Abstract: A method for aligning multiple printing plates on a single piece of printing plate stock, whereby all plates register to one another and one or more printing press cylinders. The method includes the steps of (1) punching image and cylinder registration indices on the stock; (2) imaging a plurality of regions on the stock defining separate printing plates; (3) forming slitting indices relative to the defined plate regions; (4) forming a cylinder registration bend along at least one edge of the stock; and (5) slitting the stock into a plurality of printing plates. In one process, elongated image registration apertures, cylinder registration bends and notches and V-shaped slitting notches are successively provided to all plate regions to assure alignment of the printing plates to each other and the press cylinders.