Patents by Inventor James T. Kellis

James T. Kellis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROTEASE VARIANTS AND USES THEREOF
    Publication number: 20250092336
    Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.
    Type: Application
    Filed: October 14, 2024
    Publication date: March 20, 2025
    Inventors: Joshua Roy Basler, Michael Stoner, James T. Kellis, Jr., Adam Garske, David Marquez, Katherine Augustyn, Priyanka Chandrasekaran, Miles Christopher Scotcher, Lilia Maria Babe, Richard R. Bott, David A. Estell, Gudrun Vogtentanz, Sina Pricelius, Jian Yao
  • Compositions and methods comprising protease variants
    Patent number: 12203112
    Abstract: The present invention provides protease variants comprising three amino acid substitutions selected from X101N, X128S, and X217Q, compositions comprising such protease variants, and methods of using such protease variants and compositions.
    Type: Grant
    Filed: December 10, 2021
    Date of Patent: January 21, 2025
    Assignee: Danisco US Inc.
    Inventors: Ayrookaran J. Poulose, Joshua Roy Basler, Luis G. Cascao-Pereira, James T. Kellis, Jr., Alexander Pisarchik, Daniel Esteban Torres Pazmino, David A. Estell
  • Protease variants and uses thereof
    Patent number: 12146122
    Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.
    Type: Grant
    Filed: April 17, 2023
    Date of Patent: November 19, 2024
    Assignee: Danisco US Inc.
    Inventors: Joshua Roy Basler, Michael Stoner, James T. Kellis, Jr., Adam Garske, David Marquez, Katherine Augustyn, Priyanka Chandrasekaran, Miles Christopher Scotcher, Lilia Maria Babe, Richard R. Bott, David A. Estell, Gudrun Vogtentanz, Sina Pricelius, Jian Yao
  • COMPOSITIONS AND METHODS COMPRISING SERINE PROTEASE VARIANTS
    Publication number: 20240191220
    Abstract: The present invention provides serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.
    Type: Application
    Filed: October 9, 2023
    Publication date: June 13, 2024
    Inventors: Viktor Yuryevich Alekseyev, Neelam S. Amin, Luis G. Cascao-Pereira, Katherine D. Collier, David A. Estell, James T. Kellis, JR., Ayrookaran J. Poulose, Philiip F. Souter, Glenn S. Ward, Katherine Augustyn, Jian Yao
  • PROTEASE VARIANTS AND USES THEREOF
    Publication number: 20240093124
    Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.
    Type: Application
    Filed: April 17, 2023
    Publication date: March 21, 2024
    Inventors: Joshua Roy Basler, Michael Stoner, James T. Kellis, Jr., Adam Garske, David Marquez, Katherine Augustyn, Priyanka Chandrasekaran, Miles Christopher Scotcher, Lilia Maria Babe, Richard R. Bott, David A. Estell, Gudrun Vogtentanz, Sina Pricelius, Jian Yao
  • Protease variants and uses thereof
    Patent number: 11661567
    Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.
    Type: Grant
    Filed: May 31, 2017
    Date of Patent: May 30, 2023
    Assignee: Danisco US Inc.
    Inventors: David Marquez, Michael Stoner, James T. Kellis, Jr., Adam Garske, Joshua Roy Basler, Katherine Augustyn, Priyanka Chandrasekaran, Miles Christopher Scotcher, Lilia Maria Babe, Richard R. Bott, David A. Estell, Gudrun Vogtentanz, Sina Pricelius, Jian Yao
  • subtilisin protease variants and compositions comprising the same
    Patent number: 11447762
    Abstract: The present invention provides serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.
    Type: Grant
    Filed: July 10, 2018
    Date of Patent: September 20, 2022
    Assignee: Danisco US Inc.
    Inventors: Viktor Yuryevich Alekseyev, Neelam S. Amin, Luis G. Cascao-Pereira, Katherine D. Collier, David A. Estell, James T. Kellis, Jr., Ayrookaran J. Poulose, Philip F. Souter, Glenn S. Ward, Katherine Augustyn, Jian Yao
  • Fabric and home care products comprising cold water proteases
    Patent number: 10900000
    Abstract: This invention relates to fabric and home care products comprising one or more cold water proteases and processes for making and using such products. Such compositions provide improved cleaning and freshness. Such cold water proteases may be derived from parent enzymes, including BPN? subtilisin and subtilisin derived from Bacillus lentus, by substitution, insertion and/or deletion of one or more of the parent enzymes' amino acids.
