Patents by Inventor James Russell Pruitt

James Russell Pruitt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oxygen or sulfur containing heteroaromatics as factor Xa inhibitors
    Patent number: 6962935
    Abstract: The present application describes oxygen and sulfur containing heteroaromatics and derivatives thereof of formula I: or pharmaceutically acceptable salt or prodrug forms thereof, wherein J is O or S and D may be C(?NH)NH2, which are useful as inhibitors of factor Xa.
    Type: Grant
    Filed: April 9, 2003
    Date of Patent: November 8, 2005
    Assignee: Bristol-Myers Squibb Pharma Company
    Inventors: James Russell Pruitt, John Matthew Fevig, Mimi Lifen Quan, Donald Joseph Phillip Pinto
  • Oxygen or sulfur containing heteroaromatics as factor Xa inhibitors
    Publication number: 20040073029
    Abstract: The present application describes oxygen and sulfur containing heteroaromatics and derivatives thereof of formula I: 1
    Type: Application
    Filed: April 9, 2003
    Publication date: April 15, 2004
    Inventors: James Russell Pruitt, John Matthew Fevig, Mimi Lifen Quan, Donald Joseph Phillip Pinto
  • Thiazoles as factor Xa inhibitors
    Patent number: 6569874
    Abstract: The present application describes oxygen and sulfur containing heteroaromatics and derivatives thereof of formula I: or pharmaceutically acceptable salt or prodrug forms thereof, wherein J is O or S and D may be C(═NH)NH2, which are useful as inhibitors of factor Xa.
    Type: Grant
    Filed: November 17, 2000
    Date of Patent: May 27, 2003
    Assignee: Bristol-Myers Squibb Company
    Inventors: James Russell Pruitt, John Matthew Fevig, Mimi Lifen Quan, Donald Joseph Phillip Pinto
  • Nitrogen containing heteroaromatics as factor Xa inhibitors
    Patent number: 6548512
    Abstract: The present application describes nitrogen containing heteroaromatics and derivatives thereof of formula I: or pharmaceutically acceptable salt or prodrug forms thereof, wherein J is N or NH and D may be C(═NH)NH2, which are useful as inhibitors of factor Xa.
    Type: Grant
    Filed: January 27, 2000
    Date of Patent: April 15, 2003
    Assignee: Bristol-Myers Squibb Pharma Company
    Inventors: Donald Joseph Phillip Pinto, James Russell Pruitt, Joseph Cacciola, John Matthew Fevig, Qi Han, Michael James Orwat, Mimi Lifen Quan, Karen Anita Rossi
  • 6-membered aromatics as factor Xa inhibitors
    Patent number: 6426346
    Abstract: The present application describes 6-membered aromatics of formula I: or pharmaceutically acceptable salt forms thereof, wherein D may be CH2NH2 or C(═NH)NH2, which are useful as inhibitors of factor Xa.
    Type: Grant
    Filed: February 15, 2000
    Date of Patent: July 30, 2002
    Assignee: Bristol - Myers Squibb Pharma Company
    Inventors: James Russell Pruitt, Donald Joseph Phillip Pinto, Mimi Lifen Ouan, Ruth Richmond Wexler
  • Phenyl-isoxazoles as factor XA Inhibitors
    Patent number: 6187797
    Abstract: The present application describes oxygen and sulfur containing heteroaromatics and derivatives thereof of formula or pharmaceutically acceptable salt or prodrug forms thereof, wherein J is O or S and D may be C(═NH)NH2, which are useful as inhibitors of factor Xa.
    Type: Grant
    Filed: December 22, 1997
    Date of Patent: February 13, 2001
    Assignee: Dupont Pharmaceuticals Company
    Inventors: James Russell Pruitt, John Matthew Fevig, Mimi Lifen Quan, Donald Joseph Phillip Pinto
  • 6-membered aromatics as factor Xa inhibitors
    Patent number: 6060491
    Abstract: The present application describes 6-membered aromatics of formula I: ##STR1## or pharmaceutically acceptable salt forms thereof, wherein D may be CH.sub.2 NH.sub.2 or C(.dbd.NH)NH.sub.2, which are useful as inhibitors of factor Xa.
    Type: Grant
    Filed: June 18, 1998
    Date of Patent: May 9, 2000
    Assignee: Dupont Pharmaceuticals
    Inventors: James Russell Pruitt, Donald Joseph Phillip Pinto, Mimi Lifen Quan, Ruth Richmond Wexler
  • Nitrogen containing heteroaromatics as factor Xa inhibitors
    Patent number: 6020357
    Abstract: The present application describes nitrogen containing heteroaromatics and derivatives thereof of formula I: ##STR1## or pharmaceutically acceptable salt or prodrug forms thereof, wherein J is N or NH and D may be C(.dbd.NH)NH.sub.2, which are useful as inhibitors of factor Xa.
    Type: Grant
    Filed: December 22, 1997
    Date of Patent: February 1, 2000
    Assignee: DuPont Pharmaceuticals Company
    Inventors: Donald Joseph Phillip Pinto, James Russell Pruitt, Joseph Cacciola, John Matthew Fevig, Qi Han, Michael James Orwat, Mimi Lifen Quan, Karen Anita Rossi
  • Isoxazoline, isothiazoline and pyrazoline factor Xa inhibitors
    Patent number: 5939418
    Abstract: Isoxazolines, isothiazolines and pyrazolines which are inhibitors of Factor Xa, pharmaceutical compositions containing these compounds, and methods of using these compounds as anticoagulant agents for treatment and prevention of thromboembolic disorders. The compounds can be represented by the formula: ##STR1## where X is O, S or NR.sup.15.
    Type: Grant
    Filed: December 17, 1996
    Date of Patent: August 17, 1999
    Assignee: The DuPont Merck Pharmaceutical Company
    Inventors: Mimi Lifen Quan, John Wityak, Robert Anthony Galemmo, Jr., Petrus F. W. Stouten, James Russell Pruitt, Donald J. P. Pinto