Patents by Inventor James Tepperman

James Tepperman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Universal light-switchable gene promoter system
    Patent number: 6858429
    Abstract: An artificial promoter system that can be fused upstream of any desired gene enabling reversible induction or repression of the expression of the gene at will in any suitable host cell or organisms by light is described. The design of the system is such that a molecule of the plant photoreceptor phytochrome is targeted to the specific DNA binding site in the promoter by a protein domain that is fused to the phytochrome and that specifically recognizes this binding site. This bound phytochrome, upon activation by light, recruits a second fusion protein consisting of a protein that binds to phytochrome only upon light activation and a transcriptional activation domain that activates expression of the gene downstream of the promoter.
    Type: Grant
    Filed: August 23, 2002
    Date of Patent: February 22, 2005
    Assignee: The Regents of the University of California
    Inventors: Peter H. Quail, Enamul Huq, James Tepperman, Sae Sato
  • Universal light-switchable gene promoter system
    Publication number: 20030082809
    Abstract: An artificial promoter system that can be fused upstream of any desired gene enabling reversible induction or repression of the expression of the gene at will in any suitable host cell or organisms by light is described. The design of the system is such that a molecule of the plant photoreceptor phytochrome is targeted to the specific DNA binding site in the promoter by a protein domain that is fused to the phytochrome and that specifically recognizes this binding site. This bound phytochrome, upon activation by light, recruits a second fusion protein consisting of a protein that binds to phytochrome only upon light activation and a transcriptional activation domain that activates expression of the gene downstream of the promoter.
    Type: Application
    Filed: August 23, 2002
    Publication date: May 1, 2003
    Inventors: Peter H. Quail, Enamul Huq, James Tepperman, Sae Sato