Abstract: The present patent application discloses the compounds according to Formula I shown below, or pharmaceutically acceptable salts thereof, wherein JB, n, R1, R2, R3, R4, R5, m and X as defined herein.

Abstract: A perimeter breach warning device includes a main body forming a firing bore therethrough, a holding protrusion at the first firing bore end, a firing pin assembly within and extending out from the firing bore, a primer within the firing bore at the second firing bore end, a safety nozzle, and a trip pin configured to be inserted into the trip pin bore of the shaft such that the spring of the firing pin assembly is compressed, wherein the spring is configured to decompress in response to removal of the trip pin, thereby causing the firing pin assembly to move within the firing bore towards the second firing bore end until the firing pin strikes the primer causing a primer explosion and the external shaft protrusion interfaces with the internal firing bore protrusion causing the firing pin assembly to stop moving towards the second firing bore end.

Abstract: The present disclosure relates to methods for determining the presence of or the amount of an analyte in a sample and to a slide for use in the method.

Abstract: A drive train for a wind-up injection device is described. The drive train includes a torsional energy storage adapted to be loaded or unloaded by a rotatable element, a rotatable user handle, a rotationally driveable expelling mechanism adapted to expel the liquid drug, and a clutch element coupled with the torsional energy storage via the rotatable element and including a ratchet for maintaining the rotatable element at one of a number of discrete angular positions against the torque of the torsional energy storage. The clutch element is adapted to transmit the torque from the user handle to the torsional energy storage, or alternatively from the torsional energy storage to the expelling mechanism. The ratchet is switchable from one position to an adjacent position by a torque transmitted from the user handle to the torsional energy storage. The drive train is adapted to dampen torque peaks visco-elastically and/or visco-frictionally.

Abstract: Disclosed herein are arylpyridinone compounds and compositions useful in the treatment of ITK mediated diseases, such as inflammation, having the structures of Formulas (I)-(IV): wherein the R groups, m, n, and X are as defined in the detailed description. Methods of inhibition of ITK activity in a human or animal subject are also provided.

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Abstract: Disclosed herein are tissue marking devices and methods that enables marking a target tissue more than 24 hours prior to surgery. The tissue marking device includes a hook assembly having a compressed configuration and a deployed configuration and a handle assembly for positioning the hook assembly in a targeted tissue. The hook assembly may include a hook body comprising at least two hooks and a thread connected to the hook body. The handle assembly may include a handle body, a needle having a lumen, and a stylet having a lumen.

Abstract: Techniques are disclosed relating to monitoring network traffic of an embeddable browser displayed by an application executing on a mobile computing device. In some embodiments, a first layer of the application manipulates one or more user interface elements displayed in the embeddable browser. The first layer of the application then detects network requests made by one or more application programming interfaces (APIs) executed by the embeddable browser in response to the manipulating. In some embodiments, the first layer sends to a second layer of the application results of observing network requests. In some embodiments, the second layer of the application displays, in real-time, information corresponding to the results of observing network requests.

Abstract: Techniques for determining a prediction probability associated with a disengagement event are discussed herein. A first prediction probability can include a probability that a safety driver associated with a vehicle (such as an autonomous vehicle) may assume control over the vehicle. A second prediction probability can include a probability that an object in an environment is associated the disengagement event. Sensor data can be captured and represented as a top-down representation of the environment. The top-down representation can be input to a machine learned model trained to output prediction probabilities associated with a disengagement event. The vehicle can be controlled based the prediction probability and/or the interacting object probability.

Abstract: The invention relates to a hair styling device, and in particular to a hair straightener. The hair styling device (10; 210) has a first arm (12; 212) and a second arm (14; 214), the first and second arms being moveable relative to one another between a closed or operative condition and an open or inoperative condition. The first member (12; 212) has a first heating panel (16; 116; 216) and the second member (14; 214) has a second heating panel (18; 118; 218). The heating panels (16, 18; 116, 118; 216, 218) are corrugated to increase the length of the path the hair must take between the heating panels. The first and second heating panels are spaced apart in the operative condition so as not to press or clamp the hair therebetween.

Abstract: A pallet cover suitable for use in covering at least a portion of a payload on a pallet and a kit for use in making the pallet cover. In one embodiment, the pallet cover includes a top wall, a front wall, a rear wall, a left side wall, and a right side wall, wherein the walls are detachably joined to one another. Each of the top wall, the front wall, the rear wall, the left side wall, and the right side wall includes a first fabric sheet and a second fabric sheet, the first and second fabric sheets being joined together to form a plurality of pockets. Each pocket may removably receive a temperature-control member containing a phase-change material. At least one of the top wall, the front wall, the rear wall, the left side wall and the right side wall may include a plurality of detachably joined portions.

