Patents by Inventor James T. Kellis, Jr.

James T. Kellis, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and Methods Comprising Variant Microbial Proteases
    Publication number: 20150247140
    Abstract: The present invention provides variant subtilisins and compositions comprising at least one variant subtilisin set forth herein, as well as methods for using these variants and compositions. In some embodiments, the present invention provides variant proteases suitable for laundry cleaning applications.
    Type: Application
    Filed: March 2, 2015
    Publication date: September 3, 2015
    Applicant: DANISCO US INC.
    Inventors: Viktor Yuryevich Alekseyev, Luis G. Cascao-Pereira, James T. Kellis, JR., Alexander Pisarchik
  • Proteases comprising one or more combinable mutations
    Patent number: 9096838
    Abstract: The present invention provides engineered protease variants. In particular, the protease variants comprise combinable mutations at selected surface positions that affect the charge and/or hydrophobicity of the enzyme to enhance at least one desired property of the resulting variant enzyme in a chosen application. Compositions comprising the protease variants, and methods for using the same are also provided.
    Type: Grant
    Filed: May 2, 2014
    Date of Patent: August 4, 2015
    Assignee: Danisco US Inc.
    Inventors: Luis G. Cascao-Pereira, David A. Estell, James T. Kellis, Jr.
  • ISOPRENE SYNTHASE VARIANTS FOR IMPROVED MICROBIAL PRODUCTION OF ISOPRENE
    Publication number: 20150191712
    Abstract: The present invention provides methods and compositions comprising at least one isoprene synthase enzyme with improved catalytic activity and/or solubility. In particular, the present invention provides variant plant isoprene synthases for increased isoprene production in microbial host cells. Biosynthetically produced isoprene of the present invention finds use in the manufacture of rubber and elastomers.
    Type: Application
    Filed: November 17, 2014
    Publication date: July 9, 2015
    Inventors: Richard R. BOTT, Marguerite A. Cervin, James T. Kellis, JR., Joseph C. Mcauliffe, Andrei Miasnikov, Caroline M. Peres, Christopher L. Rife, Derek H. Wells, Walter Weyler, Gregory M. Whited
  • COMPOSITIONS AND METHODS COMPRISING SERINE PROTEASE VARIANTS
    Publication number: 20150132825
    Abstract: The present invention provides methods for protein engineering and serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.
    Type: Application
    Filed: November 10, 2014
    Publication date: May 14, 2015
    Applicant: DANISCO US INC.
    Inventors: Wolfgang Aehle, Luis G. Cascao-Pereira, David A. Estell, Frits Goedegebuur, James T. Kellis, JR., Ayrookaran J. Poulose, Brian F. Schmidt
  • COMPOSITIONS AND METHODS COMPRISING SERINE PROTEASE VARIANTS
    Publication number: 20150125925
    Abstract: The present invention provides consumer products comprising a serine protease variant, more specifically subtilisin variants produced there from. Specifically, the present invention provides consumer products comprising a serine protease variant, more specifically a subtilisin variant having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides methods of making such compositions and methods of treating surfaces, particularly fabric surfaces comprising contacting a surface with an aqueous liquor comprising a serine protease variant, more specifically subtilisin variants and an adjunct material.
    Type: Application
    Filed: November 5, 2013
    Publication date: May 7, 2015
    Applicant: The Procter & Gamble Company
    Inventors: Philip Frank SOUTER, Euan John MAGENNIS, Glenn Steven WARD, Neelam S. AMIN, Katherine AUGUSTYN, Joshua R. BASLER, Luis Gustavo CASCAO-PEREIRA, Katherine D. COLLIER, Edward M. CONCAR, David A. ESTELL, James T. KELLIS, JR., Alexander PISARCHIK, Ayrookaran Joseph POULOSE, Jian YAO
  • PROTEASES COMPRISING ONE OR MORE COMBINABLE MUTATIONS
    Publication number: 20150065412
    Abstract: The present invention provides engineered protease variants. In particular, the protease variants comprise combinable mutations at selected surface positions that affect the charge and/or hydrophobicity of the enzyme to enhance at least one desired property of the resulting variant enzyme in a chosen application. Compositions comprising the protease variants, and methods for using the same are also provided.
    Type: Application
    Filed: November 10, 2014
    Publication date: March 5, 2015
    Applicant: DANISCO US INC.
    Inventors: Luis G. Cascao-Pereira, David A. Estell, James T. Kellis, JR.
  • Compositions and Methods Comprising Variant Microbial Proteases
    Publication number: 20150056682
    Abstract: The present invention provides variant subtilisins and compositions comprising at least one variant subtilisin set forth herein, as well as methods for using these variants and compositions. In some embodiments, the present invention provides variant proteases suitable for laundry cleaning applications.