    Type: Grant
    Filed: December 13, 2017
    Date of Patent: January 26, 2021
    Assignee: The Procter & Gamble Company
    Inventors: Philip Frank Souter, Glenn Steven Ward, Viktor Yuryevich Alekseyev, Joshua Roy Basler, Luis Gustavo Cascao-Pereira, David A Estell, Ayrookaran J Poulose, James T Kellis, Jr., Alexander Pisarchik, Daniel Torres-Pazmino
  • COMPOSITIONS AND METHODS COMPRISING PROTEASE VARIANTS
    Publication number: 20200080069
    Abstract: The present invention provides protease variants, compositions comprising protease variants, and methods of using such protease variants and compositions.
    Type: Application
    Filed: November 25, 2019
    Publication date: March 12, 2020
    Inventors: Ayrookaran J. Poulose, Joshua Roy Basler, Luis G. Cascao-Pereira, James T. Kellis, JR., Alexander Pisarchik, Daniel Esteban Torres Pazmino, David A. Estell
  • Compositions and methods comprising variant microbial proteases
    Patent number: 10563189
    Abstract: The present invention provides variant subtilisins and compositions comprising at least one variant subtilisin set forth herein, as well as methods for using these variants and compositions. In some embodiments, the present invention provides variant subtilisins suitable for laundry cleaning applications.
    Type: Grant
    Filed: November 10, 2014
    Date of Patent: February 18, 2020
    Assignee: The Procter & Gamble Company
    Inventors: Joshua R. Basler, Luis G. Cascao-Pereira, David A. Estell, James T. Kellis, Jr.
  • COMPOSITIONS AND METHODS COMPRISING SERINE PROTEASE VARIANTS
    Publication number: 20190136217
    Abstract: The present invention provides serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.
    Type: Application
    Filed: July 10, 2018
    Publication date: May 9, 2019
    Inventors: Viktor Yuryevich Alekseyev, Neelam S. Amin, Luis G. Cascao-Pereira, Katherine D. Collier, David A. Estell, James T. Kellis, JR., Ayrookaran J. Poulose, Philip F. Souter, Glenn S. Ward, Katherine Augustyn, Jian Yao
  • Compositions and methods comprising serine protease variants
    Patent number: 10093887
    Abstract: The present invention provides methods for protein engineering and serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.
    Type: Grant
    Filed: July 21, 2014
    Date of Patent: October 9, 2018
    Assignee: DANISCO US INC.
    Inventors: Wolfgang Aehle, Luis G. Cascao-Pereira, David A. Estell, Frits Goedegebuur, James T. Kellis, Jr., Ayrookaran J. Poulose, Brian F. Schmidt
  • COMPOSITIONS AND METHODS COMPRISING VARIANT MICROBIAL PROTEASES
    Publication number: 20180223269
    Abstract: The present invention provides variant subtilisins and compositions comprising at least one variant subtilisin set forth herein, as well as methods for using these variants and compositions. In some embodiments, the present invention provides variant proteases suitable for laundry cleaning applications.
    Type: Application
    Filed: August 15, 2017
    Publication date: August 9, 2018
    Inventors: LUIS G. CASCAO-PEREIRA, James T. Kellis, JR., Viktor Yuryevich Alekseyev, Alexander Pisarchik
  • COMPOSITIONS AND METHODS COMPRISING SERINE PROTEASE VARIANTS
    Publication number: 20180216092
    Abstract: The present invention provides serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.
