Patents by Inventor JAMES TIEN

JAMES TIEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240156741
    Abstract: Pharmaceutical granulations having a functional coating surrounding a core containing 4-((L-valyl)oxy)butanoic acid are disclosed. The functional coatings provide for immediate release or modified release of 4-((L-valyl)oxy)butanoic acid. The pharmaceutical granulations can be used in oral pharmaceutical compositions.
    Type: Application
    Filed: January 24, 2024
    Publication date: May 16, 2024
    Inventors: SAMI KARABORNI, DANIEL M. CANAFAX, JIA-NING XIANG, WILLIAM W. XIANG, JAMES TIEN, STEFANIE THIEL, NORBERT POLLINGER, ANNETTE GRAVE
  • Publication number: 20240092727
    Abstract: Crystalline 4-((L-valyl)oxy)butanoic acid, methods of preparing crystalline 4-((L-valyl)oxy)butanoic acid, pharmaceutical compositions of crystalline 4-((L-valyl)oxy)butanoic acid, and methods of treatment using crystalline 4-((L-valyl)oxy)butanoic acid are disclosed.
    Type: Application
    Filed: August 29, 2023
    Publication date: March 21, 2024
    Inventors: JIA-NING XIANG, XUESONG XU, XUAN ZHANG, JAMES TIEN, HAO-WEI SHIH, HSIN-YI HUANG
  • Patent number: 11925710
    Abstract: Pharmaceutical granulations having a functional coating surrounding a core containing 4-((L-valyl)oxy)butanoic acid are disclosed. The functional coatings provide for immediate release or modified release of 4-((L-valyl)oxy)butanoic acid. The pharmaceutical granulations can be used in oral pharmaceutical compositions.
    Type: Grant
    Filed: June 17, 2022
    Date of Patent: March 12, 2024
    Assignee: XWPHARMA LTD.
    Inventors: Sami Karaborni, Daniel M. Canafax, Jia-Ning Xiang, William W. Xiang, James Tien, Stefanie Thiel, Norbert Pollinger, Annette Grave
  • Publication number: 20230357130
    Abstract: The present disclosure is directed synthetic methods for the preparation of 4-valyloxybutyric acid. The synthetic methods described herein employ a diverse array of protecting group strategies and reaction conditions. Additionally, the present disclosure is directed to compounds useful as synthetic intermediates in the preparation of 4-valyloxybutyric acid.
    Type: Application
    Filed: July 12, 2023
    Publication date: November 9, 2023
    Inventors: JIA-NING XIANG, HAO-WEI SHIH, XIAOMING WU, XUAN ZHANG, JAMES TIEN
  • Patent number: 11746081
    Abstract: The present disclosure is directed synthetic methods for the preparation of 4-valyloxybutyric acid. The synthetic methods described herein employ a diverse array of protecting group strategies and reaction conditions. Additionally, the present disclosure is directed to compounds useful as synthetic intermediates in the preparation of 4-valyloxybutyric acid.
    Type: Grant
    Filed: February 16, 2022
    Date of Patent: September 5, 2023
    Assignee: XWPHARMA LTD.
    Inventors: Jia-Ning Xiang, Hao-Wei Shih, Xiaoming Wu, Xuan Zhang, James Tien
  • Publication number: 20220323365
    Abstract: Pharmaceutical granulations having a functional coating surrounding a core containing 4-((L-valyl)oxy)butanoic acid are disclosed. The functional coatings provide for immediate release or modified release of 4-((L-valyl)oxy)butanoic acid. The pharmaceutical granulations can be used in oral pharmaceutical compositions.
    Type: Application
    Filed: June 17, 2022
    Publication date: October 13, 2022
    Inventors: SAMI KARABORNI, DANIEL M. CANAFAX, JIA-NING XIANG, WILLIAM W. XIANG, JAMES TIEN, STEFANIE THIEL, NORBERT POLLINGER, ANNETTE GRAVE
  • Publication number: 20220234994
    Abstract: The present disclosure is directed synthetic methods for the preparation of 4-valyloxybutyric acid. The synthetic methods described herein employ a diverse array of protecting group strategies and reaction conditions. Additionally, the present disclosure is directed to compounds useful as synthetic intermediates in the preparation of 4-valyloxybutyric acid.