    Type: Application
    Filed: November 10, 2014
    Publication date: February 26, 2015
    Applicant: DANISCO US INC.
    Inventors: Viktor Yuryevich Alekseyev, Luis G. Cascao-Pereira, James T. Kellis, JR., Alexander Pisarchik
  • TS-23 alpha-amylase variants with altered properties
    Patent number: 8962283
    Abstract: Described are variants (mutants) of a parent alpha-amylase having alpha-amylase activity and exhibiting altered properties relative to the parent alpha-amylase, and methods of use, thereof.
    Type: Grant
    Filed: May 21, 2013
    Date of Patent: February 24, 2015
    Assignee: Danisco US Inc.
    Inventors: Luis G. Cascao-Pereira, Claudine Chang, Clement Choy, James T. Kellis, Jr., Brian E. Jones, Melodie Estabrook, Marc Kolkman, Chris Leeflang, Casper Vroemen, Walter Weyler
  • COMPOSITIONS AND METHODS COMPRISING SERINE PROTEASE VARIANTS
    Publication number: 20150031589
    Abstract: The present invention provides methods for protein engineering and serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.
    Type: Application
    Filed: July 21, 2014
    Publication date: January 29, 2015
    Applicant: DANISCO US INC.
    Inventors: Wolfgang Aehle, Luis G. Cascao-Pereira, David A. Estell, Frits Goedegebuur, James T. Kellis, JR., Ayrookaran J. Poulose, Brian F. Schmidt
  • Isoprene synthase variants for improved microbial production of isoprene
    Patent number: 8916370
    Abstract: The present invention provides methods and compositions comprising at least one isoprene synthase enzyme with improved catalytic activity and/or solubility. In particular, the present invention provides variant plant isoprene synthases for increased isoprene production in microbial host cells. Biosynthetically produced isoprene of the present invention finds use in the manufacture of rubber and elastomers.
    Type: Grant
    Filed: March 30, 2012
    Date of Patent: December 23, 2014
    Assignees: Danisco US Inc., The Goodyear Tire & Rubber Company
    Inventors: Richard R. Bott, Marguerite A. Cervin, James T. Kellis, Jr., Joseph C. McAuliffe, Andrei Miasnikov, Caroline M. Peres, Christopher Lee Rife, Derek H. Wells, Walter Weyler, Gregory M. Whited
  • PROTEASES COMPRISING ONE OR MORE COMBINABLE MUTATIONS
    Publication number: 20140308736
    Abstract: The present invention provides engineered protease variants. In particular, the protease variants comprise combinable mutations at selected surface positions that affect the charge and/or hydrophobicity of the enzyme to enhance at least one desired property of the resulting variant enzyme in a chosen application. Compositions comprising the protease variants, and methods for using the same are also provided.
    Type: Application
    Filed: May 2, 2014
    Publication date: October 16, 2014
    Applicant: DANISCO US INC.
    Inventors: Luis G. Cascao-Pereira, David A. Estell, James T. Kellis, JR.
  • Compositions and Methods Comprising Protease Variants
    Publication number: 20140273177
    Abstract: The present invention provides protease variants, compositions comprising protease variants, and methods of using such protease variants and compositions.
    Type: Application
    Filed: March 25, 2014
    Publication date: September 18, 2014
    Applicant: DANISCO US INC.
    Inventors: Joshua Roy Basler, Luis Gustavo Cascao-Pereira, David A. Estell, James T. Kellis, JR., Alexander Pisarchik, Ayrookaran J. Poulose, Daniel Torres-Pazmino
  • Fabric and home care products comprising cold water proteases
    Patent number: 8785171
    Abstract: This invention relates to fabric and home care products comprising one or more cold water proteases and processes for making and using such products. Such compositions provide improved cleaning and freshness. Such cold water proteases may be derived from parent enzymes, including BPN? subtilisin and subtilisin derived from Bacillus lentus, by substitution, insertion and/or deletion of one or more of the parent enzymes' amino acids.
    Type: Grant
    Filed: December 9, 2010
    Date of Patent: July 22, 2014
    Assignee: The Procter & Gamble Company
    Inventors: Philip Frank Souter, Glenn Steven Ward, Viktor Yuryevich Alekseyev, Joshua Roy Basler, Luis Gustavo Cascão-Pereira, David A. Estell, Ayrookaran J. Poulose, James T. Kellis, Jr., Alexander Pisarchik, Daniel Esteban Torres-Pazmino
  • FABRIC AND HOME CARE PRODUCTS
    Publication number: 20140193888
    Abstract: This invention relates to fabric and home care products comprising one or more cold water proteases and processes for making and using such products. Such compositions provide improved cleaning and freshness. Such cold water proteases may be derived from parent enzymes, including BPN? subtilisin and subtilisin derived from Bacillus lentus, by substitution, insertion and/or deletion of one or more of the parent enzymes' amino acids.
