Abstract: Methods for classifying and for evaluating the prognosis of a subject having breast cancer are provided. The methods include prediction of breast cancer subtype using a supervised algorithm trained to stratify subjects on the basis of breast cancer intrinsic subtype. The prediction model is based on the gene expression profile of the intrinsic genes listed in Table 1. This prediction model can be used to accurately predict the intrinsic subtype of a subject diagnosed with or suspected of having breast cancer. Further provided are compositions and methods for predicting outcome or response to therapy of a subject diagnosed with or suspected of having breast cancer. These methods are useful for guiding or determining treatment options for a subject afflicted with breast cancer.

Abstract: A trailer reversing assist system for controlling reversing operations of a vehicle and trailer connected to the vehicle includes a module that detects an angle of the trailer relative to the vehicle, and outputs a trailer angle signal corresponding to the detected angle. The system also includes a human machine interface (HMI) device that provides an output signal based upon an input of the user, where the generated output signal includes information regarding magnitude and direction of a desired change to the angle. The system calculates a trailer trajectory that positions the trailer at a target location or calculates a trailer trajectory correction, wherein the calculation is performed using the output signal as corresponding to a change relative to the detected angle, and the detected angle corresponds to the trailer angle signal generated at the time of operation of the HMI device by the user.

Abstract: Methods and compositions for treating a urothelial and/or a micropapillary carcinoma, such as a micropapillary urothelial carcinoma are disclosed.

Abstract: A method for generating a rear-view display of a vehicle coupled to a trailer. The method includes detecting that the vehicle is in a reverse gear or is turning and determining a trailer angle of the vehicle. The method further includes generating a blended image based on the trailer angle, a first video image from a rear-facing vehicle camera positioned on the vehicle, the first video image including a first region of interest including a trailer coupled to the vehicle, and a second video image from a rear-facing trailer camera positioned on the trailer, the second video image including a second region of interest of a rearview of the trailer, the blended image including an overlay of at least a portion of the second video image over the trailer in the first video image and displaying the blended image on the display.

Abstract: A method of analyzing a sample imaged by electron backscatter diffraction. The method comprises identifying a plurality of Kikuchi bands in an electron backscatter diffraction image of a position on the sample. The method further comprises forming, for each identified Kikuchi band, a respective vector representation of said Kikuchi band based at least in part on an estimate of the position on the sample. A configuration of the sample is determined by identifying a particular set of expected vector representations from a plurality of sets of expected vector representations as matching the vector representations of the plurality of identified Kikuchi bands.

Abstract: Methods of treating a head and neck cancer are disclosed.

Abstract: Novel mutant ESR1 molecules and uses are disclosed.

Abstract: Methods and systems for aligning a vehicle with a trailer. One system includes an image sensor configured to collect a plurality of images. The system also includes an electronic processor configured to receive the plurality of images from the image sensor. The electronic processor is also configured to determine a three-dimensional model of an area surrounding the vehicle using the plurality of images. The electronic processor is also configured to control the vehicle to automatically perform a vehicle maneuver to align the vehicle with the trailer based on the three-dimensional model of the area surrounding the vehicle. The electronic processor is also configured to determine when the vehicle is aligned with the trailer and stop the vehicle from automatically performing the vehicle maneuver when the vehicle is aligned with the trailer.

Abstract: Systems, devices, and methods are disclosed for wireless communication of analyte data. In this regard, in embodiments, a mobile includes a transceiver configured to transmit and receive wireless signals. The mobile device includes circuitry operatively coupled to the transceiver. The mobile device also includes a non-transitory computer-readable medium operatively coupled to the circuitry and storing instructions that, when executed, cause the mobile device to perform a number of operations. One such operation is to obtain a derivative of a first signal received via a first link. Another such operation is to obtain a derivative of a second signal received via a second link; and. Yet another such operation is to generate a selection for connection to an analyte sensor system, based on a comparison of the derivative of the first signal and the derivative of the second signal.

Abstract: The disclosure herein describes management of transaction blocking schemes via a user interface. A transaction blocking scheme is receiving via the user interface from a user, including transaction blocking rules. The transaction blocking rules are applied to transaction data associated with the user. Transaction blocking scheme performance data is generated based on the application of the transaction blocking rules to the transaction data, including a quantity of transactions of the transaction data that are blocked by the transaction blocking rules. A visualization of the transaction blocking scheme performance data is displayed via the user interface and the user is prompted to provide a response based on the displayed visualization. Based on the response to the prompt, the transaction blocking scheme is activated for application to incoming transactions, whereby the transaction blocking rules are applied to incoming transactions to determine whether to block the incoming transactions.

Abstract: In various embodiments a capture surface for capturing high velocity and hypervelocity dust and ice particles is provided. In certain embodiments the capture surface is comprised of a soft metal that is chosen to optimize particle capture efficiency, to minimize thermal degradation of chemicals and biochemical in the particles, and to present the captured particles to an analyzer for chemical and biochemical analysis of the particles and their contents. In various embodiments capture chambers comprising one or more such capture surfaces are provided as well as methods of use thereof.