    Type: Application
    Filed: February 16, 2022
    Publication date: July 28, 2022
    Inventors: JIA-NING XIANG, HAO-WEI SHIH, XIAOMING WU, XUAN ZHANG, JAMES TIEN
  • Patent number: 11395801
    Abstract: Pharmaceutical granulations having a functional coating surrounding a core containing 4-((L-valyl)oxy)butanoic acid are disclosed. The functional coatings provide for immediate release or modified release of 4-((L-valyl)oxy)butanoic acid. The pharmaceutical granulations can be used in oral pharmaceutical compositions.
    Type: Grant
    Filed: October 5, 2021
    Date of Patent: July 26, 2022
    Assignee: XWPHARMA LTD.
    Inventors: Sami Karaborni, Daniel M. Canafax, Jia-Ning Xiang, William W. Xiang, James Tien, Stefanie Thiel, Norbert Pollinger, Annette Grave
  • Publication number: 20220183977
    Abstract: Pharmaceutical granulations having a functional coating surrounding a core containing a water-soluble active pharmaceutical ingredient are disclosed. The functional coating provides for immediate release or controlled release of the active pharmaceutical ingredient. The pharmaceutical granulations can be used in oral pharmaceutical compositions.
    Type: Application
    Filed: March 4, 2022
    Publication date: June 16, 2022
    Inventors: SAMI KARABORNI, DANIEL M. CANAFAX, JIA-NING XIANG, WILLIAM W. XIANG, JAMES TIEN, NICOLAS D. KIRKLAND
  • Patent number: 11304906
    Abstract: Pharmaceutical granulations having a functional coating surrounding a core containing a water-soluble active pharmaceutical ingredient are disclosed. The functional coating provides for immediate release or controlled release of the active pharmaceutical ingredient. The pharmaceutical granulations can be used in oral pharmaceutical compositions.
    Type: Grant
    Filed: June 17, 2021
    Date of Patent: April 19, 2022
    Assignee: XWPHARMA LTD.
    Inventors: Sami Karaborni, Daniel M. Canafax, Jia-Ning Xiang, William W. Xiang, James Tien, Nicolas D. Kirkland
  • Publication number: 20220105044
    Abstract: Pharmaceutical granulations having a functional coating surrounding a core containing 4-((L-valyl)oxy)butanoic acid are disclosed. The functional coatings provide for immediate release or modified release of 4-((L-valyl)oxy)butanoic acid. The pharmaceutical granulations can be used in oral pharmaceutical compositions.
    Type: Application
    Filed: October 5, 2021
    Publication date: April 7, 2022
    Inventors: SAMI KARABORNI, DANIEL M. CANAFAX, JIA-NING XIANG, WILLIAM W. XIANG, JAMES TIEN, STEFANIE THIEL, NORBERT POLLINGER, ANNETTE GRAVE
  • Patent number: 11279669
    Abstract: The present disclosure is directed synthetic methods for the preparation of 4-valyloxybutyric acid. The synthetic methods described herein employ a diverse array of protecting group strategies and reaction conditions. Additionally, the present disclosure is directed to compounds useful as synthetic intermediates in the preparation of 4-valyloxybutyric acid.
    Type: Grant
    Filed: June 18, 2021
    Date of Patent: March 22, 2022
    Assignee: XWPHARMA LTD.
    Inventors: Jia-Ning Xiang, Hao-Wei Shih, Xiaoming Wu, Xuan Zhang, James Tien
  • Publication number: 20220055982
    Abstract: The present disclosure is directed synthetic methods for the preparation of 4-valyloxybutyric acid. The synthetic methods described herein employ a diverse array of protecting group strategies and reaction conditions. Additionally, the present disclosure is directed to compounds useful as synthetic intermediates in the preparation of 4-valyloxybutyric acid.
    Type: Application
    Filed: June 18, 2021
    Publication date: February 24, 2022
    Inventors: JIA-NING XIANG, HAO-WEI SHIH, XIAOMING WU, XUAN ZHANG, JAMES TIEN
  • Publication number: 20210393529
    Abstract: Pharmaceutical granulations having a functional coating surrounding a core containing a water-soluble active pharmaceutical ingredient are disclosed. The functional coating provides for immediate release or controlled release of the active pharmaceutical ingredient. The pharmaceutical granulations can be used in oral pharmaceutical compositions.
