Abstract: A composition for administration of a therapeutically effective dose of a topoisomerase inhibitor I or topoisomerase I/II inhibitor is described. The composition includes liposomes having an outer surface and an inner surface defining an aqueous liposome compartment, and being composed of a vesicle-forming lipid and of a vesicle-forming lipid derivatized with a hydrophilic polymer to form a coating of hydrophilic polymer chains on both the inner and outer surfaces of the liposomes. Entrapped in the liposomes is the topoisomerase inhibitor at a concentration of at least about 0.10 ?mole drug per ?mole lipid.

Abstract: A composition for administration of a therapeutically effective dose of a topoisomerase inhibitor I or topoisomerase I/II inhibitor is described. The composition includes liposomes having an outer surface and an inner surface defining an aqueous liposome compartment, and being composed of a vesicle-forming lipid and of a vesicle-forming lipid derivatized with a hydrophilic polymer to form a coating of hydrophilic polymer chains on both the inner and outer surfaces of the liposomes. Entrapped in the liposomes is the topoisomerase inhibitor at a concentration of at least about 0.10 ?mole drug per ?mole lipid.

Abstract: Apparatus and method for providing DMA transfers between an adapter card with or with out DMA capabilities and a system CPU with DMA capabilities. An adapter DMA controller circuit resides between the system CPU and the adapter card. This adapter DMA controller allows the system to run in immediate mode which allows the system CPU to talk to the adapter card as if the adapter DMA controller was not there. The system can also run in DMA mode. In this mode the system CPU sets up the system DMA controller and the adapter DMA controller. The adapter DMA controller takes over sending or receiving data to the adapter card and then requesting a DMA transfer with the system DMA controller. The transfer of data between the adapter DMA controller and the adapter does not use any system CPU resources such as the data and address busses. The system CPU is free to use the system resources to continue operation.

Abstract: A canine vest having ballistic panels has an outer covering including a longitudinally extending elastic panel. Apertures are provided for a dog's front legs and front and rear ballistic panels are removably secured to an inner face of the cover in addition opposed side panels of ballistic material secured the inner face of the cover. A top closure is provided preferably a zipper type fastener and additionally a rappelling ring may be provided adjacent the top closure.