Abstract: Provided are 5-membered heteroaryl-containing aminopyridine compounds and pharmaceutically acceptable compositions thereof which exhibit inhibition activity against certain mutated forms of EGFR.

Abstract: The invention is directed to a method of treating attention-deficit/hyperactivity disorder (ADHD) in a subject, comprising administering a therapeutically effective amount of a carbamoyl compound, or pharmaceutically acceptable salt thereof.

Abstract: A mask apparatus for a respiratory treatment can permit delivery of breathable gas to a user. In one example, the mask may employ a frame and cushion to form a seal for both mouth and nose. The frame may be adapted for coupling with a respiratory treatment apparatus so as to permit communication of a pressurized gas from the respiratory treatment apparatus. The cushion, which may be foam, may have a substantially under the nose configuration or over the nose configuration. The mask may have a common plenum chamber for both nose and mouth. The cushion may further define a centrally open lip superior region. The cushion may be adapted to couple with the frame directly or to the frame in conjunction with a cushion support clip. Various features of the cushion may further promote sealing and comfort for the under the nose design.

Abstract: A mask apparatus for a respiratory treatment can permit delivery of breathable gas to a user. In one example, the mask may employ a frame and cushion to form a seal for both mouth and nose. The frame may be adapted for coupling with a respiratory treatment apparatus so as to permit communication of a pressurized gas from the respiratory treatment apparatus. The cushion, which may be foam, may have a substantially under the nose configuration or over the nose configuration. The mask may have a common plenum chamber for both nose and mouth. The cushion may further define a centrally open lip superior region. The cushion may be adapted to couple with the frame directly or to the frame in conjunction with a cushion support clip. Various features of the cushion may further promote sealing and comfort for the under the nose design.

Abstract: A system and method to collect collecting data for customizing a facial interfacing structure for a head-mounted display interface for virtual reality or augmented reality systems. Facial image data is correlated to a user such as by scanning the face of the user. Facial feature data related to the facial interfacing structure is determined from the facial image data. Dimensions of the facial interfacing structure are determined from the facial feature data. A design of a customized facial interfacing structure including the determined dimensions is stored to produce the customized facial interfacing structure.

Abstract: A method includes receiving electronically data associated with physical or psychological factors of a user, the data being collected from (a) a plurality of smart home devices, (b) a plurality of mobile devices, or (c) both. The physical or psychological factors are based on at least one physical activity of the user. The method further includes identifying, based on the data, an effect on sleep quality of the user, based on which a remedial action is determined for improving sleep quality of the user. The method also includes causing the remedial action to be communicated in electronic form to the user in real-time during the physical activity, and automatically implementing, without input from the user, at least a part of the remedial action via one or more of the devices. The remedial action increases least one of a deep-sleep state and sleep duration of the user.

Abstract: A mask apparatus for a respiratory treatment can permit delivery of breathable gas to a user. In one example, the mask may employ a frame and cushion to form a seal for both mouth and nose. The frame may be adapted for coupling with a respiratory treatment apparatus so as to permit communication of a pressurized gas from the respiratory treatment apparatus. The cushion, which may be foam, may have a substantially under the nose configuration or over the nose configuration. The mask may have a common plenum chamber for both nose and mouth. The cushion may further define a centrally open lip superior region. The cushion may be adapted to couple with the frame directly or to the frame in conjunction with a cushion support clip. Various features of the cushion may further promote sealing and comfort for the under the nose design.

Abstract: A mask apparatus for a respiratory treatment can permit delivery of breathable gas to a user. In one example, the mask may employ a frame and cushion to form a seal for both mouth and nose. The frame may be adapted for coupling with a respiratory treatment apparatus so as to permit communication of a pressurized gas from the respiratory treatment apparatus. The cushion, which may be foam, may have a substantially under the nose configuration or over the nose configuration. The mask may have a common plenum chamber for both nose and mouth. The cushion may further define a centrally open lip superior region. The cushion may be adapted to couple with the frame directly or to the frame in conjunction with a cushion support clip. Various features of the cushion may further promote sealing and comfort for the under the nose design.

