Patents by Inventor James Stattel

James Stattel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FC RECEPTOR BINDING PROTEINS
    Publication number: 20140248287
    Abstract: This disclosure provides, inter alia, proteins that bind to FcRn, e.g., immunoglobulins that inhibit FcRn with high affinity and selectivity. The FcRn-binding proteins can be used to treat a variety of disorders including autoimmune disorders.
    Type: Application
    Filed: January 30, 2014
    Publication date: September 4, 2014
    Applicants: SYNTONIX PHARMACEUTICALS, INC., DYAX CORP.
    Inventors: Christopher TenHoor, Arumugam Muruganandam, Robert Charles Ladner, Clive Wood, Alan J. Bitonti, James Stattel, Kevin McDonnell, Liming Liu, Jennifer Dumont, Aaron K. Sato, Malini Viswanathan
  • Fc receptor binding proteins
    Patent number: 8815246
    Abstract: This disclosure provides, inter alia, proteins that bind to FcRn, e.g., immunoglobulins that inhibit FcRn with high affinity and selectivity. The FcRn-binding proteins can be used to treat a variety of disorders including autoimmune disorders.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: August 26, 2014
    Assignees: Dyax Corp., Syntonix Pharmaceuticals, Inc.
    Inventors: Christopher TenHoor, Arumugam Muruganandam, Robert Charles Ladner, Clive Wood, Alan J. Bitonti, James Stattel, Kevin McDonnell, Liming Liu, Jennifer Dumont, Aaron K. Sato, Malini Viswanathan
  • FC RECEPTOR BINDING PROTEINS
    Publication number: 20130078262
    Abstract: This disclosure provides, inter alia, proteins that bind to FcRn, e.g., immunoglobulins that inhibit FcRn with high affinity and selectivity. The FcRn-binding proteins can be used to treat a variety of disorders including autoimmune disorders.
    Type: Application
    Filed: September 14, 2012
    Publication date: March 28, 2013
    Applicant: Dyax Corp.
    Inventors: Christopher TenHoor, Arumugam Muruganandam, Robert Charles Ladner, Clive Wood, Alan J. Bitonti, James Stattel, Kevin McDonnell, Liming Liu, Jennifer Dumont, Aaron Sato, Malini Viswanathan
  • FC RECEPTOR BINDING PROTEINS
    Publication number: 20130045218
    Abstract: This disclosure provides, inter alia, proteins that bind to FcRn, e.g., immunoglobulins that inhibit FcRn with high affinity and selectivity. The FcRn-binding proteins can be used to treat a variety of disorders including autoimmune disorders.
    Type: Application
    Filed: August 13, 2012
    Publication date: February 21, 2013
    Applicants: Syntonix Pharmaceuticals, Inc., Dyax Corp.
    Inventors: Christopher TenHoor, Arumugam Muruganandam, Robert Charles Ladner, Clive Wood, Alan J. Bitonti, James Stattel, Kevin McDonnell, Liming Liu, Jennifer Dumont, Aaron Sato, Malini Viswanathan
  • Fc receptor binding proteins
    Patent number: 8273351
    Abstract: This disclosure provides, inter alia, proteins that bind to FcRn, e.g., immunoglobulins that inhibit FcRn with high affinity and selectivity. The FcRn-binding proteins can be used to treat a variety of disorders including autoimmune disorders.
    Type: Grant
    Filed: April 24, 2009
    Date of Patent: September 25, 2012
    Assignees: Dyax Corp., Syntonix Pharmaceuticals, Inc.
    Inventors: Christopher TenHoor, Arumugam Muruganandam, Robert Charles Ladner, Clive Wood, Alan J. Bitonti, James Stattel, Kevin McDonnell, Liming Liu, Jennifer Dumont, Aaron Sato
  • Immunoglobulin Chimeric Monomer-Dimer Hybrids
    Publication number: 20110182919
    Abstract: The invention relates to a chimeric monomer-dimer hybrid protein wherein said protein comprises a first and a second polypeptide chain, said first polypeptide chain comprising at least a portion of an immunoglobulin constant region and a biologically active molecule, and said second polypeptide chain comprising at least a portion of an immunoglobulin constant region without the biologically active molecule of the first chain. The invention also relates to methods of using and methods of making the chimeric monomer-dimer hybrid protein of the invention.
