Abstract: An expansion anchor having an anchor bolt, an expansion sleeve surrounding the anchor bolt, and an expansion body located in a front region of the anchor bolt, wherein the expansion body has a converging zone for expanding the expansion sleeve. The expansion body has at least one expansion sleeve abutment wall facing the expansion sleeve. The invention also relates to a method for using such an expansion anchor.

Abstract: The disclosure provides, e.g., compositions, systems, and methods for targeting, editing, modifying, or manipulating a host cell's genome at one or more locations in a DNA sequence in a cell, tissue, or subject. Gene modifying systems for treating cystic fibrosis, e.g., in subjects having a mutation resulting in F508del, are described.

Abstract: The disclosure provides, e.g., compositions, systems, and methods for targeting, editing, modifying, or manipulating a host cell's genome at one or more locations in a DNA sequence in a cell, tissue, or subject. Gene modifying systems for treating phenylketonuria (PKU) are described.

Abstract: Methods and compositions for modulating a target genome are disclosed.

Abstract: The disclosure provides, e.g., compositions, systems, and methods for targeting, editing, modifying, or manipulating a host cell's genome at one or more locations in a DNA sequence in a cell, tissue, or subject. Gene modifying systems for treating alpha-1 antitrypsin deficiency (AATD) are described.

Abstract: Methods and compositions for modulating a target genome are disclosed.

Abstract: A method of providing flight information to a receiving node in data communication with a server. A server receives from a sending node data (1) permitting identification of a flight of interest and (2) permitting identification of the receiving node. The data received at the server causes delivery to the receiving node of a message that includes a logon key that grants access by the receiving node to a data source that provides real-time dynamic information as to position of the flight of interest.

Abstract: A system and method for providing to a user a candidate list of flight plans that specify one or more planned routes of flight from one location to another location, such routes satisfying certain criteria. These criteria include ranking the candidate list of flight plans according to the probability that the flight plan may be allowed or cleared by a controlling authority based on historic cleared flight plans; further qualifying this list by considering only candidate flight plans cleared during specified weather conditions; or specified time periods; or requested speed and/or altitude and/or aircraft type of flight parameters. Various embodiments include providing the candidate list of flight plans to the user by means of a communication system that is composed of a combination of a wide-area network, a wireless network or the internet. Additionally, an embodiment includes providing the flight plan data to a global positioning system (GPS) of a user.

Abstract: A method is provided for characterizing traffic behavior at an airport. Scheduled and real-time flight information for the airport is obtained and used to determine, over a selected interval of time, flight delay information. The flight delay information is used to characterize an extent of delay for the airport. Various embodiments characterize traffic behavior at a plurality of distinct airports and traffic behavior of a selected airline, both at an airport and at distinct airports.

Abstract: A computer-based method of displaying real time flight information for aircraft. includes retrieving data previously stored for which there is real time flight information and causing display, on a screen of a client computing device, automatically and repetitively of a plurality of views of a geographic map. Such views collectively display all viewable flights in a pre-specified category. The embodiment additionally includes causing display simultaneously on the screen of the client computing device, with the geographic map, of a list of flights in the pre-specified category. The list scrolls automatically at least to the extent necessary to cause repetitive display of the entire list. Additionally, contents of the list are coordinated with each of the views.

Abstract: A method is provided for characterizing traffic behavior at an airport. Scheduled and real-time flight information for the airport is obtained and used to determine, over a selected interval of time, flight delay information. The flight delay information is used to characterize an extent of delay for the airport. Various embodiments characterize traffic behavior at a plurality of distinct airports and traffic behavior of a selected airline, both at an airport and at distinct airports.

Abstract: A system and method for providing to a user a candidate list of flight plans that specify one or more planned routes of flight from one location to another location, such routes satisfying certain criteria. These criteria include ranking the candidate list of flight plans according to the probability that the flight plan may be allowed or cleared by a controlling authority based on historic cleared flight plans; further qualifying this list by considering only candidate flight plans cleared during specified weather conditions; or specified time periods; or requested speed and/or altitude and/or aircraft type of flight parameters. Various embodiments include providing the candidate list of flight plans to the user by means of a communication system that is composed of a combination of a wide-area network, a wireless network or the internet. Additionally, an embodiment includes providing the flight plan data to a global positioning system (GPS) of a user.

Abstract: A method is provided for characterizing traffic behavior at an airport. Scheduled and real-time flight information for the airport is obtained and used to determine, over a selected interval of time, flight delay information. The flight delay information is used to characterize an extent of delay for the airport. Various embodiments characterize traffic behavior at a plurality of distinct airports and traffic behavior of a selected airline, both at an airport and at distinct airports.

Abstract: A method and system estimate, in real time, the amount of any delay in departure of an aircraft flight from an airport. Various embodiments include receiving in a first computer process a conditions input that includes at least one member of a set including departure airport conditions, arrival airport conditions, and fleet conditions; and estimating in a second computer process the amount of delay based on the conditions input. User interfaces and data structures are also provided.

Abstract: A method is provided for characterizing traffic behavior at an airport. Scheduled and real-time flight information for the airport is obtained and used to determine, over a selected interval of time, flight delay information. The flight delay information is used to characterize an extent of delay for the airport. Various embodiments characterize traffic behavior at a plurality of distinct airports and traffic behavior of a selected airline, both at an airport and at distinct airports.

Abstract: A method and system estimate, in real time, the amount of any delay in departure of an aircraft flight from an airport. Various embodiments include receiving in a first computer process a conditions input that includes at least one member of a set including departure airport conditions, arrival airport conditions, and fleet conditions; and estimating in a second computer process the amount of delay based on the conditions input. User interfaces and data structures are also provided.

Abstract: A method and system estimate, in real time, the amount of any delay in departure of an aircraft flight from an airport. Various embodiments include receiving in a first computer process a conditions input that includes at least one member of a set including departure airport conditions, arrival airport conditions, and fleet conditions; and estimating in a second computer process the amount of delay based on the conditions input. User interfaces and data structures are also provided.

Abstract: A method and system estimate, in real time, the amount of any delay in departure of an aircraft flight from an airport. Various embodiments include receiving in a first computer process a conditions input that includes at least one member of a set including departure airport conditions, arrival airport conditions, and fleet conditions; and estimating in a second computer process the amount of delay based on the conditions input. User interfaces and data structures are also provided.

Abstract: A method and system estimate, in real time, the amount of any delay in departure of an aircraft flight from an airport. Various embodiments include receiving in a first computer process a conditions input that includes at least one member of a set including departure airport conditions, arrival airport conditions, and fleet conditions; and estimating in a second computer process the amount of delay based on the conditions input. User interfaces and data structures are also provided.