Abstract: An interventional guiding sheath system can include an inner sheath, an outer sheath, and a filter located between the inner sheath and outer sheath. The filter can be expandable such that it opens to secure the guiding sheath system within a vessel of a patient during an interventional procedure. The inner sheath can include a mesh or other type of opening such that when the filter is collapsed back against the inner sheath, any debris collected by the filter during the procedure can pass through the inner sheath for aspiration out of the vessel. Additionally, a dilator can be used with the inner sheath for, among other things, aiding in placement of the device. The dilator can also be provided with a mesh, a recess, or other type of opening to allow any debris that is collected by the filter to either be stored by the dilator or aspirated from the dilator.