Patents by Inventor James S. Goydos

James S. Goydos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATION THERAPY USING RILUZOLE TO ENHANCE TUMOR SENSITIVITY TO IONIZING RADIATION
    Publication number: 20240042033
    Abstract: Disclosed is a method of treating a tumor in a patient, comprising (a) administering riluzole in an amount effective to sensitize the tumor cells to ionizing radiation, and (b) irradiating the tumor cells with ionizing radiation in a dose effective to reduce tumor cell growth. The method can further comprise administering an effective amount of one or more additional therapeutic agents.
    Type: Application
    Filed: October 18, 2023
    Publication date: February 8, 2024
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Atif J. Khan, Suzie Chen, James S. Goydos, Bruce G. Haffty
  • Combination therapy using riluzole to enhance tumor sensitivity to ionizing radiation
    Patent number: 11813331
    Abstract: Disclosed is a method of treating a tumor in a patient, comprising (a) administering riluzole in an amount effective to sensitize the tumor cells to ionizing radiation, and (b) irradiating the tumor cells with ionizing radiation in a dose effective to reduce tumor cell growth. The method can further comprise administering an effective amount of one or more additional therapeutic agents.
    Type: Grant
    Filed: December 8, 2021
    Date of Patent: November 14, 2023
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Atif J. Khan, Suzie Chen, James S. Goydos, Bruce G. Haffty
  • COMBINATION THERAPY USING RILUZOLE TO ENHANCE TUMOR SENSITIVITY TO IONIZING RADIATION
    Publication number: 20220096636
    Abstract: Disclosed is a method of treating a tumor in a patient, comprising (a) administering riluzole in an amount effective to sensitize the tumor cells to ionizing radiation, and (b) irradiating the tumor cells with ionizing radiation in a dose effective to reduce tumor cell growth. The method can further comprise administering an effective amount of one or more additional therapeutic agents.
    Type: Application
    Filed: December 8, 2021
    Publication date: March 31, 2022
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Atif J. Khan, Suzie Chen, James S. Goydos, Bruce G. Haffty
  • Combination therapy using riluzole to enhance tumor sensitivity to ionizing radiation
    Patent number: 11229704
    Abstract: Disclosed is a method of treating a tumor in a patient, comprising (a) administering riluzole in an amount effective to sensitize the tumor cells to ionizing radiation, and (b) irradiating the tumor cells with ionizing radiation in a dose effective to reduce tumor cell growth. The method can further comprise administering an effective amount of one or more additional therapeutic agents.
    Type: Grant
    Filed: November 20, 2020
    Date of Patent: January 25, 2022
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Atif J. Khan, Suzie Chen, James S. Goydos, Bruce G. Haffty
  • COMBINATION THERAPY USING RILUZOLE TO ENHANCE TUMOR SENSITIVITY TO IONIZING RADIATION
    Publication number: 20210138067
    Abstract: Disclosed is a method of treating a tumor in a patient, comprising (a) administering riluzole in an amount effective to sensitize the tumor cells to ionizing radiation, and (b) irradiating the tumor cells with ionizing radiation in a dose effective to reduce tumor cell growth. The method can further comprise administering an effective amount of one or more additional therapeutic agents.
    Type: Application
    Filed: November 20, 2020
    Publication date: May 13, 2021
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Atif J. Khan, Suzie Chen, James S. Goydos, Bruce G. Haffty
  • Combination therapy using riluzole to enhance tumor sensitivity to ionizing radiation
    Patent number: 10864271
    Abstract: Disclosed is a method of treating a tumor in a patient, comprising (a) administering riluzole in an amount effective to sensitize the tumor cells to ionizing radiation, and (b) irradiating the tumor cells with ionizing radiation in a dose effective to reduce tumor cell growth. The method can further comprise administering an effective amount of one or more additional therapeutic agents.
    Type: Grant
    Filed: February 15, 2013
    Date of Patent: December 15, 2020
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Atif Jalees Khan, Suzie Chen, James S. Goydos, Bruce G. Haffty
  • Methods and compositions for treating cancer
    Patent number: 8835473
    Abstract: The present invention provides methods of treating cancer using 2-amino-6-trifluoromethoxybenzothiazole (riluzole). In one aspect, the present invention provides methods of reducing cancer cell growth. In another aspect, the present invention provides a method of inducing apoptosis in a cancer cell. In another aspect, the present invention provides a method of reducing the growth of a glutamate-releasing tumor.
    Type: Grant
    Filed: September 15, 2009
    Date of Patent: September 16, 2014
    Assignee: Rutgers, The State University of New Jersey
    Inventors: James S. Goydos, Suzie Chen
  • METHODS AND COMPOSITIONS FOR TREATING CANCER
    Publication number: 20100221246
    Abstract: The present invention provides methods of treating cancer using 2-amino-6-trifluoromethoxybenzothiazole (riluzole). In one aspect, the present invention provides methods of reducing cancer cell growth. In another aspect, the present invention provides a method of inducing apoptosis in a cancer cell. In another aspect, the present invention provides a method of reducing the growth of a glutamate-releasing tumor.
    Type: Application
    Filed: September 15, 2009
    Publication date: September 2, 2010
    Applicants: UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY, RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: James S. Goydos, Suzie Chen
  • Methods and compositions for treating melanoma
    Patent number: 7691377
    Abstract: A method for inhibiting melanoma cell growth in a patient by administering to the patient a therapeutically effective amount of a glutamate release inhibitor, a GRM1 antagonist, or a combination thereof
    Type: Grant
    Filed: September 14, 2007
    Date of Patent: April 6, 2010
    Assignee: Rutgers, The State University of New Jersey
    Inventors: James S. Goydos, Suzie Chen
  • METHODS AND COMPOSITIONS FOR TREATING MELANOMA
    Publication number: 20080124333
    Abstract: A method for inhibiting melanoma cell growth in a patient by administering to the patient a therapeutically effective amount of a glutamate release inhibitor, a GRM 1 antagonist, or a combination thereof
    Type: Application
    Filed: September 14, 2007
    Publication date: May 29, 2008
    Applicants: UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY, RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: James S. Goydos, Suzie Chen