    Type: Application
    Filed: March 12, 2014
    Publication date: July 10, 2014
    Applicant: The Procter & Gamble Company
    Inventors: Philip Frank SOUTER, Glenn Steven WARD, Viktor Yuryevich ALEKSEYEV, Joshua Roy BASLER, Luis Gustavo CASAO-PEREIRA, David A ESTELL, Ayrookaran J Poulose, James T KELLIS, JR., Alexander PISARCHIK, Daniel TORRES-PAZMINO
  • Protease comprising one or more combinable mutations
    Patent number: 8753861
    Abstract: The present invention provides engineered protease variants. In particular, the protease variants comprise combinable mutations at selected surface positions that affect the charge and/or hydrophobicity of the enzyme to enhance at least one desired property of the resulting variant enzyme in a chosen application. Compositions comprising the protease variants, and methods for using the same are also provided.
    Type: Grant
    Filed: November 10, 2009
    Date of Patent: June 17, 2014
    Assignee: Danisco US Inc.
    Inventors: Luis G. Cascao-Pereira, David A. Estell, James T. Kellis, Jr.
  • Compositions and Methods Comprising Serine Protease Variants
    Publication number: 20140154782
    Abstract: The present invention provides serine protease variants, more specifically subtilisin variants produced there from. Specifically, the present invention provides serine protease variants, more specifically subtilisin variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants, more specifically subtilisin variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants, more specifically subtilisin variants.
    Type: Application
    Filed: May 4, 2012
    Publication date: June 5, 2014
    Applicant: DANISCO US INC.
    Inventors: Neelam S. Amin, Katherine Augustyn, Joshua R. Basler, Luis G. Cascao-Pereira, Katherine D. Collier, Edward M. Concar, David A. Estell, James T. Kellis, JR., Euan John Magennis, Alexander Pisarchik, Ayrookaran J. Poulose, Philip Frank Souter, Glenn Steven Ward, Jian Yao
  • Compositions and methods comprising protease variants
    Patent number: 8728790
    Abstract: The present invention provides protease variants, compositions comprising protease variants, and methods of using such protease variants and compositions.
    Type: Grant
    Filed: December 9, 2010
    Date of Patent: May 20, 2014
    Assignee: Danisco US Inc.
    Inventors: Joshua R Basler, Luis G Cascão-Pereira, David A Estell, James T Kellis, Jr., Alexander Pisarchik, Ayrookaran J. Poulose, Daniel E. Torres Pazmino
  • TS-23 Alpha-Amylase Variants With Altered Properties
    Publication number: 20130344542
    Abstract: Described are variants (mutants) of a parent alpha-amylase having alpha-amylase activity and exhibiting altered properties relative to the parent alpha-amylase, and methods of use, thereof.
    Type: Application
    Filed: May 21, 2013
    Publication date: December 26, 2013
    Inventors: Luis G. Cascao-Pereira, Claudine Chang, Clement Choy, James T. Kellis, JR., Brian E. Jones, Melodie Estabrook, Marc Kolkman, Chris Leeflang, Casper Vroemen, Walter Weyler
  • COMPOSITIONS AND METHODS COMPRISING SERINE PROTEASE VARIANTS (AS AMENDED)
    Publication number: 20130260438
    Abstract: The present invention provides serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.
    Type: Application
    Filed: May 5, 2011
    Publication date: October 3, 2013
    Applicant: Danisco US Inc.
    Inventors: Viktor Yuryevich Alekseyev, Neelam A Amin, Katherine Auguslyn, Luis Gustavo Cascao-Pereira, Katherine D. Collier, David A. Estell, James T. Kellis, JR., Ayrookaran J. Poulose, Philip Frank Souter, Glenn Steven Ward, Jian Yao
  • ISOPRENE SYNTHASE VARIANTS FOR IMPROVED MICROBIAL PRODUCTION OF ISOPRENE
    Publication number: 20130260432
    Abstract: The present invention provides methods and compositions comprising at least one isoprene synthase enzyme with improved catalytic activity and/or solubility. In particular, the present invention provides variant plant isoprene synthases for increased isoprene production in microbial host cells. Biosynthetically produced isoprene of the present invention finds use in the manufacture of rubber and elastomers.
    Type: Application
    Filed: March 30, 2012
    Publication date: October 3, 2013
    Applicant: Danisco US Inc.
    Inventors: Richard R. BOTT, Marguerite A. Cervin, James T. Kellis, JR., Joseph C. McAuliffe, Andrei Miasnikov, Caroline M. Peres, Christopher Lee Rife, Derek H. Wells, Walter Weyler, Gregory M. Whited