Abstract: Embodiments of the present disclosure provide for systems for removing contaminants from a leachate, methods of removing contaminants from a leachate, and the like.

Abstract: Embodiments of the present invention described herein relate to vacuum cleaners. The vacuum cleaners described herein can include a motor, a lid, a collection receptacle, and at least one support member to permit access to the interior of the vacuum cleaner. Also described herein are vacuum cleaners having a motor, a lid, a collection receptacle, and an accessory holder that can be pivotally mounted to the collection receptacle to permit access to the contents thereof.

Abstract: A simulation workflow manager obtains a set of parameters for simulation of a system and training of a reinforcement learning model for optimizing an application of the system. In response to obtaining the set of parameters, the simulation workflow manager configures a first compute node that includes a training application for training the reinforcement learning model. The simulation workflow manager also configures a second compute note with a simulation application to perform the simulation of the system in a simulation environment. Data is generated through execution of the simulation in the second compute node that is provided to the first compute node to cause the training application to use the data to train the reinforcement learning model.

Abstract: The present invention covers substituted. Pyrazolo-pyrrolo-pyrimidine-dione (PPPD) compounds of general formula (I): in which R1, R2 and R3 are as defined herein, methods of preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of neurogenic diseases, as a sole agent or in combination with other active ingredients.

Abstract: A simulation workflow manager obtains a set of parameters for simulation of a system and training of a reinforcement learning model for optimizing an application of the system. In response to obtaining the set of parameters, the simulation workflow manager configures a first compute node that includes a training application for training the reinforcement learning model. The simulation workflow manager also configures a second compute note with a simulation application to perform the simulation of the system in a simulation environment. Data is generated through execution of the simulation in the second compute node that is provided to the first compute node to cause the training application to use the data to train the reinforcement learning model.

Abstract: Embodiments of the present invention described herein relate to vacuum cleaners. The vacuum cleaners described herein can include a motor, a lid, a collection receptacle, and at least one support member to permit access to the interior of the vacuum cleaner. Also described herein are vacuum cleaners having a motor, a lid, a collection receptacle, and an accessory holder that can be pivotally mounted to the collection receptacle to permit access to the contents thereof.

Abstract: The present invention covers substituted. Pyrazolo-pyrrolo-pyrimidine-dione (PPPD) compounds of general formula (I): in which R1, R2 and R3 are as defined herein, methods of preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of neurogenic diseases, as a sole agent or in combination with other active ingredients.

Abstract: A series of substituted spirocyclic 2-oxoindoline derivatives, and analogues thereof, being potent modulators of human IL-17 activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including inflammatory and autoimmune disorders.

Abstract: An apparatus uses disinfecting ultraviolet light in the C spectrum (UVC) within a housing having an interior chamber. The exterior surfaces of the apparatus are provided in stainless steel suitable for a health care environment. The housing is configured to receive a variety of large devices such as walkers and wheel chairs. Once placed in the interior chamber, first and second offset sanitizing lights are turned on to sanitize the item or items disposed in the interior chamber. The offset lights provide light coverage to both ends of an item such as a wheel chair placed in the interior chamber. The interior of the chamber is lined with reflective, noduled material, to reflect light in a scattered pattern to increase coverage for the item being sanitized. A door closes the interior chamber when the lights are turned on. An interlock is used with the door to turn the lights off when the door is open.

Abstract: The invention relates to 6,5 heterobicyclic ring derivatives of formula (I), processes for preparing them, pharmaceutical compositions containing them and their use for the treatment of inflammatory conditions driven by STING activation, such as, but not confined to, SLE and geographic atrophy.

Abstract: A simulation workflow manager obtains a set of parameters for simulation of a system and training of a reinforcement learning model for optimizing an application of the system. In response to obtaining the set of parameters, the simulation workflow manager configures a first compute node that includes a training application for training the reinforcement learning model. The simulation workflow manager also configures a second compute note with a simulation application to perform the simulation of the system in a simulation environment. Data is generated through execution of the simulation in the second compute node that is provided to the first compute node to cause the training application to use the data to train the reinforcement learning model.

Abstract: A series of substituted spirocyclic 2-oxoindoline derivatives, and analogues thereof, being potent modulators of human IL-17 activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including inflammatory and autoimmune disorders.

Abstract: Embodiments of the present invention described herein relate to vacuum cleaners. The vacuum cleaners described herein can include a motor, a lid, a collection receptacle, and at least one support member to permit access to the interior of the vacuum cleaner. Also described herein are vacuum cleaners having a motor, a lid, a collection receptacle, and an accessory holder that can be pivotally mounted to the collection receptacle to permit access to the contents thereof.

Abstract: Embodiments of the present invention described herein relate to vacuum cleaners. The vacuum cleaners described herein can include a motor, a lid, a collection receptacle, and at least one support member to permit access to the interior of the vacuum cleaner. Also described herein are vacuum cleaners having a motor, a lid, a collection receptacle, and an accessory holder that can be pivotally mounted to the collection receptacle to permit access to the contents thereof.

Abstract: Embodiments of the present invention described herein relate to vacuum cleaners. The vacuum cleaners described herein can include a motor, a lid, a collection receptacle, and at least one support member to permit access to the interior of the vacuum cleaner. Also described herein are vacuum cleaners having a motor, a lid, a collection receptacle, and an accessory holder that can be pivotally mounted to the collection receptacle to permit access to the contents thereof.

Abstract: Techniques are disclosed for performing operations in an authentication token or other cryptographic device in a system comprising an authentication server. In one aspect, a code generated by the authentication server is received in the cryptographic device. The code may have associated therewith information specifying at least one operation to be performed by the cryptographic device. The cryptographic device authenticates the code, and responsive to authentication of the code, performs the specified operation. If the code is not authenticated, the operation is not performed. The code may be determined as a function of a one-time password generated by the authentication server. The function may also take as an input an identifier of the operation to be performed.

Abstract: A process of manufacturing an image transfer kit which enables the production of a desired image on a substrate which subsequently may be used in different decorative applications. The process may include the application of different layers of lacquer, photoclear and inks to a substrate in addition to the ultra-violet light treatment, washing and drying of the substrate at certain stages during the process. The produced image transfer kit may include the substrate, layers of transfer lacquer, high resolution lacquer, photoclear, clear or white ink, adhesive and the desired image.

Abstract: A multimedia device or other type of processing device comprises a memory, a processor coupled to the memory, and playback circuitry coupled to the processor. In one aspect, the processor is operative to control the storage in the memory of at least one multimedia file containing a one-time password or other type of password, where the password is generated externally to the processing device, and to control the playback of the multimedia file via the playback circuitry to make the password apparent to or otherwise accessible to an associated user or other entity. The multimedia file may comprise, for example, an audio file, with the password being presented to the user in an audible form upon playback of the audio file. As another example, the multimedia file may comprise a video file, with the password being presented to the user in a visible form upon playback of the video file.

Abstract: Techniques are disclosed for performing operations in an authentication token or other cryptographic device in a system comprising an authentication server. In one aspect, a code generated by the authentication server is received in the cryptographic device. The code may have associated therewith information specifying at least one operation to be performed by the cryptographic device. The cryptographic device authenticates the code, and responsive to authentication of the code, performs the specified operation. If the code is not authenticated, the operation is not performed. The code may be determined as a function of a one-time password generated by the authentication server. The function may also take as an input an identifier of the operation to be performed.