Patents by Inventor James RUSH

James RUSH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240132606
    Abstract: The present invention relates to silent Fc variants of anti-CD40 antibodies and compositions and methods of use of said antibodies for treating pathological disorders such as autoimmune and inflammatory disorders and/or for preventing or reducing the risk of graft rejection in transplantation.
    Type: Application
    Filed: July 25, 2023
    Publication date: April 25, 2024
    Inventors: Christoph HEUSSER, James RUSH, Karen VINCENT
  • Patent number: 11950394
    Abstract: The disclosure relates to an apparatus and method for liquid cooling of an electronic component. A housing includes an insertion slot and defines at least one component chamber for carrying the electronic component. A fluid inlet and fluid outlet are provided on the housing. A liquid coolant circuit passes through the housing at least from the inlet to the outlet.
    Type: Grant
    Filed: October 12, 2021
    Date of Patent: April 2, 2024
    Assignee: GE Aviation Systems LLC
    Inventors: Brian Magann Rush, Christopher James Kapusta, David Richard Esler, Liang Yin, Richard Anthony Eddins, Judd Everett Swanson, Liqiang Yang
  • Patent number: 11804009
    Abstract: Described herein are systems, methods, and computer readable media for performing data conversion on sensor data to obtain modified sensor data that is formatted/structured appropriately for downstream processes that rely on the sensor data as input. The sensor data can include point cloud data captured by a LiDAR, for example. A grid structure and corresponding grid characteristics can be determined and the sensor data can be converted to grid-based sensor data by associating the grid structure and its characteristics with the sensor data. Generating the grid-based sensor data can include reformatting the point cloud data to superimpose the grid structure and its grid characteristics onto the point cloud data. Various downstream processing that cannot feasibly be performed on the raw sensor data can then be performed efficiently on the modified grid-based sensor data by virtue of the grid structure imbuing the sensor data with spatial proximity information.
    Type: Grant
    Filed: December 28, 2021
    Date of Patent: October 31, 2023
    Assignee: Pony AI Inc.
    Inventors: Pingfan Meng, Michael Wu, Brian James Rush
  • Patent number: 11780927
    Abstract: The disclosure relates to methods, treatment regimens, uses, kits and therapies for preventing graft rejection in solid organ transplantation, by employing anti-CD40 antibodies.
    Type: Grant
    Filed: April 11, 2019
    Date of Patent: October 10, 2023
    Assignee: NOVARTIS AG
    Inventors: Pascal Espie, Boerje Haraldsson, James Rush
  • Publication number: 20230203176
    Abstract: The present invention relates to methods, treatment regimens, uses, kits and therapies for prevention of graft rejection in solid organ transplantation, particularly solid organ xenotransplantation, by administering an anti-CD40 antibody or a combination of an anti-CD40 antibody and an anti-C5 antibody.
    Type: Application
    Filed: September 16, 2022
    Publication date: June 29, 2023
    Inventors: Guido JUNGE, James RUSH, Andrew B. ADAMS, Alfred Joseph TECTOR, III
  • Publication number: 20220204635
    Abstract: The present invention relates to silent Fc variants of anti-CD40 antibodies and compositions and methods of use of said antibodies for treating pathological disorders such as autoimmune and inflammatory disorders and/or for preventing or reducing the risk of graft rejection in transplantation.
    Type: Application
    Filed: August 16, 2021
    Publication date: June 30, 2022
    Inventors: Christoph HEUSSER, James RUSH, Karen VINCENT
  • Publication number: 20220195061
    Abstract: The disclosure relates to methods, treatment regimens, uses, kits and therapies for treating T1DM, by employing anti-CD40 antibodies.
    Type: Application
    Filed: May 6, 2020
    Publication date: June 23, 2022
    Inventors: Pascal ESPIE, Allison GOLDFINE, Rainer MUSSMANN, James RUSH
  • Publication number: 20220122319
    Abstract: Described herein are systems, methods, and computer readable media for performing data conversion on sensor data to obtain modified sensor data that is formatted/structured appropriately for downstream processes that rely on the sensor data as input. The sensor data can include point cloud data captured by a LiDAR, for example. A grid structure and corresponding grid characteristics can be determined and the sensor data can be converted to grid-based sensor data by associating the grid structure and its characteristics with the sensor data. Generating the grid-based sensor data can include reformatting the point cloud data to superimpose the grid structure and its grid characteristics onto the point cloud data. Various downstream processing that cannot feasibly be performed on the raw sensor data can then be performed efficiently on the modified grid-based sensor data by virtue of the grid structure imbuing the sensor data with spatial proximity information.
    Type: Application
    Filed: December 28, 2021
    Publication date: April 21, 2022
    Inventors: Pingfan Meng, Michael Wu, Brian James Rush
  • Publication number: 20220098315
    Abstract: The disclosure relates to methods, treatment regimens, uses, kits and therapies for treating hidradenitis suppurativa, by employing CD40 antagonists, such as anti-CD40 antibodies.
    Type: Application
    Filed: January 9, 2020
    Publication date: March 31, 2022
    Inventors: Pascal ESPIE, Christian LOESCHE, Lukas ROTH, James RUSH, Grazyna WIECZOREK
  • Patent number: 11210845
    Abstract: Described herein are systems, methods, and computer readable media for performing data conversion on sensor data to obtain modified sensor data that is formatted/structured appropriately for downstream processes that rely on the sensor data as input. The sensor data can include point cloud data captured by a LiDAR, for example. A grid structure and corresponding grid characteristics can be determined and the sensor data can be converted to grid-based sensor data by associating the grid structure and its characteristics with the sensor data. Generating the grid-based sensor data can include reformatting the point cloud data to superimpose the grid structure and its grid characteristics onto the point cloud data. Various downstream processing that cannot feasibly be performed on the raw sensor data can then be performed efficiently on the modified grid-based sensor data by virtue of the grid structure imbuing the sensor data with spatial proximity information.
