Abstract: Methods for controlled segregation of blocks of information encoded in the sequence of a biopolymer, such as nucleic acids and polypeptides, with rapid retrieval based on multiply addressing nanostructured data have been developed. In some embodiments, sequence controlled polymer memory objects include data-encoded biopolymers of any length or form encapsulated by natural or synthetic polymers and including one or more address tags. The sequence address labels are used to associate or select memory objects for sequencing read-out, enabling organization and access of distinct memory objects or subsets of memory objects using Boolean logic. In some embodiments, a memory object is a single-stranded nucleic acid scaffold strand encoding bit stream information that is folded into a nucleic acid nanostructure of arbitrary geometry, including one or more sequence address labels. Methods for controlled degradation of biopolymer-encoded blocks of information in the memory objects are also developed.

Abstract: Methods for the automated template-free synthesis of user-defined sequence controlled biopolymers using microfluidic devices are described. The methods facilitate simultaneous synthesis of up to thousands of uniquely addressed biopolymers from the controlled movement and combination of regents as fluid droplets using microfluidic and EWOD-based systems. In some forms, biopolymers including nucleic acids, peptides, carbohydrates, and lipids are synthesized from step-wise assembly of building blocks based on a user-defined sequence of droplet movements. In some forms, the methods synthesize uniquely addressed nucleic acids of up to 1,000 nucleotides in length. Methods for adding, removing and changing barcodes on biopolymers are also provided. Biopolymers synthesized according to the methods, and libraries and databases thereof are also described. Modified biopolymers, including chemically modified nucleotides and biopolymers conjugated to other molecules are described.

Abstract: Some embodiments of the invention provide a novel network architecture for deploying guest clusters (GCs) including workload machines for a tenant (or other entity) within an availability zone. The novel network architecture includes a virtual private cloud (VPC) deployed in the availability zone (AZ) that includes a centralized routing element that provides access to a gateway routing element of the AZ. In some embodiments, the centralized routing element provides a set of services for packets traversing a boundary of the VPC. The services, in some embodiments, include load balancing, firewall, quality of service (QoS) and may be stateful or stateless. Guest clusters are deployed within the VPC and use the centralized routing element of the VPC to access the gateway routing element of the AZ.

Abstract: A multi-axis system (30) for positioning a workpiece measuring sensor (54) on a metrology machine. Preferably, each sensor is positionable via a system comprising movement along and/or about at least linear directions/axes (X, Z, A, B) so as to control linear and/or rotational movement of a sensor automatically to a predetermined position without operator intervention. The multi-axis positioning system allows faster setup times when a workpiece or tooling on a machine is changed.

Abstract: An example virtualized computing system includes: a host cluster having hosts and a virtualization layer executing on hardware platforms of the hosts, the virtualization layer supporting execution of virtual machines (VMs); an orchestration control plane integrated with the virtualization layer, the orchestration control plane including a master server executing in a first VM of the VMs; guest cluster infrastructure software (GCIS) executing in the master server, the GCIS configured to create a set of objects defining a container orchestration cluster, and manage lifecycles of second VMs of the VMs based on state of the set of objects; and guest software executing in the second VMs to implement the container orchestration cluster as a guest cluster of the host cluster, the guest software having components that interface with the GCIS.

Abstract: A probe calibration method and calibration artifact (30, 70) whereby calibration can be performed without the use of machine axes capable of three dimensional positioning of a probe relative to a calibration sphere (40). The method includes a plurality of calibration spheres fixed in relation to one another via a rigid structure comprising a calibration artifact body (30, 70). The spheres are mounted such that each will be sensed by the probe at some position of a machine axis (W, N). In other words, the spheres lie in the region swept out by the sensor field of view (8, 78) over the movement of the machine axis. The calibration spheres are located at known positions (A, B, C) and the calibration artifact body is designed such that it may be mounted in a known location in place of a work piece.

Abstract: This disclosure describes a computer implemented method for receiving authentication credentials identifying a user; identifying computing systems for which the user is authorized access to; and transmitting tokens granting access to the identified computing systems. In some embodiments, no two tokens of the transmitted tokens grants access to the same one of the identified computing systems. The user typically has access to a management tool configured to manage the transmission of the received tokens to the corresponding computing systems, thereby granting the user the ability to have seamless access to any of the computing systems associated with the user's authenticated identity.

Abstract: A method for removing fouling from a pipeline includes determining the location of fouling in the pipeline. Once determined, the method further includes installing a hot tap in the pipeline. A flex conduit is inserted into the pipeline through the hot tap and a treatment fluid is flowed into the pipeline through the conduit. The treatment fluid is used to remove the fouling from the pipeline. Once the fouling is sufficiently removed, the flexible conduit is removed from the pipeline.

Abstract: An example virtualized computing system includes a host cluster having hosts and a virtualization layer executing on hardware platforms of the hosts, the virtualization layer supporting execution of virtual machines (VMs), the VMs including pod VMs, the pod VMs including container engines supporting execution of containers in the pod VMs; and an orchestration control plane integrated with the virtualization layer, the orchestration control plane including a master server configured to manage the pod VMs and first VMs of the VMs. The virtualized computing system further includes a guest cluster executing in the first VMs and managed by the orchestration control plane, the guest cluster including a guest master server configured to, in cooperation with the master server, deploy first pods in the pod VMs.

Abstract: This disclosure describes a computer implemented method for receiving authentication credentials identifying a user; identifying computing systems for which the user is authorized access to; and transmitting tokens granting access to the identified computing systems. In some embodiments, no two tokens of the transmitted tokens grants access to the same one of the identified computing systems. The user typically has access to a management tool configured to manage the transmission of the received tokens to the corresponding computing systems, thereby granting the user the ability to have seamless access to any of the computing systems associated with the user's authenticated identity.

