Abstract: An objective non-invasive method for quantifying itch comprising the steps of presenting a visual stimulus to a subject, wherein the visual stimulus comprises focusing the subject on itch; collecting psychophysiological data from subject while presenting the visual stimulus; using the psychophysiological data to objectively assess the therapeutic value of a treatment or a product.

Abstract: A noninvasive method for diagnosing skin health in a subject comprising collecting a skin sample/epithelial cell sample from the subject; detecting a level of one or more biomarkers selected from the group consisting of Myeloperoxidase and oxidized lipids in the epithelial cell sample/skin cell sample; diagnosing the subject as having oxidative stress and/or oxidative damage based on the level of a detected biomarker. Further, a noninvasive method for evaluating the efficacy of products for skin health.

Abstract: The present invention relates to a composition comprising an effective amount of a pyrithione or a polyvalent metal salt of a pyrithione, an effective amount of furametpyr and an effective amount of a surfactant including a surfactant with an anionic functional group.

Abstract: A personal care composition suitable for use as a non-aerosol shave composition comprising an anti-irritation agent; a lathering surfactant; a carrier comprising water; and optional adjunct ingredients such as lubricants.

Abstract: A composition dispensing device containing a moisturizing personal care composition suitable for use on wet skin.

Abstract: The present invention relates to a composition comprising an effective amount of zinc-containing layered material, an effective amount of a surfactant including a surfactant with an anionic functional group, wherein the zinc-containing layered material has a relative zinc lability of greater than about 15%. The present invention further relates to a composition according to Claim 1 wherein the composition further comprises an effective amount of a pyrithione or a polyvalent metal salt of a pyrithione.

Abstract: The present invention is directed to a method of inhibiting aconitase activity of fungal cells in an individual, the method comprising administering an inhibitor of aconitase activity to the fungal cell in an amount effective to inhibit activity of aconitase by said fungal cells.

Abstract: The present invention is directed to a personal care composition comprising an effective amount of a pyrithione or a polyvalent metal salt of a pyrithione; an effective amount of an iron chelator or a material which chelates iron; wherein the combination of the iron chelator and the pyrithione or a polyvalent metal salt of a pyrithione has a fractional inhibitor concentration of less than or equal to 1.

Abstract: A method for measuring of histamine in an epidermis comprising applying an adhesive article to an epithelium of a mammal; allowing for adherence of epithelial cells to the adhesive article; removing the adhesive article from the epithelium of the mammal; preparing the adhesive article using standard laboratory methods for extraction; extracting histamine from the epithelial cells adhered to said adhesive article; measuring histamine from the epithelial cells adhered to said adhesive article; determining the amount of histamine in the epithelial cells as compared to a baseline sample. Further, a method of objectively measuring the perception of itch in mammals and wherein there is a reduction in histamine from a baseline level which is directly proportional to a reduction in an itch perception.

Abstract: An aerosol shave composition, preferably a post foaming shave gel, comprising a hydrophobic agent, such as a silicone, in the form of a microdroplet having a particle size from about 0.15 microns to about 10 microns and an anti-irritation agent such as zinc pyrithione, and a method of making.

Abstract: A shave preparation comprising water; one or more lipophilic skin conditioning agents; one or more thickening agents; one or more emulsifying agents; and one or more lubricants, and an anti-irritation agent such as zinc pyrithione.

Abstract: A personal care composition comprising an anti-irritation agent such as a zinc pyrithione, a zinc salt or a combination thereof.

Abstract: A composition dispensing device containing a composition comprising an anti-irritation agent such as zinc pyrithione. which is preferably thick and viscous yet remains clear or translucent.

Abstract: Disclosed are compositions comprising an effective amount of a zinc containing material having an aqueous solubility within the composition of less than about 25% by weight at 25° C.; from about 5% to about 50% of a surfactant; and from about 40% to about 95% water; wherein the pH of the composition is greater than about 7. Further disclosed are compositions comprising an effective amount of a zinc containing material having an aqueous solubility within the composition of less than about 25% by weight at 25° C.; from about 5% to about 50% of a surfactant; and from about 0.1% to about 5% of a zinc ionophoric material; from about 40% to about 95% water; and wherein the pH of the composition is greater than about 7.

Abstract: A method for reducing irritation on an intimate area comprising: applying an intimate cleansing product to the intimate area; rinsing the intimate cleansing product from the intimate area; applying a shave preparation to the intimate area; shaving the intimate area; wherein the intimate cleansing product comprises a malodor active.

Abstract: A method for treating malodor on an intimate area comprising: applying an intimate cleansing product to the intimate area; rinsing the intimate cleansing product from the intimate area; and applying an antiperspirant to the intimate area; wherein the intimate cleansing product comprises a malodor active.

Abstract: A personal care composition suitable for use as a non-aerosol shave composition comprising an anti-irritation agent; a lathering surfactant; a carrier comprising water; and optional adjunct ingredients such as lubricants.

Abstract: The present invention relates to personal care compositions, especially those shave preparation article and skin care articles which are in the form of a porous dissolvable solid substrate having a surface resident coating comprising at least one skin treatment active. The present invention can deliver a consumer benefit as well as allow for separation of any incompatible actives in the substrate versus the coating.

Abstract: A personal care composition which is preferably a post-foaming gel, said composition comprising an anti-irritation agent; a water dispersible surface active agent, of a carrier comprising water; and optionally a lubricant.

Abstract: A method for measuring of histamine in an epidermis comprising applying an adhesive article to an epithelium of a mammal; allowing for adherence of epithelial cells to the adhesive article; removing the adhesive article from the epithelium of the mammal; preparing the adhesive article using standard laboratory methods for extraction; extracting histamine from the epithelial cells adhered to said adhesive article; measuring histamine from the epithelial cells adhered to said adhesive article; determining the amount of histamine in the epithelial cells as compared to a baseline sample. Further, a method of objectively measuring the perception of itch in mammals and wherein there is a reduction in histamine from a baseline level which is directly proportional to a reduction in an itch perception.