Patents by Inventor James Smyth
James Smyth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10960393Abstract: Apparatus and methods for providing a single-use, disposable module or manifold for testing and analysis of bioprocesses, as well as a portable and compact device which can be used with the module or manifold. A module comprising a valve, a filter or guard column, an affinity column, and a flow cell is provided with several ports for receiving tubing connections for a sample and one or more solvents, as well as one or more outlet ports for connections to one or more waste reservoirs. The flow cell may use UV light to determine a protein concentration of a sample in one particular example. The module can be connected directly or indirectly to a bioreactor containing the bioprocess and material to be sampled, and can be disposed of once a production run has been completed. In addition, manifolds are provided which can be embodied as a valve assembly, and which can comprise the same components and features as the disposable module. The manifolds and modules are compact and easy to use.Type: GrantFiled: August 21, 2018Date of Patent: March 30, 2021Assignee: IDEX HEALTH AND SCIENCE LLCInventors: Victor Simonyi, Darrin Kurt Pickle, James Smyth, Craig Love
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Patent number: 10711237Abstract: Apparatus and methods for providing a single-use, disposable module or manifold for testing and analysis of bioprocesses. A module comprising a valve, a filter or guard column, an affinity column, and a flow cell is provided with several ports for receiving tubing connections for a sample and one or more solvents, as well as one or more outlet ports for connections to one or more waste reservoirs. The flow cell may use UV light to determine a protein concentration of a sample in one particular example. The module can be connected directly or indirectly to a bioreactor containing the bioprocess and material to be sampled, and can be disposed of once a production run has been completed. In addition, manifolds are provided which can be embodied as a valve assembly, and which can comprise the same components and features as the disposable module. The manifolds and modules are compact and easy to use. A portable device for use with a module is also provided.Type: GrantFiled: August 22, 2017Date of Patent: July 14, 2020Assignee: IDEX Health & Science LLCInventors: Victor Simonyi, Darrin Kurt Pickle, James Smyth, Craig Love
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Publication number: 20190060896Abstract: Apparatus and methods for providing a single-use, disposable module or manifold for testing and analysis of bioprocesses, as well as a portable and compact device which can be used with the module or manifold. A module comprising a valve, a filter or guard column, an affinity column, and a flow cell is provided with several ports for receiving tubing connections for a sample and one or more solvents, as well as one or more outlet ports for connections to one or more waste reservoirs. The flow cell may use UV light to determine a protein concentration of a sample in one particular example. The module can be connected directly or indirectly to a bioreactor containing the bioprocess and material to be sampled, and can be disposed of once a production run has been completed. In addition, manifolds are provided which can be embodied as a valve assembly, and which can comprise the same components and features as the disposable module. The manifolds and modules are compact and easy to use.Type: ApplicationFiled: August 21, 2018Publication date: February 28, 2019Inventors: Victor Simonyi, Darrin Kurt Pickle, James Smyth, Craig Love
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Publication number: 20190062688Abstract: Apparatus and methods for providing a single-use, disposable module or manifold for testing and analysis of bioprocesses. A module comprising a valve, a filter or guard column, an affinity column, and a flow cell is provided with several ports for receiving tubing connections for a sample and one or more solvents, as well as one or more outlet ports for connections to one or more waste reservoirs. The flow cell may use UV light to determine a protein concentration of a sample in one particular example. The module can be connected directly or indirectly to a bioreactor containing the bioprocess and material to be sampled, and can be disposed of once a production run has been completed. In addition, manifolds are provided which can be embodied as a valve assembly, and which can comprise the same components and features as the disposable module. The manifolds and modules are compact and easy to use. A portable device for use with a module is also provided.Type: ApplicationFiled: August 22, 2017Publication date: February 28, 2019Inventors: Victor Simonyi, Darrin Kurt Pickle, James Smyth, Craig Love
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Publication number: 20180283713Abstract: The present invention is concerned with a fluid actuated fluid extraction system, and in particular an airflow actuated gas extraction system which in use is located in an airflow such as a natural flow of wind, and which airflow actuates the system in order to extract fluid such as a gas from a remote location such as the interior of a building, the system comprising a hollow body having at least a pair of concentric annular baffles longitudinally spaced from one another to define an annular flow channel circumscribing the body between the pair of baffles into which an actuating fluid can flow from an exterior of the body, the body further having an intake to permit an exhaust fluid to enter the body longitudinally, wherein one or more of the baffles are profiled to generate a vortex within an upstream portion of the flow channel and to effect propagation of the vortex circumferentially around the channel by means of the coanda effectType: ApplicationFiled: September 9, 2016Publication date: October 4, 2018Inventors: Andrew SMYTH, David SMYTH, Gerard SMYTH, James SMYTH, Peter SMYTH