    Type: Application
    Filed: December 5, 2017
    Publication date: August 2, 2018
    Inventors: VIKTOR YURYEVICH ALEKSEYEV, Neelam S. Amin, Luis G. Cascao-Pereira, Katherine D. Collier, David A. Estell, James T. Kellis, JR., Ayrookaran J. Poulose, Philip F. Souter, Glenn S. Ward, Katherine Augustyn, Jian Yao
  • FABRIC AND HOME CARE PRODUCTS
    Publication number: 20180171268
    Abstract: This invention relates to fabric and home care products comprising one or more cold water proteases and processes for making and using such products. Such compositions provide improved cleaning and freshness. Such cold water proteases may be derived from parent enzymes, including BPN? subtilisin and subtilisin derived from Bacillus lentus, by substitution, insertion and/or deletion of one or more of the parent enzymes' amino acids.
    Type: Application
    Filed: December 13, 2017
    Publication date: June 21, 2018
    Inventors: Philip Frank Souter, Glenn Steven Ward, Viktor Yuryevich Alekseyev, Joshua Roy Basler, Luis Gustavo Cascao-Pereira, David A Estell, Ayrookaran J Poulose, James T Kellis, JR., Alexander Pisarchik, Daniel Torres-Pazmino
  • COMPOSITIONS AND METHODS COMPRISING VARIANT MICROBIAL PROTEASES
    Publication number: 20180051269
    Abstract: The present invention provides variant subtilisins and compositions comprising at least one variant subtilisin set forth herein, as well as methods for using these variants and compositions. In some embodiments, the present invention provides variant subtilisins suitable for laundry cleaning applications.
    Type: Application
    Filed: November 2, 2017
    Publication date: February 22, 2018
    Inventors: Joshua R. Basler, Luis G. Cascao-Pereira, David A. Estell, James T. Kellis, JR.
  • Compositions and methods comprising serine protease variants
    Patent number: 9856466
    Abstract: The present invention provides serine protease variants, more specifically subtilisin variants produced there from. Specifically, the present invention provides serine protease variants, more specifically subtilisin variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants, more specifically subtilisin variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants, more specifically subtilisin variants.
    Type: Grant
    Filed: May 4, 2012
    Date of Patent: January 2, 2018
    Assignee: DANISCO US INC.
    Inventors: Neelam S. Amin, Katherine Augustyn, Joshua R. Basler, Luis G. Cascao-Pereira, Katherine D. Collier, Edward M. Concar, David A. Estell, James T. Kellis, Jr., Euan John Magennis, Alexander Pisarchik, Ayrookaran J. Poulose, Philip Frank Souter, Glenn Steven Ward, Jian Yao
  • COMPOSITIONS AND METHODS COMPRISING PROTEASE VARIANTS
    Publication number: 20160083710
    Abstract: The present invention provides protease variants, compositions comprising protease variants, and methods of using such protease variants and compositions.
    Type: Application
    Filed: September 2, 2015
    Publication date: March 24, 2016
    Inventors: Joshua Roy Basler, Luis Gustavo Cacao-Pereira, David A. Estell, James T. Kellis, Alexander Pisarchik, Ayrookaran J. Poulose, Daniel Torres-Pazmino
  • METHODS FOR IMPROVING MULTIPLE PROTEIN PROPERTIES
    Publication number: 20160032267
    Abstract: The present invention provides efficient methods for obtaining a protein with one or more beneficial attributes in industrial, consumer or pharmaceutical applications. In some preferred embodiments, the present invention provides methods for producing superior enzymes for a given application through screening an abbreviated set of candidate enzymes.
    Type: Application
    Filed: August 7, 2015
    Publication date: February 4, 2016
    Applicant: DANISCO US INC.
    Inventors: Luis G. Cascao-Pereira, David A. Estell, James T. Kellis, Ayrookaran J. Poulose
  • PROTEASES COMPRISING ONE OR MORE COMBINABLE MUTATIONS
    Publication number: 20160010072
    Abstract: The present invention provides engineered protease variants. In particular, the protease variants comprise combinable mutations at selected surface positions that affect the charge and/or hydrophobicity of the enzyme to enhance at least one desired property of the resulting variant enzyme in a chosen application. Compositions comprising the protease variants, and methods for using the same are also provided.
    Type: Application
    Filed: June 29, 2015
    Publication date: January 14, 2016
    Inventors: Wolfgang Aehle, Luis G. Cascao-Pereira, David A. Estell, Frits Goedegebuur, James T. Kellis, Ayrookaran J. Poulose, Brian F. Schmidt