated in Patent claim 1, and their salts or solvates as glycoprotein IbIX antagonists.

Abstract: A global optimization framework for optical character recognition (OCR) of low-resolution photographed documents that combines a binarization-type process, segmentation, and recognition into a single process. The framework includes a machine learning approach trained on a large amount of data. A convolutional neural network can be employed to compute a classification function at multiple positions and take grey-level input which eliminates binarization. The framework utilizes preprocessing, layout analysis, character recognition, and word recognition to output high recognition rates. The framework also employs dynamic programming and language models to arrive at the desired output.

Abstract: The present invention relates to a method of automatically processing an electronic document for routing over a computer network. The method includes recognizing text in the document to identify a candidate address, accessing a collection of potential destinations and comparing the candidate address to the collection of potential destinations to determine a destination for the document.

Abstract: The present invention relates generally to automatically processing electronic documents. In one aspect, features and/or properties of words are identified from a set of training documents to aid in extracting information from documents to be processed. The features and/or properties relate to text of the words, position of the words and the relationship to other words. A classifier is developed to express these features and/or properties. During information extraction, documents are processed and analyzed based on the classifier and information is extracted based on correspondence of the documents and the features/properties expressed by the classifier.