Abstract: Systems, devices, and methods discussed herein can be for validating a position of a wirelessly powered electrostimulation device while the device is implanted in body tissue. A method can include situating the electrostimulation device in tissue and before an affixation mechanism of the electrostimulation device is deployed to maintain an implanted position of the electrostimulation device, and while electrodes of the device are in contact with the tissue, performing electrical testing of the electrostimulation device to determine whether the electrostimulation from the electrostimulation device evokes a specified response from the body that contains the tissue.

Abstract: In order to improve both spatial resolution and sensitivity for brain research and clinical activity, we have designed a combined PET/MRI insert for brain scanning, referred to herein as a “BrainPET insert” that can be fit onto and into a suitable MRI system. The BrainPET Insert comprises, in order, a receive (Rx) coil positioned within and adjacent to a transmit (Tx) coil and a PET ring, wherein both the Rx coil and the Tx coil are within the PET ring.

Abstract: Embodiments regard innovations for implantable electrostimulation devices and corresponding systems that operate using or contain the implantable electrostimulation devices. A system can include an implantable electrostimulation device. The system can further include an introducer configured to deliver the electrostimulation device to a target location inside a patient body. The introducer can comprise a migration mitigation component configured to couple with the electrostimulation device.

Abstract: Described herein is a positron emission tomography (PET) detector array that has a plurality of detector elements, with each detector element mounted on a resilient, rigid support surface. A detector element movement system is connected to each rigid support surface, so that each detector element can be moved independently. This allows for the relative position of the individual detectors to be changed during imaging so that the imaging window can be increased or decreased during imaging, thereby allowing for improved, better resolution imaging of smaller volumes if desired.

Abstract: Systems, devices, and methods discussed herein can be for validating a position of a wirelessly powered electrostimulation device while the device is implanted in body tissue. A method can include situating the electrostimulation device in tissue and before an affixation mechanism of the electrostimulation device is deployed to maintain an implanted position of the electrostimulation device, and while electrodes of the device are in contact with the tissue, performing electrical testing of the electrostimulation device to determine whether the electrostimulation from the electrostimulation device evokes a specified response from the body that contains the tissue.

Abstract: Described herein is a method to measure the position of the PET System using the MRI, through the use of MRI coils and fiducials. This approach offers a route to automated calibration which is more flexible than other approaches. This method of position measurement is useful for example in systems which have moving or removeable PET readout board systems or moving or removeable PET scintillator blocks.

Abstract: In order to improve both spatial resolution and sensitivity for brain research and clinical activity, we have designed a combined PET/MRI insert for brain scanning, referred to herein as a “BrainPET insert” that can be fit onto and into a suitable MRI system. The BrainPET Insert comprises, in order, a receive (Rx) coil positioned within and adjacent to a transmit (Tx) coil and a PET ring, wherein both the Rx coil and the Tx coil are within the PET ring.

Abstract: Systems, devices, and methods discussed herein include wireless midfield transmitters and implantable receiver devices. A midfield transmitter can be configured to provide signals outside of tissue that give rise to propagating signals inside of tissue. The present subject matter includes a protection circuit for a transmitter device, a layered transmitter device, an implantable receiver device, implantation and extraction methods, test and assembly methods, and the like. In an example, a protection circuit includes a first control circuit to receive an RF drive signal and conditionally provide an output signal to an antenna. A second control circuit can generate a control signal based on the antenna output signal and/or information about the RF drive signal. A gain circuit can provide the RF drive signal to the first control circuit. The gain circuit can change an amplitude of the RF drive signal based on the control signal from the second control circuit.

Abstract: Described herein is multiplexing scintillation blocks, called interblock muxing. Specifically, the start of an annihilation event is recorded and assigned a time stamp while the energy of the entire event is recorded separately. All events occurring at a series of multiplexed scintillation blocks are reported to a processor which distinguishes individual events and assigns the start of each event with its corresponding energy, thereby allowing for cheaper and more efficient processing of events during PET imaging.

Abstract: A pendant breast imaging system that operates with a MRI system and which allows a planar gamma camera breast imaging system to be positioned away from the breast area while MRI imaging is occurring, and which then moves into breast imaging position after MRI imaging is complete, and which can again be removed from the breast area to allow intervention to occur is described. It may use various collimator or scintillator materials and designs.

