Abstract: The present disclosure provides one filter with multiple standing compression seals that work together to seal against the mating filter housing assembly. The first compression bead design enables the second bead to seal against the Housing surface for maximum sealing performance for preventing unfiltered fluid from passing through a filter housing assembly.

Abstract: A testing system and test cartridge for analyzing a sample of water from a water source for specific analyte levels. The test cartridge including a membrane filter that captures a target analyte while allowing a labelled conjugate to permeate through the membrane. The conjugate includes an analyte-specific labelled binding reagent to bind with the target analyte for optical detection. The direct membrane interrogation (i.e., on-filter detection), determines analyte levels without elution of the analyte from a filter thereby improving analyte recovering and assay sensitivity.

Abstract: The present disclosure provides one filter with multiple standing compression seals that work together to seal against the mating filter housing assembly. The first compression bead design enables the second bead to seal against the Housing surface for maximum sealing performance for preventing unfiltered fluid from passing through a filter housing assembly.

Abstract: Compositions containing bacteriophages and methods of using bacteriophages in microorganism detection assays and microbial growth and plating media are disclosed. The lytic ability of these phages to control the growth of non-target populations provides superior sensitivity and specificity to detection assays and reduces false negative and false positive results. The removal of contaminating bacteria reduces the microbial competition for nutrients in the growth media thereby increasing the efficiency and productivity of the culture. The phage treatment of the sample increases the proportion of target microorganisms in the sample over contaminating bacteria thereby requiring less time for enrichment to obtain a significant signal improving overall signal to noise ratio in assays and providing for higher yield of end product in microbiological production systems.

Abstract: Haptens, ligands (including antibodies), immunoassays, and test kits for detecting tobacco-specific nitrosamines (TSNAs) in samples such as tobacco products are provided. The hapten is a molecule that contains one or more structural characteristics of one or more TSNAs, and is bound to an immunogenic carrier. An antibody specific for one or more TSNAs is produced by immunizing an animal with the hapten bound to the carrier. Immunoassays and test kits using those antibodies are also provided.