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Publication number: 20180171966Abstract: The present invention is concerned with a wind turbine which is designed to start rotating in lower wind speeds than is conventionally possible, the wind turbine comprising a power take off shaft on which a first rotor is mounted, the first rotor having a first diameter, and on which shaft a rotatable augmentor in the form of a second rotor is mounted coaxially of the first rotor, the second rotor having a second diameter smaller than the first diameter.Type: ApplicationFiled: June 20, 2016Publication date: June 21, 2018Inventors: James SMYTH, Peter SMYTH, David SMYTH, Gerard SMYTH, Andrew SMYTH
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Patent number: 9753950Abstract: A computer system comprises a processor capable of executing processor executable code operably coupled with a non-transitory computer medium storing processor executable code, which when executed by the processor causes the processor to: (a) receive a first signal over a computer network, the first signal indicative of a request for information about a target structure from a user; (b) in response to receiving the first signal, access a database including information about the target structure; and (c) transmit a second signal over the computer network indicative of a virtual property report for the target structure including at least one image of the target structure. The virtual property report may include information about a facet of the target structure facing a street, location of a main entrance of the target structure, location of a secondary entrance of the target structure, location of vehicle access to the target structure.Type: GrantFiled: March 15, 2013Date of Patent: September 5, 2017Assignee: Pictometry International Corp.Inventors: Stephen L. Schultz, David Arthur Kennedy, James Smyth
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Patent number: 9739383Abstract: A multi-path selector valve used in liquid chromatography and other analytical methods for directing fluid along alternate paths of a flowstream. The selector valve has a stator and a rotor. The dynamic face of the stator has a plurality of openings arranged along an inner ring, a plurality of openings arranged along an outer ring, and an annular collection groove formed in the dynamic face. The inner ring, outer ring, and annular collection groove are concentric circles. The rotor's dynamic face is configured to mate with the rear face of the stator, and has two fluid flow paths. One fluid flow path has one end at a rotational center of the rotor and another end of the fluid flow path is configured to be aligned with a stator opening along the inner ring. The second fluid flow path has one end that is configured to be aligned with the annular collection groove and another end that is configured to be aligned with a stator opening along the outer ring.Type: GrantFiled: July 28, 2015Date of Patent: August 22, 2017Assignee: IDEX Health & Science LLCInventors: Jon A. Nichols, James Smyth
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Publication number: 20170175704Abstract: The present invention provides a pressure controlled wind turbine enhancement system and a method of enhancing the airflow past a wind turbine, the enhancement system including a two part conical nozzle to be located upwind or upstream of a turbine in order to augment the natural flow of air past blades of the turbine in a manner which produces increased power output from the turbine.Type: ApplicationFiled: March 1, 2017Publication date: June 22, 2017Inventors: James SMYTH, Peter SMYTH, David SMYTH, Gerard SMYTH, Andrew SMYTH
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Publication number: 20160033049Abstract: A multi-path selector valve used in liquid chromatography and other analytical methods for directing fluid along alternate paths of a flowstream. The selector valve has a stator and a rotor. The dynamic face of the stator has a plurality of openings arranged along an inner ring, a plurality of openings arranged along an outer ring, and an annular collection groove formed in the dynamic face. The inner ring, outer ring, and annular collection groove are concentric circles. The rotor's dynamic face is configured to mate with the rear face of the stator, and has two fluid flow paths. One fluid flow path has one end at a rotational center of the rotor and another end of the fluid flow path is configured to be aligned with a stator opening along the inner ring. The second fluid flow path has one end that is configured to be aligned with the annular collection groove and another end that is configured to be aligned with a stator opening along the outer ring.Type: ApplicationFiled: July 28, 2015Publication date: February 4, 2016Inventors: Jon A. NICHOLS, James SMYTH
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Patent number: 9150924Abstract: The present disclosure provides methods involving use of BIN1 expression levels, in heart tissue, in evaluating the risk of a poor outcome in a patient diagnosed with congestive heart failure. The methods finds use in evaluating patients who are heart transplant candidates as well as in assessing therapy options and efficacy of treatment in congestive heart failure patients.Type: GrantFiled: February 10, 2014Date of Patent: October 6, 2015Assignee: The Regents of the University of CaliforniaInventors: Robin Shaw, Ting-Ting Hong, James Smyth
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Publication number: 20140321974Abstract: A wind turbine system having a street light having an upright support or post on which is mounted a canopy housing any suitable lighting gear, and a wind turbine mounted above the canopy and operable to generate electrical energy with which to power the light, the canopy being adapted to augment the flow of air through the wind turbine.Type: ApplicationFiled: May 7, 2013Publication date: October 30, 2014Applicant: NEW WORLD ENERGY ENTERPRISES LTDInventors: James SMYTH, Peter SMYTH, David SMYTH, Gerard SMYTH, Andrew SMYTH