Abstract: Radiation therapy of a lesion within a patient is guided to take into account movement of the lesion caused by respiration and/or cardiac effects by using MRI or other imaging system suitable for locating the lesion to image the patient while on the treatment support and using a PET detection system responsive to a radiation source preferentially taken up by the lesion and registered with the MRI so as to monitor movement of the lesion in real time and thus guide the beam of the RT.

Abstract: Described herein is a gamma camera imaging system in which a plurality of gamma cameras or multiheads are attached at a front face thereof to the outer surface of a flexible substrate. The flexible substrate is capable of forming an inner concave surface which in use is arranged to fit over or around a body part to be analyzed.

Abstract: Described herein is a gamma camera imaging system in which a plurality of gamma cameras or multiheads are attacked at a front face thereof to the outer surface of a flexible substrate. The flexible substrate is capable of forming an inner concave surface which in use is arranged to fit over or around a body part to be analyzed.

Abstract: Radiation therapy of a lesion within a patient is guided to take into account movement of the lesion caused by respiration and/or cardiac effects by using MRI or other imaging system suitable for locating the lesion to image the patient while on the treatment support and using a gamma imaging system responsive to a radiation source preferentially taken up by the lesion and registered with the MRI so as to monitor movement of the lesion in real time and thus guide the beam of the RT.

Abstract: Described herein is the use of gamma cameras in the fringe field of the MRI system. Specifically, an MR image of the breast with lesion identification is first produced. Then, a gamma camera is attached to the existing breast immobilization system for generating one or more gamma images of the breast. The gamma camera is then removed from the breast immobilization system, and a breast biopsy is performed. The gamma camera can then be used to image the biopsy cores that have been removed from the patient in order to verify that the biopsy cores are radioactive, that the biopsy cores extend from one end of the lesion to the other and have a radioactive profile in which the tip is not as radioactive as the middle, and in which the ratio of amount of radioactivity in the middle of the core to the amount of radioactivity that is present in the tip of the core can be expressed as a ratio.

Abstract: A pendant breast imaging system that operates with a MRI system and which allows a planar gamma camera breast imaging system to be positioned away from the breast area while MRI imaging is occurring, and which then moves into breast imaging position after MRI imaging is complete, and which can again be removed from the breast area to allow intervention to occur is described. It may use various collimator or scintillator materials and designs.

Abstract: A method of scanning breast tissue involves inserting an imaging element into a breast via a carrier inserted into a breast duct. The imaging element may be for example a receiver, a transmitter or a mirror. A signal is transmitted between one imaging element within the breast duct and a second imaging element outside the breast.

Abstract: A patient imaging system includes a patient support table, an MRI system including a cylindrical magnet and a PET system including positron detectors mounted in a ring. The magnet defines a cylindrical bore for receiving the patient on the table where the magnet is mounted for rotation about a vertical axis on a slew ring carried on rails allowing longitudinal movement. The PET ring is mounted in the bore for longitudinal movement. The quench tube for the magnet passes through the slew ring with a rotary union at the axis. The shielding covers include a fixed upper part and a lower part which rotates about the axis with the magnet. The magnet is arranged in a two or three room diagnostic configuration in which a holding bay houses the magnet and the diagnostic patients are organized in the three rooms each cooperating with the magnet bay as the magnet is rotated.

Abstract: A patient imaging system includes a patient support table, an MRI system including a cylindrical magnet and a PET system including positron detectors mounted in a ring. The magnet defines a cylindrical bore for receiving the patient on the table where the magnet is mounted for rotation about a vertical axis on a slew ring carried on rails allowing longitudinal movement. The PET ring is mounted in the bore for longitudinal movement. The quench tube for the magnet passes through the slew ring with a rotary union at the axis. The shielding covers include a fixed upper part and a lower part which rotates about the axis with the magnet. The magnet is arranged in a two or three room diagnostic configuration in which a holding bay houses the magnet and the diagnostic patients are organized in the three rooms each cooperating with the magnet bay as the magnet is rotated.

Abstract: A wide bandwidth, high power amplifier system for amplifying a signal in a radio frequency (RF) system in a specific bandwidth within the frequency range from 1 MHz to 100 GHz. The system includes a number of amplifier modules and an equal number of input transformers connected in series, with each input transformer providing an input signal to one amplifier module. It also includes an equal number of output transformers connected in series with each output transformer receiving an input signal from one amplifier module. The series of input transformers, the series of output transformers and the amplifier modules each provide an impedance matched approximately to the impedance of the RF system.