    Type: Grant
    Filed: April 22, 2020
    Date of Patent: December 28, 2021
    Assignee: Pony AI Inc.
    Inventors: Pingfan Meng, Michael Wu, Brian James Rush
  • Publication number: 20210335033
    Abstract: Described herein are systems, methods, and computer readable media for performing data conversion on sensor data to obtain modified sensor data that is formatted/structured appropriately for downstream processes that rely on the sensor data as input. The sensor data can include point cloud data captured by a LiDAR, for example. A grid structure and corresponding grid characteristics can be determined and the sensor data can be converted to grid-based sensor data by associating the grid structure and its characteristics with the sensor data. Generating the grid-based sensor data can include reformatting the point cloud data to superimpose the grid structure and its grid characteristics onto the point cloud data. Various downstream processing that cannot feasibly be performed on the raw sensor data can then be performed efficiently on the modified grid-based sensor data by virtue of the grid structure imbuing the sensor data with spatial proximity information.
    Type: Application
    Filed: April 22, 2020
    Publication date: October 28, 2021
    Inventors: Pingfan Meng, Michael Wu, Brian James Rush
  • Patent number: 11124578
    Abstract: The present invention relates to silent Fc variants of anti-CD40 antibodies and compositions and methods of use of said antibodies for treating pathological disorders such as autoimmune and inflammatory disorders and/or for preventing or reducing the risk of graft rejection in transplantation.
    Type: Grant
    Filed: April 30, 2019
    Date of Patent: September 21, 2021
    Assignee: NOVARTIS AG
    Inventors: Christoph Heusser, James Rush, Karen Vincent
  • Publication number: 20210079107
    Abstract: The disclosure relates to methods, treatment regimens, uses, kits and therapies for preventing graft rejection in solid organ transplantation, by employing anti-CD40 antibodies.
    Type: Application
    Filed: April 11, 2019
    Publication date: March 18, 2021
    Inventors: Pascal ESPIE, Boerje HARALDSSON, James RUSH
  • Publication number: 20200087409
    Abstract: The present invention relates to silent Fc variants of anti-CD40 antibodies and compositions and methods of use of said antibodies for treating pathological disorders such as autoimmune and inflammatory disorders and/or for preventing or reducing the risk of graft rejection in transplantation.
    Type: Application
    Filed: April 30, 2019
    Publication date: March 19, 2020
    Applicant: Novartis AG
    Inventors: Christoph HEUSSER, James RUSH, Karen VINCENT
  • Patent number: 10323096
    Abstract: The present invention relates to silent Fc variants of anti-CD40 antibodies and compositions and methods of use of said antibodies for treating pathological disorders such as autoimmune and inflammatory disorders and/or for preventing or reducing the risk of graft rejection in transplantation.
    Type: Grant
    Filed: October 26, 2017
    Date of Patent: June 18, 2019
    Assignee: Novartis AG
    Inventors: Christoph Heusser, James Rush, Karen Vincent
  • Publication number: 20190153111
    Abstract: The disclosure relates to methods, treatment regimens, uses, kits and therapies for treating Sjögren's syndrome, by employing anti-CD40 antibodies.
    Type: Application
    Filed: November 1, 2018
    Publication date: May 23, 2019
    Inventors: Pascal Espie, Peter Gergely, James Rush
  • Publication number: 20180118843
    Abstract: The present invention relates to silent Fc variants of anti-CD40 antibodies and compositions and methods of use of said antibodies for treating pathological disorders such as autoimmune and inflammatory disorders and/or for preventing or reducing the risk of graft rejection in transplantation.
    Type: Application
    Filed: October 26, 2017
    Publication date: May 3, 2018
    Applicant: Novartis AG
    Inventors: Christoph HEUSSER, James RUSH, Karen VINCENT
  • Patent number: 9828433
    Abstract: The present invention relates to silent Fc variants of anti-CD40 antibodies and compositions and methods of use of said antibodies for treating pathological disorders such as autoimmune and inflammatory disorders and/or for preventing or reducing the risk of graft rejection in transplantation.
    Type: Grant
    Filed: May 25, 2017
    Date of Patent: November 28, 2017
    Assignee: Novartis AG
    Inventors: Christoph Heusser, James Rush, Karen Vincent
  • Publication number: 20170267772
    Abstract: The present invention relates to silent Fc variants of anti-CD40 antibodies and compositions and methods of use of said antibodies for treating pathological disorders such as autoimmune and inflammatory disorders and/or for preventing or reducing the risk of graft rejection in transplantation.
    Type: Application
    Filed: May 25, 2017
    Publication date: September 21, 2017
    Applicant: Novartis AG
    Inventors: Christoph HEUSSER, James RUSH, Karen VINCENT
  • Patent number: 9688768
    Abstract: The present invention relates to silent Fc variants of anti-CD40 antibodies and compositions and methods of use of said antibodies for treating pathological disorders such as autoimmune and inflammatory disorders and/or for preventing or reducing the risk of graft rejection in transplantation.
    Type: Grant
    Filed: November 19, 2015
    Date of Patent: June 27, 2017
    Assignee: Novartis AG
    Inventors: Christoph Heusser, James Rush, Karen Vincent