Patents by Inventor James S. Metcalf

James S. Metcalf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions comprising a metal and L-serine, and uses thereof
    Patent number: 11278512
    Abstract: Presented herein are compositions comprising L-serine, or a precursor, derivative or conjugate thereof, and a non-toxic metal, such as zinc. Compositions disclosed herein can be used for the prevention and treatment of neurodegenerative diseases, or related symptoms thereof.
    Type: Grant
    Filed: August 21, 2020
    Date of Patent: March 22, 2022
    Assignee: BRAIN CHEMISTRY LABS
    Inventors: Paul Alan Cox, Sandra Anne Banack, James S. Metcalf, Rachael Dunlop
  • COMPOSITIONS COMPRISING A METAL AND L-SERINE, AND USES THEREOF
    Publication number: 20210052533
    Abstract: Presented herein are compositions comprising L-serine, or a precursor, derivative or conjugate thereof, and a non-toxic metal, such as zinc. Compositions disclosed herein can be used for the prevention and treatment of neurodegenerative diseases, or related symptoms thereof.
    Type: Application
    Filed: August 21, 2020
    Publication date: February 25, 2021
    Inventors: Paul Alan COX, Sandra Anne BANACK, James S. METCALF, Rachael DUNLOP
  • Immunoassay for detection of neurotoxic amino acid associated with neurological disorders
    Patent number: 8603753
    Abstract: An immunoassay for screening a sample to detect the presence of ?-N-methylamino-L-alanine (BMAA) is disclosed. Antibodies specific for BMAA are disclosed. Antibodies that bind to BMAA on immunoblots are disclosed. Immunoassays and kits to detect the presence of BMAA in a sample by contacting the sample with an antibody that binds to BMAA, and detecting the antibody bound to the sample, are disclosed. Immunoassays and kits for screening for the presence of BMAA in a subject by analyzing a tissue sample obtained from the subject to detect the present of BMAA in the tissue sample, where the presence of BMAA in the tissue sample indicates exposure of the subject to an environmental source of BMAA, are disclosed. Immunoassays and kits for detecting an environmental source of BMAA, by screening an environmental sample to detect the presence of BMAA in the sample, wherein the presence of a detectable amount of BMAA in the sample indicates the sample is an environmental source of BMAA, are disclosed.
    Type: Grant
    Filed: July 2, 2009
    Date of Patent: December 10, 2013
    Assignees: The Institute for Ethnomedicine, The University of Dundee
    Inventors: Paul Alan Cox, James S. Metcalf, Geoffrey A. Codd
  • IMMUNOASSAY FOR DETECTION OF NEUROTOXIC AMINO ACID ASSOCIATED WITH NEUROLOGICAL DISORDERS
    Publication number: 20110223624
    Abstract: An immunoassay for screening a sample to detect the presence of ?-N-methylamino-L-alanine (BMAA) is disclosed. Antibodies specific for BMAA are disclosed. Antibodies that bind to BMAA on immunoblots are disclosed. Immunoassays and kits to detect the presence of BMAA in a sample by contacting the sample with an antibody that binds to BMAA, and detecting the antibody bound to the sample, are disclosed. Immunoassays and kits for screening for the presence of BMAA in a subject by analyzing a tissue sample obtained from the subject to detect the present of BMAA in the tissue sample, where the presence of BMAA in the tissue sample indicates exposure of the subject to an environmental source of BMAA, are disclosed. Immunoassays and kits for detecting an environmental source of BMAA, by screening an environmental sample to detect the presence of BMAA in the sample, wherein the presence of a detectable amount of BMAA in the sample indicates the sample is an environmental source of BMAA, are disclosed.
    Type: Application
    Filed: July 2, 2009
    Publication date: September 15, 2011
    Applicant: THE INSTITUTE FOR ETHNOMEDICINE
    Inventors: Paul Alan Cox, James S. Metcalf, Geoffrey A. Codd