Abstract: A network interface device comprises a streaming data processing path comprising a first data processing engine and hubs. A first scheduler associated with a first hub controls an output of data by the first hub to the first data processing engine and a second scheduler associated with a second hub controls an output of data by the second hub. The first hub is arranged upstream of the first data processing engine on the data processing path and is configured to receive data from a first upstream data path entity and from a first data processing entity implemented in programmable circuitry via a data ingress interface of the first hub. The first data processing engine is configured to receive data from the first hub, process the received data and output the processed data to the second hub arranged downstream of first data processing engine.

Abstract: A propeller blade angle control circuit for a turboprop engine includes a propeller control unit controlling a supply of oil to modify an angle of propeller blades, a pump located upstream of the propeller control unit and providing the supply of oil from an engine oil return system to the propeller control unit, and a flow regulator between the pump and the propeller control unit, the flow regulator modulating a supply of oil to the propeller control unit. A bypass, downstream of the pump in the propeller blade angle control circuit, has an inlet fluidly coupled to the pump. The bypass is operable between a closed position and an open position in which a portion of the oil supplied to the propeller control unit is diverted away from the propeller blade angle control circuit. The open position is engaged when an oil pressure reaches a predetermined threshold.

Abstract: A panel system includes a chassis holding one or more tray arrangements, which are each configured to receive one or more cassettes at two or more bays. The tray arrangements and cassettes cooperate to define a cassette sensor arrangement and a port occupancy sensor arrangement having separate interface points. The cassette sensor arrangement may include electronic memory storing physical layer information about the cassette. All active components of the port occupancy sensor arrangement are disposed on the tray while the electronic memories of the cassette sensor arrangement are stored on the cassettes.

Abstract: Apparatuses, systems, and techniques to indicate data dependencies. In at least one embodiment, one or more neural networks are used to generate one or more indicators of one or more data dependencies and one or more indicators of direction of the one or more data dependencies.

Abstract: A flexible multi-path RF adaptive tuning network switch architecture that counteracts impedance mismatch conditions arising from various combinations of coupled RF band filters, particularly in a Carrier Aggregation-based (CA) radio system. In one version, a digitally-controlled tunable matching network is coupled to a multi-path RF switch in order to provide adaptive impedance matching for various combinations of RF band filters. Optionally, some or all RF band filters include an associated digitally-controlled filter pre-match network to further improve impedance matching. In a second version, some or all RF band filters coupled to a multi-path RF switch include a digitally-controlled phase matching network to provide necessary per-band impedance matching. Optionally, a digitally-controlled tunable matching network may be included on the common port of the multi-path RF switch to provide additional impedance matching capability.

Abstract: A method of producing bioethanol in a bioethanol system and a control system for a bioethanol system is disclosed, the control system comprising a controller comprising one or more processors and an interface, wherein the one or more processors are configured to obtain a primary amino nitrogen (PAN) measurement; determine an input scheme based on the PAN measurement; and control one or more input devices of the bioethanol system according to the input scheme.

Abstract: A digital security system can store data associated with entities in resolver trees. If the digital security system determines that two resolver trees are likely representing the same entity, the digital security system can use a merge operation to merge the resolver trees into a single resolver tree that represents the entity. The single resolver tree can include a merge node indicating a merge identifier of the merge operation. Nodes containing information merged into the resolver tree from another resolver tree during the merge operation can be tagged with the corresponding merge identifier. Accordingly, if the merge operation is to be undone, for instance if subsequent information indicates that the entries are likely separate entities, the resolver tree can be unmerged and the nodes tagged with the merge identifier can be restored to a separate resolver tree.

Abstract: A seat assembly includes a seat portion having a frame assembly. A routing mechanism includes a plate member that is operably coupled to the frame assembly. The plate member includes a first portion having first and second raised portions spaced-apart from one another to define a channel therebetween. The routing mechanism further includes a connection assembly having upper and lower tabs spaced-apart from one another with a routing column assembly interconnecting the upper and lower tabs. A tether member includes a body portion that is routed through the routing mechanism, in that the body portion of the tether member is received in the channel of the routing mechanism and is wrapped around the routing column assembly and directed in forward direction.

Abstract: An example outdoor mounted device includes a first battery configured to operate at a low temperature range that at least includes negative 20 Celsius; a second battery configured to operate at a high temperature range; a temperature sensor; and processing circuitry configured to: determine, based on data received from the temperature sensors, a current temperature; responsive to determining that the current temperature is within the low temperature range, cause one or more components of the computing device to operate using electrical energy sourced from the first battery; and responsive to determining that the current temperature is within the high temperature range, cause the one or more components of the computing device to operate using electrical energy sourced from the second battery.