    Type: Application
    Filed: November 23, 2010
    Publication date: July 28, 2011
    Inventors: Robert T. PETERS, Adam R. Mezo, Daniel S. Rivera, Alan J. Bitonti, James Stattel, Susan C. Low
  • FC RECEPTOR BINDING PROTEINS
    Publication number: 20090324614
    Abstract: This disclosure provides, inter alia, proteins that bind to FcRn, e.g., immunoglobulins that inhibit FcRn with high affinity and selectivity. The FcRn-binding proteins can be used to treat a variety of disorders including autoimmune disorders.
    Type: Application
    Filed: April 24, 2009
    Publication date: December 31, 2009
    Applicants: Dyax Corp., Syntonix Pharmaceuticals, Inc.
    Inventors: Christopher TenHoor, Arumugam Muruganandam, Robert Charles Ladner, Clive Wood, Alan J. Bitonti, James Stattel, Kevin McDonnell, Liming Liu, Jennifer Dumont, Aaron Sato
  • Immunoglobulin chimeric monomer-dimer hybrids
    Patent number: 7348004
    Abstract: The invention relates to a chimeric monomer-dimer hybrid protein wherein said protein comprises a first and a second polypeptide chain, said first polypeptide chain comprising at least a portion of an immunoglobulin constant region and a biologically active molecule, and said second polypeptide chain comprising at least a portion of an immunoglobulin constant region without the biologically active molecule of the first chain. The invention also relates to methods of using and methods of making the chimeric monomer-dimer hybrid protein of the invention.
    Type: Grant
    Filed: January 5, 2005
    Date of Patent: March 25, 2008
    Assignee: Syntonix Pharmaceuticals, Inc.
    Inventors: Robert T. Peters, Adam R. Mezo, Daniel S. Rivera, Alan J. Bitonti, Susan C. Low, James Stattel
  • Fc chimeric proteins with anti-HIV drugs
    Publication number: 20050281829
    Abstract: The invention relates to anti viral agents comprised of viral fusion inhibitors and at least a portion of an immunoglobulin constant region. The invention further relates to anti viral agents comprised HIV viral fusion inhibitors and an Fc fragment of an immunoglobulin. The invention also relates to methods of treating a viral infection, including HIV infection.
    Type: Application
    Filed: May 6, 2004
    Publication date: December 22, 2005
    Inventors: Cristina Hehir, Adam Mezo, Robert Peters, James Stattel, Vito Palombella, Alan Bitonti
  • Immunoglobulin chimeric monomer-dimer hybrids
    Publication number: 20050260194
    Abstract: The invention relates to a chimeric monomer-dimer hybrid protein wherein said protein comprises a first and a second polypeptide chain, said first polypeptide chain comprising at least a portion of an immunoglobulin constant region and a biologically active molecule, and said second polypeptide chain comprising at least a portion of an immunoglobulin constant region without the biologically active molecule of the first chain. The invention also relates to methods of using and methods of making the chimeric monomer-dimer hybrid protein of the invention.
    Type: Application
    Filed: January 5, 2005
    Publication date: November 24, 2005
    Inventors: Robert Peters, Adam Mezo, Daniel Rivera, Alan Bitonti, Susan Low, James Stattel
  • INHIBITION OF DRUG BINDING TO SERUM ALBUMIN
    Publication number: 20050037947
    Abstract: The invention relates to improved therapeutics for treating diseases or conditions that provide greater bioavailabilty and more predictable dosing. The invention relates to a chimeric protein comprised of a biologically active molecule linked to an Fc fragment of an immunoglobulin, wherein the chimeric protein binds less serum albumin compared to the same biologically active molecule of the chimeric protein not linked to an Fc fragment of an immunoglobulin.
    Type: Application
    Filed: May 6, 2004
    Publication date: February 17, 2005
    Inventors: Alan Bitonti, Vito Palombella, James Stattel, Robert Peters
  • Immunoglobulin chimeric monomer-dimer hybrids
    Publication number: 20050032174
    Abstract: The invention relates to a chimeric monomer-dimer hybrid protein wherein said protein comprises a first and a second polypeptide chain, said first polypeptide chain comprising at least a portion of an immunoglobulin constant region and a biologically active molecule, and said second polypeptide chain comprising at least a portion of an immunoglobulin constant region without the biologically active molecule of the first chain. The invention also relates to methods of using and methods of making the chimeric monomer-dimer hybrid protein of the invention.
    Type: Application
    Filed: May 6, 2004
    Publication date: February 10, 2005
    Inventors: Robert Peters, Adam Mezo, Daniel Rivera, Alan Bitonti, James Stattel, Susan Low