    Type: Application
    Filed: June 17, 2021
    Publication date: December 23, 2021
    Inventors: SAMI KARABORNI, DANIEL M. CANAFAX, JIA-NING XIANG, WILLIAM W. XIANG, JAMES TIEN
  • Patent number: 8421796
    Abstract: The present invention provides a visualization method and apparatus for multidimensional data. According to an embodiment, there is provided a visualization method for multidimensional data including a plurality of parameters to be viewed which are related to a given object, including: displaying the plurality of parameters to be viewed which are related to a given object in different layers along a Z axis of a 3-D coordinate system, wherein each of the plurality of parameters is displayed in a 2-D plane; determining one of the 2-D planes as an interested plane; and in response to focusing on an object instance of the object by a user, linking and displaying locations of the object instance on other planes.
    Type: Grant
    Filed: February 5, 2009
    Date of Patent: April 16, 2013
    Assignee: International Business Machines Corporation
    Inventors: Song Song, James Tien-Cheng Yeh, Jie Xin Jiao, Xiao Feng Wang, Peng Zhu, Ying Wang
  • Patent number: 8140869
    Abstract: The present invention provides a central power management method and system, a device side agent and a central power management controller. The central power management method includes: registering a plurality of devices, wherein at least power management capabilities associated with controllable statuses of power management of each of the plurality of devices are recorded; collecting running status data from each of the plurality of devices; analyzing the running status data to determine a current power management policy for each of the plurality of devices; and for each of the plurality of devices, controlling running status thereof according to the current power management policy determined for the device and the power management capabilities of the device.
    Type: Grant
    Filed: February 5, 2009
    Date of Patent: March 20, 2012
    Assignee: International Business Machines Corporation
    Inventors: Song Song, Chang Jie Guo, Xiao Feng Wang, James Tien-Cheng Yeh
  • Patent number: 7984115
    Abstract: An extensible client-server application platform. Execution of functions may require interactions between client-side and server-side components. Extensions may be provided as pairs of modules, one for the client and one for the server, that interact when performing an extension function. To ensure that the client-side and server-side interact appropriately, extensions modules may be initially supplied to the server and downloaded as appropriate, to the client. An enterprise business intelligence application is used as an example of the extensible client-server application platform. To enable use of third party extension modules, the server-side components may execute on a virtualized server.
    Type: Grant
    Filed: December 8, 2006
    Date of Patent: July 19, 2011
    Assignee: Microsoft Corporation
    Inventors: Ian Robert James Tien, Corey Hulen, Chen-I Lim
  • Publication number: 20090210726
    Abstract: The present invention provides a central power management method and system, a device side agent and a central power management controller. The central power management method includes: registering a plurality of devices, wherein at least power management capabilities associated with controllable statuses of power management of each of the plurality of devices are recorded; collecting running status data from each of the plurality of devices; analyzing the running status data to determine a current power management policy for each of the plurality of devices; and for each of the plurality of devices, controlling running status thereof according to the current power management policy determined for the device and the power management capabilities of the device.
    Type: Application
    Filed: February 5, 2009
    Publication date: August 20, 2009
    Inventors: Song Song, Chang Jie Guo, Xiao Feng Wang, James Tien-Cheng Yeh
  • Publication number: 20090207166
    Abstract: The present invention provides a visualization method and apparatus for multidimensional data. According to an embodiment, there is provided a visualization method for multidimensional data including a plurality of parameters to be viewed which are related to a given object, including: displaying the plurality of parameters to be viewed which are related to a given object in different layers along a Z axis of a 3-D coordinate system, wherein each of the plurality of parameters is displayed in a 2-D plane; determining one of the 2-D planes as an interested plane; and in response to focusing on an object instance of the object by a user, linking and displaying locations of the object instance on other planes.
    Type: Application
    Filed: February 5, 2009
    Publication date: August 20, 2009
    Inventors: Song Song, James Tien-Cheng Yeh, Jie Xin Jiao, Xiao Feng Wang, Peng Zhu, Ying Wang
  • Patent number: 7478048
    Abstract: This invention discloses a system for creating voice XML file automatically, comprising: a graphic user interface for defining a plurality of icons, wherein each of said icons corresponds to one or more attributes of voice XML; voice XML tag generator for interpreting said action stream based on a library of voice XML tags, generating the corresponding voice XML tags; and, voice XML file generator for combing the contents to be played with the tags generated by the voice XML tag generator according voice XML syntax, for creating the voice XML file. This system can create the voice XML file for the TTS voice XML file or the real-time-recorded audio voice XML file.
    Type: Grant
    Filed: July 29, 2003
    Date of Patent: January 13, 2009
    Assignee: International Business Machines Corporation
    Inventors: James Tien-Cheng Yeh, Hiu Su, Qianying Wang