Patents by Inventor James S. Cullor

James S. Cullor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20030086947
    Abstract: This invention relates to the diagnosis and prevention of ungulate diseases caused by the spirochete bacteria Treponema. The invention specifically relates to isolated cultures of this spirochete and isolated nucleic acids and proteins.
    Type: Application
    Filed: March 1, 2000
    Publication date: May 8, 2003
    Applicant: TOWNSEND AND TOWNSEND AND CREW
    Inventors: Richard L. Walker, Deryck H. Read, David W. Hird, Rance B. Lefebvre, Steven L. Berry, James S. Cullor, Hank M. Lefler
  • Patent number: 6329136
    Abstract: Methods of inactivating pathogens in biological materials, and biological materials that have been so treated, are provided. The inactivation methodology employs UV radiation, by devices such as lasers, to cause inactivation of pathogens, such as viruses.
    Type: Grant
    Filed: October 13, 1999
    Date of Patent: December 11, 2001
    Assignee: The Regents of the University of California
    Inventors: Manuel C. Lagunas-Solar, Bennie I. Osburn, James S. Cullor
  • Patent number: 6287575
    Abstract: This invention relates to the diagnosis and prevention of ungulate diseases caused by the spirochete bacteria Treponema. The invention specifically relates to isolated cultures of this spirochete and isolated nucleic acids and proteins.
    Type: Grant
    Filed: October 3, 1997
    Date of Patent: September 11, 2001
    Assignee: The Regents of the University of California
    Inventors: Richard L. Walker, Deryck H. Read, David W. Hird, Rance B. Lefebvre, Steven L. Berry, James S. Cullor, Hank M. Lefler
  • Patent number: 6211148
    Abstract: The present invention provides a new family of cysteine-rich antimicrobial peptides isolated from bovine neutrophils herein named beta defensins. Thirteen structurally homologous peptides were purified to homogeneity from a granule-rich cytoplasmic fraction of purified blood neutrophils. These antimicrobial compounds are useful in human and veterinary medicine, and as agents in agricultural, food science, and industrial applications.
    Type: Grant
    Filed: December 11, 1997
    Date of Patent: April 3, 2001
    Assignee: The Regents of the University of California
    Inventors: Michael E. Selsted, James S. Cullor
  • Patent number: 6096323
    Abstract: This invention relates to the diagnosis and prevention of ungulate diseases caused by the spirochete bacteria Treponema. The invention specifically relates to isolated cultures of this spirochete and isolated nucleic acids and proteins.
    Type: Grant
    Filed: November 12, 1998
    Date of Patent: August 1, 2000
    Assignee: The Regents of the University of California
    Inventors: Richard L. Walker, Deryck H. Read, David W. Hird, Rance B. Lefebvre, Steven L. Berry, James S. Cullor, Hank M. Lefler
  • Patent number: 5821224
    Abstract: The present invention provides a new family of cysteine-rich antimicrobial peptides isolated from bovine neutrophils herein named beta defensins. Thirteen structurally homologous peptides were purified to homogeneity from a granule-rich cytoplasmic fraction of purified blood neutrophils. These antimicrobial compounds are useful in human and veterinary medicine, and as agents in agricultural, food science, and industrial applications.
    Type: Grant
    Filed: December 13, 1994
    Date of Patent: October 13, 1998
    Assignee: Regents of the University of California
    Inventors: Michael E. Selsted, James S. Cullor
  • Patent number: 5459235
    Abstract: The present invention provides a new family of cysteine-rich antimicrobial peptides isolated from bovine neutrophils herein named beta defensins. Thirteen structurally homologous peptides were purified to homogeneity from a granule-rich cytoplasmic fraction of purified blood neutrophils. These antimicrobial compounds are useful in human and veterinary medicine, and as agents in agricultural, food science, and industrial applications.
    Type: Grant
    Filed: March 19, 1993
    Date of Patent: October 17, 1995
    Assignee: The Regents of the University of California
    Inventors: Michael E. Selsted, James S. Cullor
  • Patent number: 5324716
    Abstract: The invention provides a broad spectrum antimicrobial compound that includes a tryptophan-rich peptide exhibiting antimicrobial activity. A method of microbicidal inhibition or microbistatic inhibition of microbial growth is also provided. The method includes administering to an environment capable of sustaining microbial growth a microbicidally or microbistatically effective amount of a tryptophan-rich peptide exhibiting antimicrobial activity.
    Type: Grant
    Filed: June 14, 1991
    Date of Patent: June 28, 1994
    Assignee: Regents of the University of California
    Inventors: Michael E. Selsted, James S. Cullor
  • Patent number: 5242902
    Abstract: A method for treating cutaneous and corneal wounds as well as certain microbial-related diseases comprises topically applying a defensin peptide to the affected tissue. The compositions comprise a natural, synthetic, or analog defensin molecule having both a mitogenic activity capable of stimulating cell growth and an antimicrobial activity capable of inhibiting the growth of a wide variety of pathogens. In addition to therapeutic use, the defensins are useful as mitogens in cell and tissue culture media.
    Type: Grant
    Filed: September 6, 1989
    Date of Patent: September 7, 1993
    Assignee: The Regents of the University of California
    Inventors: Christopher J. Murphy, Ted W. Reid, Mark J. Mannis, Bradley A. Foster, James S. Cullor, Michael E. Selsted, Robert I. Lehrer, Tomas Ganz
  • Patent number: 4987079
    Abstract: An improved method and apparatus is disclosed for adding fluids to, or removing fluids from, a body part or organ of an animal which minimizes animal trauma and permits rapid, easy, repeated fluid or low viscosity gel transfers. The apparatus includes a tubular fluid-conveying element adapted for fixed connection to the animal, along with a flexible fluid conduit connected between the element and a specific internal body part or organ, such as a cow's uterus. In use, a syringe is employed to introduce or remove fluids from the body part, through the tubular element and connected conduit. The invention is especially adapted for introducing and recovering cell lines producing monoclonal antibodies or other biologically active products in large mammals, and fascilitates monitoring of antibody production as well as administration of nutrients to enhance cell line growth.
    Type: Grant
    Filed: August 4, 1989
    Date of Patent: January 22, 1991
    Assignees: Wilbur D. Smith, James Cullor, James S. Cullor, Gary W. Cullor
    Inventor: James S. Cullor
  • Patent number: 4491126
    Abstract: An improved method and apparatus is disclosed for adding fluids to, or removing fluids from, a body part or organ of an animal which minimizes animal trauma and permits rapid, easy, repeated fluid or low viscosity gels transfers. The apparatus includes a valve assembly having a tubular fluid-conveying element adapted for fixed connection to the animal, along with a fluid conduit connected between the valve element and a specific internal body part or organ, such as a cow's uterus. In use, a syringe is employed to introduce or remove fluids from the body part, through the valve assembly and connected conduit. The invention is especially adapted for introducing, recovering cell lines producing monoclonal antibodies or other biologically active products in large mammals, and facilitates monitoring of antibody production as well as administration of nutrients to enhance cell line growth.
    Type: Grant
    Filed: January 6, 1982
    Date of Patent: January 1, 1985
    Assignees: Wilbur D. Smith, James Cullor, James S. Cullor, Gary W. Cullor
    Inventor: James S. Cullor