Abstract: Techniques disclosed herein are directed to detect the presence of false, incorrect, or spoofed Global Navigation Satellite Systems (GNSS) signals. Embodiments may comprise receiving, at a mobile device, a global navigation satellite system (GNSS) signal via a GNSS antenna of the mobile device; determining first movement data based on the GNSS signal; determining second movement data based on data from one or more motion sensors of the mobile device, wherein the first movement data and the second movement data each comprise respective movement-related information regarding the mobile device during a time period; and providing an indication that GNSS error is occurring based on a determination that a difference between first movement data and the second movement data exceeds a threshold.

Abstract: Detecting a damage angle between a vehicle and a trailer. One example system includes an electronic controller and a rear-view camera configured to obtain video of the trailer. The electronic controller is configured to receive the video of the trailer from the rear-view camera and determine a damage point based upon the video of the trailer. The electronic controller is further configured to determine a change in a rotation angle of the trailer and determine a changed location of the damage point of the trailer based upon the change in the rotation angle of the trailer. The electronic controller is also configured to determine a damage angle based upon the changed location of the damage point relative to the vehicle and determine at least one maneuver to avoid collision between the damage point and the vehicle based upon the damage angle.

Abstract: A method and system for generating a composite video for display in a vehicle. A plurality of video streams are generated from a plurality of video cameras configured to be positioned on the vehicle. The video streams are transformed by an electronic processor to create a virtual camera viewpoint. The transformed video streams are combined to generate a composite video including a portion of a first image that is generated from a first one of the video cameras. The electronic processor detects an object external to the vehicle and determines whether the object at least partially obscures the portion of the first image. When the object at least partially obscures the portion of the first image, the electronic processor supplements the portion of the first image with a portion of a second image that is generated by a second one of the video cameras.

Abstract: Various embodiments provide interfaces to access genomic testing information and incorporate it into daily physician practice. According to one aspect, a graph-based data model is used that may be used to organizes and revise precision medicine knowledge. In one example structure, gene states are abstracted into alteration groups, where alteration groups are built using reverse engineering actionable information and storing that information within the graph-based data structure. Volumes of genomic alterations and associated information (e.g., journal articles, clinical trial information, therapies, etc.) are analyzed and synthesized into actionable information items viewable on an alteration system in a graph-based data format. According to one embodiment, the system can be configured to focus practitioners on discrete portions of the alteration information on which they can act.

Abstract: A system and method for encapsulating commercially significant attributes of a hydrocarbon product into a single digital signature are presented. The digital signature may be generated from a physical product sample using optical techniques such as NIR spectroscopy. Digital signatures may be expressed in the form of composition, principle components derived from the spectra, or other properties derived from the original spectra which characterize, and help visualize, the variation present within the signals. Other physical property measurements and contaminant measurements may also be included in the digital signature and may be derived from the same measurement device or separate measurement devices whose output is integrated into a single digital signature. Embodiments of the invention may be used to confirm the identity of a hydrocarbon product, or to verify the composition of a hydrocarbon product.

Abstract: Techniques for modifying a garment based on gestures are presented herein. An access module can access a first set of sensor data from a first sensor, and a second set of sensor data from a second sensor. A garment simulation module can generate a three-dimensional (3D) garment model of a garment available for sale draped on an avatar based on the first set of sensor data and the second set of sensor data. A display module can cause a presentation, on a display of a device, of the 3D garment model draped on the avatar. Additionally, the garment simulation module can determine a modification gesture associated with the 3D garment model draped on the avatar based on the first set of sensor data and the second set of sensor data. Furthermore, the garment simulation module can modify the 3D garment model based on the determined modification gesture.

Abstract: A method of analyzing a tumor sample comprising: (a) acquiring a library comprising a plurality of tumor members from a tumor sample; (b) contacting the library with a bait set to provide selected members; (c) acquiring a read for a subgenomic interval from a tumor member from said library; (d) aligning said read; and (e) assigning a nucleotide value (e.g., calling a mutation) from said read for the preselected nucleotide position, thereby analyzing said tumor sample.

Abstract: A heat exchange ribbon includes a base portion to be attached to a spacer to be mounted to a circuit board, a tail portion substantially parallel to the base portion, and a leg connecting the tail portion to the base portion. A height of the leg extends in the same direction as a height of the base portion and the tail portion so as to create an opening at least partially surrounded by the base portion, the leg, and the tail portion. The base portion, the tail portion, and the leg portion have a one-piece construction. The leg extends below a lower edge of the base portion such that at least a portion of the tail portion is located below a lower edge of the base portion, and at least a portion of an inner surface of the tail portion does not oppose the outer surface of the base portion.

Abstract: Methods and compositions for treating cholangiocarcinoma.