Patents by Inventor James Sebastian Italia

James Sebastian Italia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROTEIN DERIVATIVES CONTAINING UNNATURAL AMINO ACIDS AND BRANCHED LINKERS
    Publication number: 20240000941
    Abstract: The invention relates generally to protein derivatives containing molecules (e.g., payloads) conjugated to unnatural amino acids (UAAs) by branched linkers, and methods of making and using such protein derivatives.
    Type: Application
    Filed: November 24, 2021
    Publication date: January 4, 2024
    Inventor: James Sebastian Italia
  • STABLE CELL LINES FOR SITE-SPECIFIC INCORPORATION OF UNNATURAL AMINO ACIDS
    Publication number: 20230313129
    Abstract: The invention relates generally to engineered tRNAs, engineered aminoacyl-tRNA synthetases, unnatural amino acids, and cells comprising the same, and their use in the incorporation of unnatural amino acids into proteins.
    Type: Application
    Filed: August 6, 2021
    Publication date: October 5, 2023
    Inventors: James Sebastian Italia, Zhi Li
  • PROTEINS CONTAINING MULTIPLE, DIFFERENT UNNATURAL AMINO ACIDS AND METHODS OF MAKING AND USING SUCH PROTEINS
    Publication number: 20220403438
    Abstract: The invention relates generally to methods of producing a protein comprising a first unnatural amino acid (UAA) and a second, different UAA, and proteins comprising a first UAA and a second, different UAA.
    Type: Application
    Filed: October 8, 2020
    Publication date: December 22, 2022
    Inventors: Yunan Zheng, James Sebastian Italia, Abhishek Chatterjee
  • AMINOACYL-TRNA SYNTHETASES AND CELL LINES FOR SITE-SPECIFIC INCORPORATION OF UNNATURAL AMINO ACIDS
    Publication number: 20220325269
    Abstract: The invention relates generally to engineered tRNAs, engineered aminoacyl-tRNA synthetases, unnatural amino acids, and cells comprising the same, and their use in the incorporation of unnatural amino acids into proteins.
    Type: Application
    Filed: August 7, 2020
    Publication date: October 13, 2022
    Inventor: James Sebastian Italia