Abstract: A drive mechanism for a drug delivery device which can be switched between a normal operation state and a reset state comprises of a housing having a proximal end and a distal end, a rotation member which is adapted to rotate in a first direction and in a second direction with respect to the housing, a drive member, wherein in the normal operation state the rotation member is coupled with the drive member so that the drive member follows rotational movement of the rotation member in the second direction, a piston rod, wherein in the normal operation state the piston rod is displaced in a distal direction with respect to the housing when the drive member rotates in the second direction with respect to the housing, a stop member, wherein in the normal operation state the stop member is coupled with the drive member so that the stop member prevents rotational movement of the drive member with respect to the housing in the first direction, and a separation member for switching the operation state, the separation

Abstract: A method for oversubscribing a host memory of a host running a virtual machine monitor (VMM), comprising, examining a virtual machine (VM) memory for a VM for metadata associated with the VM memory, the metadata maintained by a guest OS running on the VM, collecting the metadata for the VM memory, and managing the VM memory using the metadata for oversubscribing a host memory.

Abstract: A method and apparatus include a first server that communicates with a second server to cause a call back request to be communicated to an endpoint so that the endpoint can initiate a call back connection with the first server or a third server. Such a call back connection may occur near real time or in substantially real time so that updates can be supplied to an endpoint running an application supported by the server quickly and efficiently. The endpoint may register with the second server such that the second server is able to utilize notification messages for providing call back request information to the endpoint to advise the endpoint of a call back request.

Abstract: A method of conveying a location information (2) representing a physical location of a first communication device (D) from the first communication device (D) to a server (S) comprises sending a first invite message (12) of the server (S), the server (S) being triggered by a third communication device (C), to the first communication device (D) to invite the first communication device (D) to initiate a communication connection (26) to a second communication device (T), and sending an answer message (13) of the first communication device (D) in response to the first invite message (12) to the server (S), wherein the location information (2) is inserted in the answer message (13) for insertion in a second invite message (14) of the server (S) to the second communication device (T) to invite the second communication device (T) to accept the communication connection (26).

Abstract: A process for the acid-catalysed dehydration of ethanol, the process comprising the steps of distilling an ethanol feedstock (101) comprising at least one nitrogen-containing contaminant to form an overhead stream (102) and a bottom stream comprising ethanol (103), wherein the distillation has a reflux ratio of at least 20:1; and reacting the bottom stream in the presence of an acid catalyst to form a product stream comprising ethylene.

Abstract: This invention is directed in part to novel doses, dosage formulations, and routes of administration of such doses and dose formulations, said dose and dose formulations containing one or more copper chelators, for example, one or more trientine active agents, including trientine analogues, trientine salts, trientine prodrugs, and trientine derivatives, useful in the treatment of diseases, disorders and conditions, including in indications where copper may play a role.

Abstract: A simulation device for simulating the operation of a medication delivery device comprises a housing (1) and a moveable element (4) partly disposed in the housing (1). The moveable element is moveable from a first position to a second position.

Abstract: Techniques for mobile network geolocation are disclosed. In one particular exemplary embodiment, the techniques may be realized as a system for mobile network geolocation. The system may comprise one or more processors communicatively coupled to a mobile communications network. The one or more processors may be configured to determine that a mobile device is on a travel path. The one or more processors may also be configured to determine one or more candidate locations of the mobile device based on data associated with the travel path. The one or more processors may further be configured to determine at least one candidate route associated with the mobile device along the travel path comprised from one or more candidate locations.

Abstract: An analyser and related methods for characterising a sample. The analyser includes an integrated laser for emitting electromagnetic radiation in at least one beam at a sample. The electromagnetic radiation can include at least two different wavelengths. A sample detector detects affected electromagnetic radiation resulting from the emitted electromagnetic radiation affected by the sample and provides output representing the detected affected radiation. The analyser also includes a processor for characterising the sample from the detector output representing the detected affected electromagnetic radiation.

Abstract: A method of conveying a location information representing a physical location of a communication device to another communication device comprises acquiring by the communication device a first location information and a second location information, the second location information being acquired subsequently to the acquiring of the first location information and detecting by the communication device a deviation of the second location information from the first location information representing a change of the physical location of the communication device.

Abstract: A substrate with a textured surface is disclosed. The substrate may be, for example, a light emitter comprising a light guide, for example a backlight element for use in a display device, wherein a surface of the light guide, for example a glass substrate, is configured to have a textured surface with a predetermined RMS roughness and a predetermined correlation length of the texture. A plurality of light scatter supressing features can be provided on the textured surface. Textured surfaces disclosed herein may be effective to reduce electrostatic charging of the substrate surface. Methods of producing the textured surface are also disclosed.