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Publication number: 20140302502Abstract: The present disclosure provides methods involving use of BIN1 expression levels, in heart tissue, in evaluating the risk of a poor outcome in a patient diagnosed with congestive heart failure. The methods finds use in evaluating patients who are heart transplant candidates as well as in assessing therapy options and efficacy of treatment in congestive heart failure patients.Type: ApplicationFiled: February 10, 2014Publication date: October 9, 2014Applicant: The Regents of the University of CaliforniaInventors: Robin Shaw, Ting-Ting Hong, James Smyth
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Publication number: 20140280269Abstract: A computer system comprises a processor capable of executing processor executable code operably coupled with a non-transitory computer medium storing processor executable code, which when executed by the processor causes the processor to: (a) receive a first signal over a computer network, the first signal indicative of a request for information about a target structure from a user; (b) in response to receiving the first signal, access a database including information about the target structure; and (c) transmit a second signal over the computer network indicative of a virtual property report for the target structure including at least one image of the target structure. The virtual property report may include information about a facet of the target structure facing a street, location of a main entrance of the target structure, location of a secondary entrance of the target structure, location of vehicle access to the target structure.Type: ApplicationFiled: March 15, 2013Publication date: September 18, 2014Inventors: Stephen L. Schultz, David Arthur Kennedy, James Smyth
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Publication number: 20140127030Abstract: A wind turbine blade system having a main blade having a root and a tip, and at least one secondary blade secured to or formed integrally with the main blade about the tip, the at least one secondary blade being shaped and dimensioned to form, when the main blade is rotated, a shroud circumscribing a swept area of the main blade in order to improve the airflow past the main blade during operation of the wind turbine.Type: ApplicationFiled: October 22, 2013Publication date: May 8, 2014Inventors: James SMYTH, Gerard SMYTH, Andrew SMYTH, David SMYTH, Peter SMYTH
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Publication number: 20140044552Abstract: A blade for use in rotary machines such as a wind turbine blade has a plurality of dimples distributed over an area of a low pressure or suction surface of the blade which preferably extends from immediately adjacent to a leading edge of the blade at least partially towards a rear or trailing edge of the blade.Type: ApplicationFiled: May 20, 2013Publication date: February 13, 2014Applicant: NEW WORLD ENERGY ENTERPRISES LTDInventors: James SMYTH, Peter SMYTH, David SMYTH, Gerard SMYTH, Andrew SMYTH
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Publication number: 20130340419Abstract: An air handling system comprising an air guide in the form of a convergent divergent shroud and/or diffuser defining a path along which air can flow, such as to generate one or more regions of reduced pressure and/or increased mass flow rate of air within the guide in response to the passage of air through the guide, and a manifold extending from the guide and having an inlet and an exhaust, the exhaust being in fluid communication with the one or more regions of reduced pressure and/or increased mass flow rate and the inlet being in fluid communication with an interior of an air handling unit such as a condenser or air conditioning unit.Type: ApplicationFiled: March 27, 2013Publication date: December 26, 2013Applicant: c/o NEW WORLD ENERGY ENTERPRISES LTDInventors: James SMYTH, Peter SMYTH, David SMYTH, Gerard SMYTH, Andrew SMYTH
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Publication number: 20120141266Abstract: The present invention provides a pressure controlled wind turbine enhancement system which includes a two part conical shroud to be located directly upwind of a turbine in order to augment the natural flow of air past blades of the turbine in a manner which produces increased power output from the turbine.Type: ApplicationFiled: June 18, 2010Publication date: June 7, 2012Applicant: NEW WORLD ENERGY ENTERPRISES LIMITEDInventors: James Smyth, Peter Smyth, David Smyth, Gerard Smyth, Andrew Smyth
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Publication number: 20120094300Abstract: The present disclosure provides methods involving use of BIN1 expression levels, in heart tissue, in evaluating the risk of a poor outcome in a patient diagnosed with congestive heart failure. The methods finds use in evaluating patients who are heart transplant candidates as well as in assessing therapy options and efficacy of treatment in congestive heart failure patients.Type: ApplicationFiled: April 23, 2010Publication date: April 19, 2012Inventors: Robin Shaw, Ting-Ting Hong, James Smyth
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Publication number: 20110048019Abstract: The present invention is concerned with a system and method for enhancing the performance of a wind turbine, which involves injecting air from an array of nozzles into the airflow upstream of the turbine in order to reduce the turbulence and/or increase the velocity and/or control the pressure of the airflow, thereby improving the performance of the turbine.Type: ApplicationFiled: February 23, 2009Publication date: March 3, 2011Inventors: David Smyth, James Smyth, Peter Smyth, Gerard Smyth, Andrew Smyth