Abstract: An example method of checking compatibility of a guest cluster executing as a virtual extension of a host cluster having an orchestration control plane managing the guest cluster, the host cluster being part of a software defined data center (SDDC), is described.

Abstract: An example virtualized computing system includes a host cluster having hosts and a virtualization layer executing on hardware platforms of the hosts, the virtualization layer supporting execution of virtual machines (VMs), the VMs including pod VMs, the pod VMs including container engines supporting execution of containers in the pod VMs; and an orchestration control plane integrated with the virtualization layer, the orchestration control plane including a master server configured to manage the pod VMs and first VMs of the VMs. The virtualized computing system further includes a guest cluster executing in the first VMs and managed by the orchestration control plane, the guest cluster including a guest master server configured to, in cooperation with the master server, deploy first pods in the pod VMs.

Abstract: A virtualized computing system according to an example includes: a host cluster having hosts and a virtualization layer executing on hardware platforms of the hosts, the virtualization layer supporting execution of virtual machines (VMs); a container image registry configured to manage container images for deploying containers in the host cluster; an orchestration control plane integrated with the virtualization layer, the orchestration control plane including a master server executing in a first VM of the VMs, the master server configured to manage image secrets based on accounts in the container image registry; and a guest cluster, managed by the orchestration control plane and executing in second VMs of the VMs, the guest cluster configured to receive the image secrets from the master server and access the container image registry using the image secrets.

Abstract: A probe calibration method and calibration artifact (30, 70) whereby calibration can be performed without the use of machine axes capable of three dimensional positioning of a probe relative to a calibration sphere (40). The method includes a plurality of calibration spheres fixed in relation to one another via a rigid structure comprising a calibration artifact body (30, 70). The spheres are mounted such that each will be sensed by the probe at some position of a machine axis (W, N). In other words, the spheres lie in the region swept out by the sensor field of view (8, 78) over the movement of the machine axis. The calibration spheres are located at known positions (A, B, C) and the calibration artifact body is designed such that it may be mounted in a known location in place of a work piece.

Abstract: A subsea chemical injection system and method for injecting chemicals into a hydrocarbon production assembly adjacent the seabed wherein a seawater volume flowmeter is utilized to measure seawater pumped through the system and a chemical subsea mass flowmeter is used to measure a chemical injected into the seawater, where the chemical subsea mass flowmeter measures the chemical at a pressure less than the seawater pumped through the system. Based on the chemical subsea mass flowmeter measurement, the flowrate of a chemical injected into the seawater can be adjusted to a predetermined setpoint corresponding to the flowrate of seawater pumped through the system. The chemical subsea mass flowmeter includes a Coriolis tube and chemical injection process pump housed within a pressure vessel. The subsea chemical injection system may be carried on a skid.

Abstract: A method and machine comprising at least one non-contact sensor (52) on a functional testing platform (50) for workpiece inspection and/or measurement. The inclusion of at least one non-contact sensor on the functional testing platform results in the combination of two machine platforms into a single machine and provides the user with measurement characteristics of both methods, functional and analytical, saving significant cycle time and significant space.

Abstract: Some embodiments of the invention provide a novel network architecture for deploying guest clusters (GCs) including workload machines for a tenant (or other entity) within an availability zone. The novel network architecture includes a virtual private cloud (VPC) deployed in the availability zone (AZ) that includes a centralized routing element that provides access to a gateway routing element of the AZ. In some embodiments, the centralized routing element provides a set of services for packets traversing a boundary of the VPC. The services, in some embodiments, include load balancing, firewall, quality of service (QoS) and may be stateful or stateless. Guest clusters are deployed within the VPC and use the centralized routing element of the VPC to access the gateway routing element of the AZ.

Abstract: A virtualized computing system according to an example includes: a host cluster having hosts and a virtualization layer executing on hardware platforms of the hosts, the virtualization layer supporting execution of virtual machines (VMs); a container image registry configured to manage container images for deploying containers in the host cluster; an orchestration control plane integrated with the virtualization layer, the orchestration control plane including a master server executing in a first VM of the VMs, the master server configured to manage image secrets based on accounts in the container image registry; and a guest cluster, managed by the orchestration control plane and executing in second VMs of the VMs, the guest cluster configured to receive the image secrets from the master server and access the container image registry using the image secrets.

Abstract: An example virtualized computing system includes a host cluster having hosts and a virtualization layer executing on hardware platforms of the hosts, the virtualization layer supporting execution of virtual machines (VMs), the VMs including pod VMs, the pod VMs including container engines supporting execution of containers in the pod VMs; and an orchestration control plane integrated with the virtualization layer, the orchestration control plane including a master server configured to manage the pod VMs and first VMs of the VMs. The virtualized computing system further includes a guest cluster executing in the first VMs and managed by the orchestration control plane, the guest cluster including a guest master server configured to, in cooperation with the master server, deploy first pods in the pod VMs.

Abstract: A subsea chemical injection system and method for injecting chemicals into a hydrocarbon production assembly adjacent the seabed wherein a seawater volume flowmeter is utilized to measure seawater pumped through the system and a chemical subsea mass flowmeter is used to measure a chemical injected into the seawater, where the chemical subsea mass flowmeter measures the chemical at a pressure less than the seawater pumped through the system. Based on the chemical subsea mass flowmeter measurement, the flowrate of a chemical injected into the seawater can be adjusted to a predetermined setpoint corresponding to the flowrate of seawater pumped through the system. The chemical subsea mass flowmeter includes a Coriolis tube and chemical injection process pump housed within a pressure vessel. The subsea chemical injection system may be carried on a skid.