Abstract: A gas turbine with a burner, which gas turbine has at least one fuel feed line and at least one fuel outflow line, wherein a flushing water line is connected fluidically to the fuel feed line, and wherein a leakage oil tank is connected fluidically via a drainage line to the fuel outflow line and the connection of the fuel outflow line and the drainage line is provided at a point downstream of at least one closure valve in the fuel outflow line, wherein a bypass line is connected fluidically to the fuel outflow line upstream of the closure valve, which bypass line connects the fuel outflow line fluidically to the leakage oil tank.

Abstract: A patient interface for delivery of a supply of pressurised air or breathable gas to an entrance of a patient's airways comprising: a cushion member that includes a retaining structure and a seal-forming structure permanently connected to the retaining structure; a frame member attachable to the retaining structure; and a positioning and stabilising structure attachable to the frame member.

Abstract: A method is described for communication in a tactical network. A gateway is communicatively couplable to one or more tactical nodes and to one or more other gateways. The gateway is programmed to transmit information to and/or receive information from other gateways. Information exchanged includes gateway attributes, link attributes, service availability, and/or data availability. The gateway optionally provides quality of service, distributed persistence, load balancing, and/or transformation services. Services are provided in a modular, service-oriented architecture (SOA) to accommodate the addition of services and/or applications.

Abstract: The invention relates to compounds having Formula (1): A-L-B or pharmaceutically acceptable salts thereof, wherein: A is a dicarbonyl sequestering moiety comprising a substituted aryl group or a substituted heteroaryl group; L is an optional linker moiety; and B is a mitochondrial targeting moiety. The invention also relates to pharmaceutical compositions containing such compounds and salts, and to the use of such compounds and salts for treating diabetes, preferably hyperglycemic diabetes. A mass spectrometry probe and to a method of labelling a biological molecule 1 for mass spectrometry detection are also described.

Abstract: The present invention use of to a portion of the RPS7 gene or its corresponding mRNA in a diagnostic assay for fungal and yeast species and sequences for use in such assays and methods.

Abstract: A computerized electro-mechanical drug delivery device configured to deliver at least one dose of two or more medicaments. The device comprises a control unit. An electro-mechanical drive unit is operably coupled to the control unit and a primary reservoir for a first medicament and a secondary reservoir for a fluid agent, e.g. a second medicament. An operator interface is in communication with the control unit. A single dispense assembly is configured for fluid communication with the primary and the secondary reservoir. Activation of the operator panel sets a first dose from the primary reservoir and based on the first dose and a therapeutic dose profile, the control unit is configured to determine a dose or range of the fluid agent. Alternatively, the control unit determines or calculates a dose or range of a third medicament. Further, a dispense interface for use with a drug delivery device is disclosed.

Abstract: A table for a flatbed printer comprises an upper plate (4) and a lower plate (6) separated by an intermediate layer (8). The intermediate layer is configured to provide a fluid flow path (34) that promotes a flow of fluid alternating between a position adjacent the upper plate and a position adjacent the lower plate, so as to promote heat transfer between the upper plate and the lower plate. The fluid flow path may be formed using a plurality of holes (26) in the intermediate layer. A method of manufacturing the printer table is also described.

Abstract: A nicotine delivery system is disclosed. The nicotine delivery system comprises an actuating mechanism and a housing that has a longitudinal axis and defines a chamber that is configured to receive a plunger and has an outlet for the passage of formulation out of the chamber. The actuating mechanism comprises an actuator and an actuation member. The actuator cooperates with the actuation member such that when a plunger is received in the chamber the plunger and the chamber slide relative to each other in an axial direction by a predetermined incremental distance upon each operation of the actuator to displace a predetermined volume of formulation from the chamber through said outlet.

Abstract: A method and analyser for identifying or verifying or otherwise characterising a sample comprising: using or having an electromagnetic radiation source for emitting electromagnetic radiation in at least one beam at a sample, the electromagnetic radiation comprising at least two different wavelengths, using or having a sample detector that detects affected electromagnetic radiation resulting from the emitted electromagnetic radiation affected by the sample and provides output representing the detected affected radiation, and using or having a processor for determining sample coefficients from the output, and identifying or verifying or otherwise characterising the sample using the sample coefficients and training coefficients determined from training samples, wherein the coefficients reduce sensitivity to a sample retainer variation and/or are independent of concentration.