Abstract: This invention relates to the restoration of adipose tissue inpatients with lipodystrophy characterised by a defective gene. A heterologous nucleic acid that encodes a therapeutic gene product is administered to the patient. The therapeutic gene product may be functional version of the protein encoded by the defective gene or an RNA molecule that inhibits expression from the defective gene. Methods for the treatment of lipodystrophy and the amelioration of metabolic dysfunction associated with lipodystrophy are provided, along with agents and compositions for use in such methods.

Abstract: A system for cooling superconducting materials used for magnetization of magnets disposed within a cylindrical structure, the system including a first tubing system for allowing a cooling gas to interact with a high-field strength superconducting material to thermosiphon-cool the high-field strength superconducting material, a second tubing system for allowing a cooling gas to interact with a low-field strength superconducting material to thermosiphon-cool the low-field strength superconducting material, and a cooling gas in liquefied form configured to flow through the first tubing system and/or the second tubing system. An outlet of the first tubing system and an outlet of the second tubing system are located at a same location on a surface of the cylindrical structure. A method for cool superconducting materials used for magnetization of magnets disposed within a cylindrical structure is also disclosed.

Abstract: A system for cooling superconducting materials used for magnetization of magnets disposed within a cylindrical structure, the system including a first tubing system for allowing a cooling gas to interact with a high-field strength superconducting material to thermosiphon-cool the high-field strength superconducting material, a second tubing system for allowing a cooling gas to interact with a low-field strength superconducting material to thermosiphon-cool the low-field strength superconducting material, and a cooling gas in liquefied form configured to flow through the first tubing system and/or the second tubing system. An outlet of the first tubing system and an outlet of the second tubing system are located at a same location on a surface of the cylindrical structure. A method for cool superconducting materials used for magnetization of magnets disposed within a cylindrical structure is also disclosed.