Abstract: Described herein are elongate device for modifying tissue having a plurality of flexibly connected rungs or links, and methods of using them, including methods of using them to decompress stenotic spinal tissue. These devices may be included as part of a system for modifying tissue. In general, these devices include a plurality of blades positioned on (or formed from) rungs that are flexibly connected. The rungs are typically rigid, somewhat flat and wider than they are long (e.g., rectangular). The rungs may be arranged, ladder like, and may be connected by a flexible connector substrate or between two or more cables. Different sized rungs may be used. The blades (on the rungs) may be arranged in a staggered arrangement. A tissue-collection or tissue capture element (e.g., chamber, bag, or the like) may be used to collect the cut or modified tissue. In some variations the tissue modification devices may have a non-linear axial shape, or may be converted from a first axial shape to a second axial shape.

Abstract: Described herein are elongate devices for modifying tissue having a plurality of flexibly connected rungs or links, and methods of using them, including methods of using them to decompress stenotic spinal tissue. These devices may be included as part of a system for modifying tissue. In general, these devices include a plurality of blades positioned on (or formed from) rungs that are flexibly connected. The rungs are typically rigid, somewhat flat and wider than they are long (e.g., rectangular). The rungs may be arranged, ladder like, and may be connected by a flexible connector substrate or between two or more cables. Different sized rungs may be used. The blades (on the rungs) may be arranged in a staggered arrangement. A tissue-collection or tissue capture element may be used to collect the cut or modified tissue.

Abstract: A prosthetic disc for insertion between adjacent vertebrae includes upper and lower plates and a core having upper and lower curved surfaces disposed between the plates. At least one of the plates and/or the core includes a resilient material for absorbing shock or other forces applied by vertebrae. Optionally, resilient support members may be disposed within the resilient material to connect two portions of a plate or the core. Such support members may be springs, cylinders, wires or other resilient structures. The resilient material is held within the core or plate(s) via a surrounding retaining structure, such as a membrane. The resilient material disposed in one or more components of the prosthetic disc provides for shock absorption.

Abstract: A prosthetic disc for insertion between adjacent vertebrae includes upper and lower plates and a core having upper and lower curved surfaces disposed between the plates. At least one of the plates and/or the core includes a resilient material for absorbing shock or other forces applied by vertebrae. Optionally, resilient support members may be disposed within the resilient material to connect two portions of a plate or the core. Such support members may be springs, cylinders, wires or other resilient structures. The resilient material is held within the core or plate(s) via a surrounding retaining structure, such as a membrane. The resilient material disposed in one or more components of the prosthetic disc provides for shock absorption.

Abstract: A prosthesis system comprises plates that can be positioned against vertebrae and a selected resilient core that can be positioned between the plates to allow the plates to articulate. The selected resilient core can be chosen from a plurality of cores in response to patient characteristics, such as age and/or intervertebral mobility, such that the prosthesis implanted in the patient is tailored to the needs of the patient. The plurality of cores may comprise cores with different resiliencies, and one of the cores can be selected such that the upper and lower plates articulate with the desired shock absorbing resiliency and/or maximum angle of inclination when the one selected core is positioned between the plates.

Abstract: Described herein are elongate device for modifying tissue having a plurality of flexibly connected rungs or links, and methods of using them, including methods of using them to decompress stenotic spinal tissue. These devices may be included as part of a system for modifying tissue. In general, these devices include a plurality of blades positioned on (or formed from) rungs that are flexibly connected. The rungs are typically rigid, somewhat flat and wider than they are long (e.g., rectangular). The rungs may be arranged, ladder like, and may be connected by a flexible connector substrate or between two or more cables. Different sized rungs may be used. The blades (on the rungs) may be arranged in a staggered arrangement. A tissue-collection or tissue capture element (e.g., chamber, bag, or the like) may be used to collect the cut or modified tissue. In some variations the tissue modification devices may have a non-linear axial shape, or may be converted from a first axial shape to a second axial shape.

Abstract: A prosthesis system comprises plates that can be positioned against vertebrae and a selected resilient core that can be positioned between the plates to allow the plates to articulate. The selected resilient core can be chosen from a plurality of cores in response to patient characteristics, such as age and/or intervertebral mobility, such that the prosthesis implanted in the patient is tailored to the needs of the patient. The plurality of cores may comprise cores with different resiliencies, and one of the cores can be selected such that the upper and lower plates articulate with the desired shock absorbing resiliency and/or maximum angle of inclination when the one selected core is positioned between the plates.

Abstract: A prosthetic disc for insertion between adjacent vertebrae includes upper and lower plates and a core having upper and lower curved surfaces disposed between the plates. At least one of the plates and/or the core includes a resilient material for absorbing shock or other forces applied by vertebrae. Optionally, resilient support members may be disposed within the resilient material to connect two portions of a plate or the core. Such support members may be springs, cylinders, wires or other resilient structures. The resilient material is held within the core or plate(s) via a surrounding retaining structure, such as a membrane. The resilient material disposed in one or more components of the prosthetic disc provides for shock absorption.

Abstract: The present invention provides inflatable porous implants, such as grafts, stent-grafts, and bladders, as well as methods and kits for drug delivery. In particular, the grafts and stent-grafts of the present invention provide for the delivery of a therapeutic agent into a flow conduit in the body. The inflatable porous implants provide for direct delivery of larger, more precise dosages of drugs over longer administration periods into the body. Moreover, these inflatable porous implants are often flexible when inserted and have a low profile delivery configuration for easy placement. The implants of the present invention further provide a mechanical or structural function in addition to drug delivery in a single integrated structure.

Abstract: A recessed lighting fixture including a housing having spaced apart generally vertical walls defining an interior and an open bottom end. The walls have generally vertical slots through them. The fixture has lip means for maintaining the bottom end of the housing against a lower surface of a ceiling. The fixture further includes a plurality of mounting members disposed on an exterior surface of the wall means. Each of these mounting members has a first end, an outwardly curved elongated body portion made of resilient material and a second end. The first end of each mounting member is attached to the housing near the bottom end of the housing. The second end of the mounting member extends at least partially through the slot into the interior of the fixture so that at least a portion of the second end is accessible from the interior through the open bottom end.

Abstract: A device is disclosed for cutting a portion of a patella during knee surgery in which the articular surface of the patella along with a portion of the bone of the patella is cut away for implantation of a prosthesis. The device disclosed provides a fixed clamping member and an adjustable clamping member which clamp the patella and space from the patella a support surface for an oscillating saw used in the cutting of the patella. The precise plane of cut is provided by the use of a placement aid which is used according to the method of the present invention. The placement aid positions the support surface a precise depth below the articular surface of the patella during the clamping procedure, which clamping procedure also horizontally levels the support surface and the device so that all cuts through the patella are made in a perfectly horizontal plane.