Abstract: A mask apparatus for a respiratory treatment can permit delivery of breathable gas to a user. In one example, the mask may employ a frame and cushion to form a seal for both mouth and nose. The frame may be adapted for coupling with a respiratory treatment apparatus so as to permit communication of a pressurized gas from the respiratory treatment apparatus. The cushion, which may be foam, may have a substantially under the nose configuration or over the nose configuration. The mask may have a common plenum chamber for both nose and mouth. The cushion may further define a centrally open lip superior region. The cushion may be adapted to couple with the frame directly or to the frame in conjunction with a cushion support clip. Various features of the cushion may further promote sealing and comfort for the under the nose design.

Abstract: A mask apparatus for a respiratory treatment can permit delivery of breathable gas to a user. In one example, the mask may employ a frame and cushion to form a seal for both mouth and nose. The frame may be adapted for coupling with a respiratory treatment apparatus so as to permit communication of a pressurized gas from the respiratory treatment apparatus. The cushion, which may be foam, may have a substantially under the nose configuration or over the nose configuration. The mask may have a common plenum chamber for both nose and mouth. The cushion may further define a centrally open lip superior region. The cushion may be adapted to couple with the frame directly or to the frame in conjunction with a cushion support clip. Various features of the cushion may further promote sealing and comfort for the under the nose design.

Abstract: A mask apparatus for a respiratory treatment can permit delivery of breathable gas to a user. In one example, the mask may employ a frame and cushion to form a seal for both mouth and nose. The frame may be adapted for coupling with a respiratory treatment apparatus so as to permit communication of a pressurized gas from the respiratory treatment apparatus. The cushion, which may be foam, may have a substantially under the nose configuration or over the nose configuration. The mask may have a common plenum chamber for both nose and mouth. The cushion may further define a centrally open lip superior region. The cushion may be adapted to couple with the frame directly or to the frame in conjunction with a cushion support clip. Various features of the cushion may further promote sealing and comfort for the under the nose design.

Abstract: A system and method for performing multiple user authentications with a single sign-on is disclosed. This system and method begins when the user performs a first user authentication, with user name and password, within the user's Intranet. Then the user selects a remote server subsequent to the first authentication. The server in the Intranet sends a token to the remote server containing authentication information made available because of the first authentication. Finally, the remote server decodes the authentication information, which has the effect within the remote server of performing a second user authentication without the user needing to sign-on a second time.

Abstract: A closet device or wardrobe whereby cross-supports to the bars for hanging clothing lead to increased stability and load capacity. A cross-support is simply connected to the top of the frame and can be a wire with bends at its two ends and two body sections that lead to a middle section wherein an obtuse angle is made as the two halves of the cross-support come together. The bends hook or hang on opposite sides of the upper frame of the wardrobe . The hang bar can rest on the angled middle section of the cross support, which provides additional support to the hang bar from the usual connections of the hang bar to the frame at the hang bar's two ends. This additional support to the hang bar results in increased stability, durability and load capacity for the wardrobe or closet device. The cross support can be in the form of a wire, a tube a rod, a beam, or any other structural type supporting element.

Abstract: An automatic titration apparatus for optically determining incompatibility of petroleum oils. The apparatus includes reservoirs for oil and solvent, a sealed temperature-controlled mixing vessel, including a liquid mixer, pumps and transfer lines for dispensing oil and solvent from said reservoirs to said mixing vessel wherein oil and solvent are mixed to form a mixture, an aggregate detector, transfer lines for transferring said mixture to the aggregate detector, and a computer programmed to operate and monitor all elements of said apparatus.

Abstract: An optical alignment device is provided comprising a base portion extending the length of the alignment device, a substantially horizontal package mounting portion coupled to the base portion, and a component retaining portion coupled to the base portion.

Abstract: A EEPROM cell design, and a method of fabrication for the EEPROM cell, has been developed. The EEPROM cell includes a polysilicon control gate structure, polysilicon select gate structures, and novel polysilicon, floating gate spacer structures, fabricated using deposition and anisotropic etching, sidewall processes. The use of floating gate spacers, allows density improvements to be realized. The EEPROM cell can programmed, read, and erased, using only biasing conditions, without having to use UV light for the erase cycle.

Abstract: A EEPROM cell design, and a method of fabrication for the EEPROM cell, has been developed. The EEPROM cell includes a polysilicon control gate structure, polysilicon select gate structures, and novel polysilicon, floating gate spacer structures, fabricated using deposition and anisotropic etching, sidewall processes. The use of floating gate spacers, allows density improvements to be realized. The EEPROM cell can programmed, read, and erased, using only biasing conditions, without having to use UV light for the erase cycle.